HsaINT0076353 @ hg19
Intron Retention
Gene
ENSG00000156515 | HK1
Description
hexokinase 1 [Source:HGNC Symbol;Acc:4922]
Coordinates
chr10:71148953-71152064:+
Coord C1 exon
chr10:71148953-71149052
Coord A exon
chr10:71149053-71151880
Coord C2 exon
chr10:71151881-71152064
Length
2828 bp
Sequences
Splice sites
5' ss Seq
TTGGTGAGT
5' ss Score
9.27
3' ss Seq
TGCCCCCTCGTGTGTTCCAGGGA
3' ss Score
10.98
Exon sequences
Seq C1 exon
GAATTTGACCTGGACGTGGTGGCTGTGGTCAACGACACAGTGGGCACCATGATGACCTGTGCTTATGAGGAGCCCACCTGTGAGGTTGGACTCATTGTTG
Seq A exon
GTGAGTGTCCTGGAAGGTCTCTTTCCCTGCAGAAGGGAAGGCTGGGGTTTCCCCGTTTTGTGGGGCCTTGGCCCAGCAGCTTGGTCCTCTGTATGGGGTAGTCTTATCTGTCAGTATCATTTCTTGACCAGCTCCAGAGTTCAGGGCTGGACGAAGGCAGCAGAGTCTCTGGCGGGGGGAGGTGGGGGGGCCTTTCTTAAGACACCCATAATGCTACACATTGCTTATGATCAGACTGTCAAGAACTGAACTCTTCAGGAATGAGGACCCAAAAGGCTCACTTGGCTTGAGTGGAGACAGGTACCTGGAGCGGGCCTGGCAAACATGGCAGCTCTATGGGCCTTGTATGGAGGGGCTCTGGTCAGGTATTGCAGGGGGATGGGGTGGGGAGGGAGTCTGCGGCTGGAAAGGAAGTAGAGAGCACCTCCCATGCTGACCACACTTAGAGCATGGAAAGGGGCAGGATGGTCTTGGGCACCATTTTGCCTTTAGCAGCCACTGTGTGCGCATGGTCCCAGCCACTGAAGGGGGTTGCAGAGGGGTTGTCTCTGCAGCTCGTTGCCTTGTAATCCAAAACACATTAGGGGTCTGGGCCTCGAGCACATAATTCCTGAAGCATATTGATTTGGGCTATGAGGAAACCATTTGTCCTGCTGGCCCTGCTCCTCGCGTCAGGGGATGCTGGGAAAGACCCCAGGGAGTTTCTTAGCCAACATCTGCGGACTCTGCCTGGTGAGTGAGCAGTGGCACCCCTGCTACTGGATCAGTTGCTGAGTGTCTAGAGCTTGGGAAGAGGCCCCAGCAGGCTGCCTTCCAGGTGCCAGGAAGAACTTTTCATTCATTGTTAAGCCACTTTTCGCTTCTGTTGAAATTTTAAAAAACCTAGGGAGCAGCTGCTGGTGAAAAGGTTGTTTGGGGCCTGGCTTTCTCCACCCAGCCCCTCCCTTTCTTTCCATGAATGGGCTTGGGTATGAAATGCAAAGCTAGAGTGACACAGCAGCTCTCCTCCTCCTGCAGGCCCCACCTTCCCTCCTGGGAGGTCAGGCCCGCCCGTTTCCTGGCACCAGGCTCCAGCTACATTTCATAGCTACTTCATAGCTACTTTTTCTTTCCTCCATCAATTGATCTCTTTGCTCAGGACTCCCATAGGCAAGATGTATGGTTTCCATGTTTTGGCTTTCTTTGCATCTCCCACTCCCATCATCTTCCGTTTCTGGAGCTCCTCTTCTCTCAGTTTTAACCTTGGGTGAAAAGGGGGCTGAGAAAACAAAGAACAAAAATCATCCAACTGTACAGTCTTTGAACTCTACTTAAGTTTCTTCAAAGGGGATGAAAACTACCAAAGCCCTTTTGGTCTGGCCAGGGGGTGTGTCTTGTGCCCTCCCGATGAAAGTTCACCTACATCCCACCCTGGATGGGTGGATGGTGCTCCTGGGCGCATCATTAGCATCATCCTGGGAGCTTGTTAGAGATGCAGGCTCTCAGGTCCTGGCCCTAGCCTCTTGAATCTGGATCTGCTTCTTAGGGTCCCCAGGTGATCCAGGTGCATATTAAAGTATGTGTGTGAAGCACTCTTCCTGGGTTAGTTGATTGGTTTTTAAATGTCCAGTCTATTCAGTGAGGCAAGTTCAGTGACCACAAGCTTGGATATCATGGCAATTAAAATTGCTGTGAAAGTTGCAGGATGCTTGCCTTCAGTTTCTTAGCTCCTCATGGGCTGGAACAGCAAACAGTCGGTGGTCCTTCTATTTTGAGTGACTCTGCTCTAGGGAGTTCAGGAATGGAAGTCAGAGATTCCTGAGCCCCTGGCAAGCATATGTCAGGTTGCATGTGTGCGGTGTGTGGGTCCACCCAGAGAAAGGTGCCTTTTTCACAGAAGAATCCTCTGATCTTCAAAGGTCTGATACAAAAATGATGAAAAACCATTGCTTTTGAAAGCCCCCCTTGAAATGCTGAAGACACTGTCCTGCCCTGAACTGTGGGCTTCATCCCAAGGTATGTAGGAAAGCTTATTGAGCAGGCATAGTCCACGACCAACCATCCTTGTCGAGAAAAGATAAGTGGGGCTGGGCGTGGTGCCCACGCCTGTAATCCCAGCACTTTGTGAGGCTGAGGCGAGAGGGTAGCTCGAGCCCAGGAATTTGAGATGAACCTAGGCAACATGGCAAAACCCTATCTCTACTAAAAATTTTAAAAAATTAGCCAGGCATGATGGTGGTGCCTGTAGTCCAGCCACTTGGAAGGCTGAGGTGGGAAAATCACTTGAGCCCTGGAGGCGGAGGTTGCAGTGAGCCAAGATTGCGCCGCTGCACTCCAGCCTGGGTGACAGAGCCAGACCCTGTCTTGAAGAAAAGAAAAAGAAAATAAGTGAATATCTATGGTATGATAGAAGATAATCCCCTAATATTTTATACACATATATATAGGCATGTATATATTGTATATTCATGTGTGCATGATGTTGTGTGTGTACGTATATATTTCTTCTTCTGGTCTGAATGTTGCCTAAACCTCTACCATTGATGCTCCATCTCTTTGCTATAAAGCCATCTTCTATTAAAATAAACATAACCCTGCCTGGACGGGTGAACACATTGGCTCTTGGTTGAAAGTCAGCTAAGCAGGTGCCCTCTGGGTGATGTGGCTCAGACTCTCCATTTACATTTCAAATTTTTCCATTTCAAAATTGGGAAAGAAAAACTATTACTTTGTTCATCACAAAAAACGTGCCCCCTGCCTGTGGAACCTCAGGCCCCAGACCCCAGGCCCAGTTGCAAGACCCCCAAATGCAAGGCCACCGCTCCTCATTGCCCCCTCGTGTGTTCCAG
Seq C2 exon
GGACCGGCAGCAATGCCTGCTACATGGAGGAGATGAAGAACGTGGAGATGGTGGAGGGGGACCAGGGGCAGATGTGCATCAACATGGAGTGGGGGGCCTTTGGGGACAACGGGTGTCTGGATGATATCAGGACACACTACGACAGACTGGTGGACGAATATTCCCTAAATGCTGGGAAACAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156515-HK1:NM_033496:14
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=PD(11.2=67.6),PF0372711=Hexokinase_2=PU(3.3=23.5)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(25.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)