HsaINT0076412 @ hg19
Intron Retention
Gene
ENSG00000156510 | HKDC1
Description
hexokinase domain containing 1 [Source:HGNC Symbol;Acc:23302]
Coordinates
chr10:71018532-71021050:+
Coord C1 exon
chr10:71018532-71018715
Coord A exon
chr10:71018716-71020894
Coord C2 exon
chr10:71020895-71021050
Length
2179 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAAG
5' ss Score
4.41
3' ss Seq
TATCCTTCTTCTCCAAACAGATA
3' ss Score
11.3
Exon sequences
Seq C1 exon
GAACAGGCAGCAACATGTGCTACATGGAGGACATGAGGAACATCGAGATGGTGGAGGGGGGTGAAGGGAAGATGTGCATCAATACAGAGTGGGGAGGATTTGGAGACAATGGCTGCATAGATGACATCTGGACCCGATACGACACGGAGGTGGATGAGGGGTCCTTGAATCCTGGCAAGCAGAG
Seq A exon
GTGAAGAGGGTGGATGTGTGCATTTATGTGGGTTGTGTAGTGAACAACACTACCAGACCTAAGGGGGTACCATAGACAGCATAGCTTTGTGTGCTTATTACAGCTGTCGAATGTCAGTGAAATATCCTATTGGAACAAAAGAAAAATATGATGACAAGTTTGCAACAGGTAAAGGGGAAAAGTCCCTTTTTCTAATTACCATAAGGCCCCATAAGGTCTAGTGGTGGTTCTGGAAGTGAGGCAGAGGCTGCCAGCATGTTCATTCACCAAGGGCATGGTAACTCAGTGAGCCTTCTTGAGATGGGCTTTTAATAAGTCTCTTTCAGAGGCCAACATCCTCAGGCCTTCAAGAGCTGGCTACCAGGTTGGTGACCTTTTCTGGGAGTGGGGAAGTGGCCACCTGTGATGGATGAGAGTGCTGGTTCTCGACCATGATGTCATGTCCCACCACGGGTCACAATCACTTGTGAGGTGTATTCCAATGACTAACCACATGAAAAATACTGAAAATAATGAATGGCCTAAAAAATAAATTAGAGTAGATTTCACTTGCATTATGATATTATGAGAGAAAGGGGTAGCAGAGCTAGAGCTGGCATGTGATATTAGTCCATTCTCCCGTTGCTGTAAAGAACTACCTGAGACTGGGTAATTTATGAAGAAAAGAGGTTTAATTGGCTCACAGTTCCACAGGCTGTGCAGGAAGCATGGCTGGGAGGCCTCAGGAAACTTACCATAATGGCAGAAGGTGAAGGGGAAGCAGGCACGTCTTACATGGCTGGAGAAGGAGGAAGAAAGAGTGAAGGGGGAGGCGTTACACACTATTAAAATAACCAGATCTTGTGAGAACCCACTCACTATCACCAGAACAACAGGGGGGAAATCCACCCCCATGATCCAGTCACCTCCCAGCAGGCCCCTCCTCCAATACTGGGGATTGTAATTCAACATGAGATTTTGGTGGGGACATAAATCCAAATCATATCACATGCTAAAATTTGATTATTAACCCAGGCCCATCCACTAGAAGAGGAGTTGGCACACTTATTCTGTAAAAGAACAGATAGTAAATGTTTTAGGTTTTGCAGGCCATATGGTCTTTATCAAAACTAAGCTCAGTGTCTTAATATAGAAAATAATGGGAAACATAGATTTATTGTTATGGGTGCTATCCAAGTTGAGAGCTTGAGCAGATGGGAAATGTGAGGGGATGCTTAGGCCATGGACACCTTGGGAGCTGTTGAACTGAGAATGTTGTCTAGGAAGAGGCTCAGACAAGACCAAGACTGGCCCTGGTGGTTTCTTTCCTCTTTGGCACCAATCTTGTAACTGGAAGGCAGGTGAGTTGTGGTAAGCCCAGCTGAAGCAAGGATTGCTCCAAAAAGAAGGGACCTTCCCTTTGAATCCCAAGTTGGGGCACCTGAGTGTCATGGCTCTTCCCAAGGGGCAGTTCATTCTAGTTAGCTTTGTGTCTGTAGCCACTGAAGGCTCACATTTTTGGATTGAGGTTTTAAGGGGGCAGCACCTTTGAACTTGCCTTGAAATCACCATTTTTTGTTCTGGTGTTAATTCCCTTAGGCTGATGAGGTCTTGAGCAGTTAAGAGAACCCAAGCCCAGCACATAAATGCTTCCCATTTGACTCTGCAAGCAGTGGCAGTCTGGCTCTGTGTCACTGTTGTTAATGATGATGTGTGTCACCATCACACACCCTGTGCAGAGTGCCTGGTCAGTACAAGGCCCCTTTTCTCTCTTGCTCTCTTGACCCTCATGGAGCTCACGGTCTGGTAGAAAGGAGGAAGGGAATTAATGCTTTTGAGCACCCCTGGTGCATGCAGACAGTTTCAATGTGTTAACTCACAGAGTAGAATTTGCAGAGTGGAACAGATTTGTAGCACAAAGCCAAGGAGAATTGGCTTTGGGGCCAAGACCAGGGACTAAATTTTGCTTAGTGCCCACTGTACCCAGATGCTTGCCTCCTAACAGTCTTGTAGGGGCGCTACTCTTCTCCCTGTTTTGTAGATGATAGCTTGCAGTGCTTGCTCACATCAAGCAGCTAGTATGTGGCAGAGCTAGGATCTGGATCTTGCTCCATGCGTAGCTCCAAAGCCTGGCCTTCTCACATCATGTGGTCTTCTGCATTGCAGGTCTGCCCCAACCTTATCCTTCTTCTCCAAACAG
Seq C2 exon
ATACGAGAAAATGACCAGTGGGATGTACTTGGGGGAGATTGTGCGGCAGATCCTGATCGACCTGACCAAGCAGGGTCTCCTCTTCCGAGGGCAGATTTCAGAGCGTCTCCGGACCAGGGGCATCTTCGAAACCAAGTTCCTGTCCCAGATCGAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156510-HKDC1:NM_025130:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.062 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)