HsaINT0076354 @ hg19
Intron Retention
Gene
ENSG00000156515 | HK1
Description
hexokinase 1 [Source:HGNC Symbol;Acc:4922]
Coordinates
chr10:71151881-71154861:+
Coord C1 exon
chr10:71151881-71152064
Coord A exon
chr10:71152065-71154705
Coord C2 exon
chr10:71154706-71154861
Length
2641 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACC
5' ss Score
9.24
3' ss Seq
GGCCCCTCCTCCTGTCTCAGGTA
3' ss Score
8.88
Exon sequences
Seq C1 exon
GGACCGGCAGCAATGCCTGCTACATGGAGGAGATGAAGAACGTGGAGATGGTGGAGGGGGACCAGGGGCAGATGTGCATCAACATGGAGTGGGGGGCCTTTGGGGACAACGGGTGTCTGGATGATATCAGGACACACTACGACAGACTGGTGGACGAATATTCCCTAAATGCTGGGAAACAAAG
Seq A exon
GTAACCCCGCCTGGTGGAGAGGACACTCACAGTCAGGGTGGGGGCAGCACTTGGCTGCATTCTGCCACTTGCAGTGGAAGAAGTTTCTAGGAGGAGAGGTCTGAACAGAGGTTTCAAGACTGGACCCCCTGGCTCACTCCTGACCTTTGTCTTTTGGACAGCAGAGAACCAGGGAGGACAGACCCCCAACATGGTACAAGATGGCCCAGGGTTGATGCCTGTCTAGGGGCTGCCTGTGACTGTTTTTTAGCCTGGAGGATTCTGGCCTTCCGGTCCCCTTGCTGTGTTCCTTTCCCATCAGAATAACAAGGGGGTGGGGTGAGGGTGGCTGGGCGGCAGGTTGGTGTGAAGCAGAGGCCCTGTCGCAATCGTCCTTTCCTCCGTGAGCCTCCTGCACCACCTAGTGGCCTTGTGGAGCTTTGCAGCTCAGGTCTCAGGTACCATGTCTGAAATGGCAGTGTCTGCCCTTTGTCTCAAGCCCCCAGGAATCAGGCCATCCTCTGCCACGGCCAGGATGAGTTGGTCCAAGTTGTCTCCCTAGGAGCAGAAAGAAGGGCTGGAGCAGCACCCAGCATGAGTCACTCCCTAGCCCCCTCAAGGTTTTTGCCTTTTCTAAATACCACCCATGCTGTTATTTACTTAGTGCTTTTCTTCGAATCAGCTTACAGTTTTTTGTTTTTCTTTTTGTTTGAGGTGGAGTTTTGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGTGATCTCGGCTCACCACAACCTCCACCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCCAGTAGCTGGGATTACAGGCATACACAACCATGCCCAGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTTGAACTCCCGACCTCAGGTGATCCGCCTGTCTAGGTCTCCTAAAGTGCTGGGATTACAGGTGTGAGCCACCGCAACCAGCCCTTATAGTCTTTTTCTTTTCTTTTCTTTTCTTTTTTTTTTGAGACAGAGTCTCACCCTGTTGTCCAGGCTAGAGTGCAGTGGTGCGAGCTCAGCTCACTGCCACCTCCTGGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCAGGTAGCTGGGATTACAGGTGCACGGCACCACGCCCAGCTAGTTTTTGTATTTTTGGTAGAGACCAGGTTTCACCATGTTGGTCAGACTGGTCTCGAACTCCTGACCTCAGGTGATTGGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTATAGGCGTGAGCCACCGTGCCCAGTGGCCTTTAAGGTCTTTACTGACATTTAATGAAGGAGGAAAAAGAGGAAGAACCAATAGTACCATAAAGAGATGGTAACTAAAAAATGAGTATAGTGAAGAACCGTGCTATTCAAGTCTAGCTGATGCTGTCGCCTACCAAATGACCTGAACTAAGACCCCCTTTGGGCTGAGTGCAGTCTATCATCAAAGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGAGGATTGCTTGAGCTCAGGAGGTTGAGACCACCCTGGGCAACATAGGGTTGAGACCCTGTCTCTACTAAAAATTAATAACAATAATAACAACAATAATAGTAAGACCCCCTTGGTTAAAAAGCGGGGGGATCAGCAAGTGTTGGAAGGGGTTAAGGACATGTCAGCACCAAACTGGGGTGGTCTTTGTGGTGGAATGAGAAGGACTGGGTGGGACTTCGTAGTGGTGGCCCACCCCTCTGTGATTCCATTCTGTTTCATGTTCTTCCATGGACCACATGAAATAGGAGGAATCCTGGAGTTCCAAATTCCAGGGGACTCTTCTCAGCTTTGGGACACTGGGCTTGGGCATGTGCCATGGAAATGAATCAATCCTTTGTTATTTCTTGAGATCCTTGAGCATGGAGAGGGCAGGAAATTTGAAGTCCCAAGAACAGGTTGACCTCCAGTGTGTTGTGGTCACTGAATTCTCCCTCCTGTGTGGCCTCATCACTCTGCTGTGGGCTTGACCAGTACTCTGGGTATTTGCAAAACCTTTAGAAAAATCTAGAAACTTTCCTTTTTTTTGTCTTCTTGTTCCTTTAAGACTTAGCCCAGTCATTTGCTTATTCTGCAGATAGTTTTTGGGCACTTTCCTGAGGGCCCAGTGCTATGCTATGCTGTGCTGTGCCCTGGGGACTCAGAGCTGAAAAAGACACACATGCCCTGTCCTCTTGGGGCTGTCACTACAGCAGTGGTGGTGGGAGGCAGTGAGCTCAGGTGTGTTGTGAAGGAGGAGAATGGTGAGGTGTGTGGGAACCTGAAACAGGCAGGTAGAACCCAGGATCAGGAGGAGGACAGGCTCTCGGGGAAGTGACCTTGGGGCTGAGAGCTATCAGGCAGCTGAGGAGGGAGACCAGTCTAGCAGGTAGACATGAATGCTGGTGGTTTTGTTTCTGATGTGAGAGAGTGGAGGACTCCCTGGTCCTTCCTGGTCCTCCCACTCTGCCTCTGCGGCAGAGCACAGGGCTGGGCACATGGCTGTTGATGATGCGCTTGAGGGGCAGTAGGAGACGCGGAGTGACCGTGAGACCGAGGGGTGACAGTTCTCCTGGCCACTTCCCATAGACACCCCAGGCCCCTCCTCCTGTCTCAG
Seq C2 exon
GTATGAGAAGATGATCAGTGGTATGTACCTGGGTGAAATCGTCCGCAACATCTTAATCGACTTCACCAAGAAGGGATTCCTCTTCCGAGGGCAGATCTCTGAGACGCTGAAGACCCGGGGCATCTTTGAGACCAAGTTTCTCTCTCAGATCGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156515-HK1:NM_033496:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)