HsaINT0076384 @ hg19
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:4923]
Coordinates
chr2:75100971-75101576:+
Coord C1 exon
chr2:75100971-75101070
Coord A exon
chr2:75101071-75101392
Coord C2 exon
chr2:75101393-75101576
Length
322 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
3' ss Seq
GCCGTCCCTTGTTTTGGCAGGCA
3' ss Score
8.69
Exon sequences
Seq C1 exon
GACTTTGATATCGACATTGTGGCTGTGGTGAATGACACAGTTGGGACCATGATGACCTGTGGTTATGATGACCACAACTGTGAGATTGGTCTCATTGTGG
Seq A exon
GTGAGTGAACACCGTGCATGAAGGGCCCGTGCTGGCCAAGGGATGGGGGTGTGGGCTGGAAAGGGAGAAGGGGCCCATGGGCTGGGTGTTCCTTTGTAGTTCATATTAGAAGATAATGGTCCAGTCACTTTGGAGAGCCGAGCAGGGACTCATGGAGTTGGGGGTGGCAGAAGATTAGACCATGTATTGTGATGCCCCCAGAGTCTGCAGTGAGAAATCCCAGCCATCCTGGCCGGGCAGTCTCGGGACAGTAGTATAAGAGGGAAGAGGGGTGGGAAGGGGCCGGAGCAGGCGTGTGCATAGCCGTCCCTTGTTTTGGCAG
Seq C2 exon
GCACGGGCAGCAACGCCTGCTACATGGAAGAGATGCGCCACATCGACATGGTGGAAGGCGATGAGGGGCGGATGTGTATCAATATGGAGTGGGGGGCCTTCGGGGACGATGGCTCGCTCAACGACATTCGCACTGAGTTTGACCAGGAGATTGACATGGGCTCACTGAACCCGGGAAAGCAACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399-HK2:NM_000189:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0034916=Hexokinase_1=PD(11.2=67.6),PF0372711=Hexokinase_2=PU(3.3=23.5)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(25.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATATCGACATTGTGGCTGTGG
R:
GTTGCTTTCCCGGGTTCAGTG
Band lengths:
278-600
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)