HsaINT0078779 @ hg38
Intron Retention
Gene
ENSG00000182054 | IDH2
Description
isocitrate dehydrogenase (NADP(+)) 2, mitochondrial [Source:HGNC Symbol;Acc:HGNC:5383]
Coordinates
chr15:90087439-90088502:-
Coord C1 exon
chr15:90088359-90088502
Coord A exon
chr15:90087576-90088358
Coord C2 exon
chr15:90087439-90087575
Length
783 bp
Sequences
Splice sites
5' ss Seq
GAGGTGAGG
5' ss Score
8.41
3' ss Seq
CCCTGTCTCTCCCCCTGCAGTCC
3' ss Score
11.74
Exon sequences
Seq C1 exon
TACAAGGCCACAGACTTTGTGGCAGACCGGGCCGGCACTTTCAAAATGGTCTTCACCCCAAAAGATGGCAGTGGTGTCAAGGAGTGGGAAGTGTACAACTTCCCCGCAGGCGGCGTGGGCATGGGCATGTACAACACCGACGAG
Seq A exon
GTGAGGCTGGCTTGGGCATCCTGGGCCCCTCCTCTCCCAGCTTGTCTCTTCATCTCTGTCTCGTGGCTTTCCTTTCTTCTGTAATGGCCTCATTCTTAGGCCACAAAGAGGCAGAAATGGCCACCAGGGCTGGGCATGGTGGCTGACACTTGTAATCCCGGCATTTTGGGAGGCCAAGGCAGGATTGCTTGAGACCAGAAGTTTGAGACCAGCCTGGGCAACAGTGAGACCCCATCTCTTGAAACAAAAAGAAAAGAAAAGAAAAGAAAAGAAATGGCCACGAGCAGCTCCAGGCGTACTCCTGCCTGCTTGGCTACCCTATCAGAAGAGAATGCCTCTTTATCCCCAGTTCCAGCTCCAATGCCAGGCTGAGTCACATGACCACCTCTGAGCCAATCACAGAGGCCCTGGGGAGAAAGGCTTCTGATTGGATAAGCCAGGGACACACTGTCAACCCCAGCGCTAGGCCTGGGAATTAGCCCTGCCCCAGCCACATGTAGTCTAAGGCGGTGCTTTCCAAAAAAAAGTTGTTTCCAAAAAAAAAAAAAAAAAGGCGGTGTTTTCCAAAAAAAAAAAAAAGGCGGTGTTTTACAAAGCAAAGTTGAGAGGGAGAGGCTGGGCCAGCAGAAACATCGTGTGCACTGCACGGAGGCTGGTGTTAAACAGTCGCGTGGGCGGCGGGGTACCGTTCCTGGAGAGCTGGGCCTTGCCCTGGGAGGTGGGAGGTTGCCGGCAATCGCCAGGCTAGGGCACCACGCCAGGGCCCTGTCTCTCCCCCTGCAG
Seq C2 exon
TCCATCTCAGGTTTTGCGCACAGCTGCTTCCAGTATGCCATCCAGAAGAAATGGCCGCTGTACATGAGCACCAAGAACACCATACTGAAAGCCTACGATGGGCGTTTCAAGGACATCTTCCAGGAGATCTTTGACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182054:ENST00000330062:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0018015=Iso_dh=PU(11.5=50.0)
A:
NA
C2:
PF0018015=Iso_dh=FE(11.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACAAGGCCACAGACTTTGT
R:
TGTCAAAGATCTCCTGGAAGATGT
Band lengths:
279-1062
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development