HsaINT0082964 @ hg38
Intron Retention
Gene
ENSG00000105855 | ITGB8
Description
integrin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:6163]
Coordinates
chr7:20398860-20402126:+
Coord C1 exon
chr7:20398860-20398994
Coord A exon
chr7:20398995-20401720
Coord C2 exon
chr7:20401721-20402126
Length
2726 bp
Sequences
Splice sites
5' ss Seq
GAAGTATGT
5' ss Score
6.97
3' ss Seq
CTTTTTCCTCCTAAATTTAGGTT
3' ss Score
10.71
Exon sequences
Seq C1 exon
AAGCTCATTTCAGAAGTGAAAGTTCAGGTGGAAAACCAGGTACAAGGCATCTATTTTAACATTACCGCCATCTGTCCAGATGGGTCCAGAAAGCCAGGCATGGAAGGATGCAGAAACGTGACGAGCAATGATGAA
Seq A exon
GTATGTGGGTGTGCATTTTTCCCTTTTAAAATAAACTAAGTTGTTTGGCGTACTTTCTTACAGAAAAAGCAAACCATTCTGAAAAATTTTACTTACTACTGACTCTAAGAATCTTATTTATACTTCAAGGAAACTTTCATTGTCTCTCCTCAAAGTTCCTACTTGTTTTAGCTCAGCTGATTGTTCTCTCCAACTCTCAGGTTTTAATATGTATATGTGTGTGCGTGTGTGTGTAATATGAAACAATCATGTATCAATAGTAACTTTAAACTTAGGCGTCATGACCGGTATAAATTAGGAAATCACATATTCTCAAATAAGTAGTGTCTGTACTTATAATAATGATAATGCCTTTTTGATTTCATATTCACAAACTCTCAAAGTAAATGTAAAATTGAAAGTCACATATCACAGAAAAGAATGGGAATGATAGAACAGTTGATAAAGGCTAAGAATTTCAAAATCTTTCACTTTGTGATTGCCCCAGTACACTCATAATTATCTAAATTATCTAGAAGGAGGTAGGGAAATTTATTAAGAACAATACAAAATGGGAAGAGTCATCATTTACCAAAAAAAAAAAAATGGGATGTAAAGGAGAGAGATCCAGATTGTAACAGTATCAGGAAACAGCACCAGAGGAGATAGAGATTCTCCAAGGATTGGCACAACGGAGAGAGTAACACAAAGAAACATACTCTTTAAGGGAGTCTTTGCTGGGTGAAGTGATTTTGATTGAGTCATTTACGTCATGAGGCATTGTCTCATGTTTAAATGAATGACTTGGACTAGTAGATTTCCAACCCCTTTTAATCTAAAGTGCAATGATGATTAATTATGTAATGTCATGCTATAGAAAAAAAGAAAAAGTTATTGAAAGTGATAGAAGATTCTAAAAATGAATAAAAGAGACTCTTCTCTTTAGTTAGAATATGTTTTTCTATCTTAGGAATTTTAGAGCTGTGTATTTTAAATTAATTATTGCAAGTTTCTAATTCTGTGGTTTCTTCTATGATCACTCCGTGGATTTTGTTCAAAGGACATCATATACCAGTTTGCAAAATGCACTTTGGCTTTTCATTAAAACTACAGAGAAAACTTTTTACTAGCAAATATAGCACTAAGTTACTTTATGAAAAAACGCTTACTGTCTTAGAAATAGTTATTTCCTTCAAAATGTCATTTTGGAAGAATGGTTTTTCTTAGCTTTTACATTGTTTTTTTTCTTTTCATTTGCTTACATGCCATCTTTCCTTCATTTTCAATTGAGTAGTATAAATAGTTTAACTCTCAGGAATAGTCATATGACCTCTTAATTATAGAAACCCCAGAGTATGATCTACTGTTAGAGATGGCAGTGGCCACATTAACTTATGTATCTGTTAAGCTTCAGCATTCTCAAAGACAAAAGCATTTTAAGCATAACACCAACTGTATTGATTTTAATATTATGGAACAAATTCTAATGTTTCATGTATATATAAGCCAAATTTAGATACTTTATATTATTATATCGTAGATATATATTCCAACCAAAAAGCTCAGCGCAAATTAATTTTAAATTGTAATGGATCTCAATCCAACGTGAAAGAAATATACCTTCTTATTTACCAAAGTACCTAAAGATGGTAAGGTGAGCCAACAAATATAAATAGACATATTAAATCAATTGTGTTGTGCAAAAAGAAGAAATAGAGAAAAAGAAAACATTTGACCAATTCCTGCCAGCACAGCTCCTTAGTTCTGGGCTATCTTCTTCCATGGAGACAAATAGATAACCTGTGTTGAGGTCTTAAGATTTGCAAATGAGAGTCCTAAACATTTTTCTTTCGAGTAACATCAGAGAAGGCCACAGGTTTTCCTCCACTGAAACCCTGTATAAACTAAAATTTAACTCCGAAACTTTACTTGGGCTCCTAGAAAATAGGAACAAAATTAAAACTGTTCATTTGAACATCTTATCTCAGGGTTTTGATTTTTATTTATTTATTTATTTTTGAGATAGAGTCTCGCTGTGTCACTCAAGCTGTAGTGCAGTGGTGCAATCTCGGCTCACTGCAACCTCTGTCTTCCGGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCTCCCAAGTAGCTGAGACTACAGGTGCGCGCCACCATGCTCAGCTAATTTTTGAATTTTTAGTAGAGATAGGGTTTCACCATGTTGGCTAGGCTGATCTCGAACTCCTGACCTCAAGTGATCCAACCGCCTAAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCCAGGCCTCATCTCAGGGTTTTAAACCAGTAGAGCAGAAGCCCTTTACTTTGGTTTATGTGATCTATCTCTAGTGTCAAATATTCAATACCCCACATTTTAATGGCTGAGTTTAGAAAATGGCCTATTCTTTCTCATGTTTGCTAAGAAATTAATCATCAGTGATGGGGTAGATGCTTCAGATAGGCTTGCACTCAAGTCTATTTAATGGTGCAATATAGGGATTAGTAGTTATTATATTCTTTAACCCTCAAGTTCATTCATTGGAAAATAAATGACTTTAAAAAGAGATGTTGCATATATATGAAAGAGATTACATGTGTTTCTTTTACAAATATCGTTAATTTCTCTAAGATGGTTTCTTATCAATTCAGTTATTAACAGATATAATATTGGTAATAAAAATAATTAAGGTATATAAATATATTTCCTTTTTCCTCCTAAATTTAG
Seq C2 exon
GTTCTTTTCAATGTAACAGTTACAATGAAAAAATGTGATGTCACAGGAGGAAAAAACTATGCAATAATCAAACCTATTGGTTTTAATGAAACCGCTAAAATTCATATACACAGAAACTGCAGCTGTCAGTGTGAGGACAACAGAGGACCTAAAGGAAAGTGTGTAGATGAAACTTTTCTAGATTCCAAGTGTTTCCAGTGTGATGAGAATAAATGTCATTTTGATGAAGATCAGTTTTCTTCTGAGAGTTGCAAGTCACACAAGGATCAGCCTGTTTGCAGTGGTCGAGGAGTTTGTGTTTGTGGGAAATGTTCATGTCACAAAATTAAGCTTGGAAAAGTGTATGGAAAATACTGTGAAAAGGATGACTTTTCTTGTCCATATCACCATGGAAATCTGTGTGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105855:ENST00000222573:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.022 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0036213=Integrin_beta=FE(10.6=100)
A:
NA
C2:
PF0036213=Integrin_beta=PD(12.3=30.1),PF079748=EGF_2=WD(100=26.5),PF079748=EGF_2=PU(28.6=7.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development