HsaINT0076378 @ hg38
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:HGNC:4923]
Coordinates
chr2:74887903-74889478:+
Coord C1 exon
chr2:74887903-74888058
Coord A exon
chr2:74888059-74889244
Coord C2 exon
chr2:74889245-74889478
Length
1186 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
3' ss Seq
CTGTCTCCCTCCCACCCCAGTGA
3' ss Score
9.19
Exon sequences
Seq C1 exon
GTTCGAGAAAATGATCAGTGGAATGTACCTGGGTGAGATTGTCCGTAACATTCTCATCGATTTCACCAAGCGTGGACTACTCTTCCGAGGCCGCATCTCAGAGCGGCTCAAGACAAGGGGCATCTTTGAAACCAAGTTCTTGTCTCAGATTGAGAG
Seq A exon
GTGAGAGCTTAGGGCTCAGGGTAGCAGGGGGGCCATGTCCTTTTTTCTCACTGGCAGACAAACTGAAGGATTTCCATAACTCAGGGCATGACTCATACAAAAGTCAGTTTAGTGGCAAACACATTCATGTCTATAGTGTTTACTAAAAGCACATTATGGGCAGTTGTCATTTTAAGGGCAAACAGAGCATTCTCATGAAAGTTTGTGCTAAGCCTGGCCTGAGGTCATGCAAAGTGATATTGTTGGGTTTTAGACCATGTATCAAAGGTAGAAAGATACCTGCTCATAGCATGTAAATTGAAACGCACAGAGGAAGATAACCTATTAAAGCATCCACACTTGGCTTGAAAGCCCTTCCTAACTGCTGGCTGCAGTAATCAGGCAGCCAGGATTGAGTAAAGGTTGGAACGTCAGGCAATGCAGACACATGCCACACAGTGGCTCATTAGAGCAAAGCCTCCCTCCTACAGTCAAATGGTGGAAAATCTCCAAATTAGAACAGTGAATTTCAGAGCCCTTTAAAAATTAATGCTGTGCCATTACTCTCAGGGCAGAGAAGAACAGGAACTAGACAACTGATGTGAGTAGACCCCTCGGGCATCTGCACCAGTGAATAGAAAGATATATTCTAGCTTATAGGTCTGTTATGTTCAGCGAGGTGATTCCAGGCTTCTAAAATAGCTTTCTTTATATAGGAGGGTTTATTTTCTTTCTATAACTTTATTTACACTTCCTTCGTAAATAGCATATAAATACAGTTCAGACCACCCAGAGCAGCAGAGCAGAAATAAAGCACGAGTCTAATGCTGCTTGGTTAGTTCCTGCCCTGCAAACCCATGAACAGCAGCGAGAAAATGGACATGAAAGAGCTTTGTAACTGACCACTGTGATAAACAGTGAATTTGCTTTGTTTTGAGTATCTACTTTGTAGTAGTAATGGTCTATCTGGAGTAGGGAGAGTAGAATGAGGAGCTGTTTGTATTCCTGTCACCGTCAGGAAGAGTCAATGCAGTGCAGTAGGTTGAGCAGTGGTCTGAATTTAGGAATGGGAACCACCTCGAGGGGCCAGCTCCTGGAGAGCTAGACCCCCACAGAGCCTCCCCTGTAAGGACTCAGGCCCTGGTGTGGTAGGCTACCAGCCTTCTTGGTGCATGACTGAACACTTGCTGTCTCCCTCCCACCCCAG
Seq C2 exon
TGACTGCCTGGCCCTGCTGCAAGTCCGAGCCATCCTGCAACACTTAGGGCTTGAGAGCACCTGTGACGACAGCATCATTGTTAAGGAGGTGTGCACTGTGGTGGCCCGGCGGGCAGCCCAGCTCTGTGGCGCAGGCATGGCCGCTGTGGTGGACAGGATACGAGAAAACCGTGGGCTGGACGCTCTCAAAGTGACAGTGGGTGTGGATGGGACCCTCTACAAGCTACATCCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399:ENST00000290573:16
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(21.7=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(32.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTGGGTGAGATTGTCCGTA
R:
AGCTTGTAGAGGGTCCCATCC
Band lengths:
355-1541
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development