HsaINT0076385 @ hg19
Intron Retention
Gene
ENSG00000159399 | HK2
Description
hexokinase 2 [Source:HGNC Symbol;Acc:4923]
Coordinates
chr2:75101393-75104448:+
Coord C1 exon
chr2:75101393-75101576
Coord A exon
chr2:75101577-75104292
Coord C2 exon
chr2:75104293-75104448
Length
2716 bp
Sequences
Splice sites
5' ss Seq
ACTGTGAGT
5' ss Score
7.94
3' ss Seq
TGGTTTGTGTCTTCCGGCAGGTT
3' ss Score
10.7
Exon sequences
Seq C1 exon
GCACGGGCAGCAACGCCTGCTACATGGAAGAGATGCGCCACATCGACATGGTGGAAGGCGATGAGGGGCGGATGTGTATCAATATGGAGTGGGGGGCCTTCGGGGACGATGGCTCGCTCAACGACATTCGCACTGAGTTTGACCAGGAGATTGACATGGGCTCACTGAACCCGGGAAAGCAACT
Seq A exon
GTGAGTAGGCCCTTCCTGTGCGAGTGGGCTTGGCGGGGGCCTGGAGCTGAGTCTGGGGCTGGTCGGGGCCAGGGGGTTGTTTCTTTACAGTCTTACATCCCCAAAGCTTGCCAAGGTGGCCACTGGTCATAGGAATGTCTGTGACTATAAATTGCTGAGAGGATCTAAAACAGAGAGCAAGCGGATATACCAGATTATAGCTAATAATGTGTTTCCTTCACAGGAGTCATTTTGGAAGGTTCTATTCTGAGTGTAAGTGGGTGGCCCTGCTCTTTCTTTCCACCTTCTATTTGTAAATTGTCCATGGGAACTGTGAGCCACCTAAGGAAAGTTGTGTTGAGGTGGCCAAGATTGGGGTCTCTGAAAGCTCCTTTCATAGCTCCAACTCCATCACCACCCAGAGGACAGGCTGACAGCTGGCTGCTCATTGCTGCTCCCTGGGGTCCCAGGGCCTCCTGCTGCAGCTGCAGGCAGACCCATGGCCCCTGGAGACATTGGCTGAGGAGCTTCCTTGGCCTCCTTCACTTGGACCTTGGCCCAACTATGTCCTGGGATGGATTGGAGGAGGGGCGTCTAGCATTTTGGATCCTGAATATTGTATTCTCCAGCCTGGCCTGCCTTTGTTTTTAGTTGCTTTTATCTCTTACAAAACCTTATTTCACCCTCACAAACATTTGCCAAATGTGCGTGTGAAAGATCTTGAAACAGGGATTGCTTCAAGGTCTGAAGCAGTTGCAAAATATTTTGAGCAATACAGATCATCTCTGGTCTTGTGACTGTTGTAGAAAAGCTTTTCGTGCAGATCTCTACTTGGACAGGAAAATTGAACCCTATAAATCAAGTCAGTGGTGGGTAACCCAGGAGAGTCCTTGCTTTCGTTTTTTTTTTTTTTTTTTTGAGACAGAGTCTCTCTCTGTTGCCCAGGCTGGTGTGCAATGGCGCAATCTTGGCTCACCGCAATCTCTGCCTCCCGGGTTCAAGCGATTCTCCTACCTCAGCTTCCTGAGTAGCTGGGATTACAGGCGCCTGCCACCACGCCCAGCTAATTTTTGTATTTTTATTAGAGACAGGGTTTCACCATGCTGGCCAGACTGGTCTCGAACTCCCGACCTCAGGCGGTCCGCCCTCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCTGAGAGTCCTTGCTTTGTCAAAGCATGGTTTATTTATCTAAGTCACAAGCTTGTTTCACATGTTGAAATGAGTCCTTTACTTGAAATTTCTGAGGATCATACTGGTTGTGTCTGCCATGGCTGATGAGAGGTTTATGAGCTGAAAAGTCACTCAGTGCCTGCCTCCATGAATGAGGCACACCCAAGTCATTCCGAGGAACTAAAGGCCCTTTCAAATGTCAAAAGACAAATTTGCCAGCCAGACCATGACAGCACACCCCCGGCTTATCCTTTGACACCCACCAAATTGTCATCCATGGTAGCCCTGAAGTCACTACAGACAATTTTTGTCCCCTCTAATATATTTCCAAGTAAGTATCTTCCAAATGTTGACTGGAACAAAGTGTTTTTAAAAACTAGAATAAAAACTTAGCAACACGGAGTTCCTTACTGTTGAAGCCAGGCTCCCATCCACGCTGGTTTCCTTCTCCTGAAGCTCTGCCTGTGTGGGTGCACTAACATTTAAAATGCGCGCTGTCATCTTCACAATTTTGCCAGCTCTCAGTTAGCCCTGATGCTGCTGTACTCGGCCTTGGGTCTTGAGCAGGCTGCTTCCTGGAGGCCTGGGTTTCCTCTCGGAAAGGTAACCTTGGAATCCCTTCCACATCTCAGTCCTGGGCCTCCTCCTCGCTGGGGCTCATCCTAGTTAGTGGCAGCAGGCCCATGTGCCTCCTCTAAGACACAGGTTCTTTCTCAAACACCCAGAAATGGGCCTTTTGTCAAAAAGAATTATCACCAGGGCTTGGTTTCCTCTCAGTTCTAGTCAGAAAGACCAATTATGAAAGAAAACAGTGCCACCTAGTGTTAAAATTAAATCACCGGACCGCACTGCTGGTTTGGGGGCCGTCCCCTGCCTTTCTAAAACATCTTGTCACCTGCCTGCTTAGAAGCCTGTTTCACTCCCAGACCCCTGAGACCTGTCATTTAGAGCTCGGAGCCCAGTGCAGATTCCTCTATCCCAACCTGCCTTTATAATGTTGCCCCATCATCCCCTGCCCCAGGTGGTTTTCACACCATTTTCTCTGGAGCCCATGAACGGCTTGCAGGGGTGGACAGTATGAGCTGATGAGTTTCTAGGCCTGTGCTACATATCTAATCAGATCGCCTTTTTTCTCTTGTAAATAAATATTGGGCTATGTAAGATATTAATTTTAAAAATGATTTCCTGGCTAGAGAAGAATTTTAAAGATTACCACCCTACGCATAACTTTACCTAAAATACAGGCTGTTCCAGAATGTTCCATACTCCCTGTGTGTTTCATTTGGCTGCTTAAGTTTCATTTATTCTTCTCCATAGGTCAAGGCCCATCAGCCTGCAGGGACAACCCAAGCCAGCCCCTCTGAGCCGTCACCTCTCCACGTATCTTACTCCTGGGCCGTGCTGCACACATTAACCCTTAGTTGTGAAGTTGCACGTGTGCGCATCTTGCTTCAACAGGGAAGCTATGAGTACATGGGCAGTGGGGACTTTATGTTTTTGGTTTGTGTCTTCCGGCAG
Seq C2 exon
GTTTGAGAAGATGATCAGTGGGATGTACATGGGGGAGCTGGTGAGGCTTATCCTGGTGAAGATGGCCAAGGAGGAGCTGCTCTTTGGGGGGAAGCTCAGCCCAGAGCTTCTCAACACCGGTCGCTTTGAGACCAAAGACATCTCAGACATTGAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159399-HK2:NM_000189:7
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)