HsaINT0090385 @ hg38
Intron Retention
Gene
ENSG00000091136 | LAMB1
Description
laminin subunit beta 1 [Source:HGNC Symbol;Acc:HGNC:6486]
Coordinates
chr7:107932174-107935656:-
Coord C1 exon
chr7:107935415-107935656
Coord A exon
chr7:107932378-107935414
Coord C2 exon
chr7:107932174-107932377
Length
3037 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGG
5' ss Score
9.33
3' ss Seq
TGATCCTTGGCTTGTTGCAGACC
3' ss Score
7.26
Exon sequences
Seq C1 exon
GTGCCTTGGATAGCATTACCAAGTATTTCCAGATGTCTCTTGAGGCAGAGGAGAGGGTGAATGCCTCCACCACAGAACCCAACAGCACTGTGGAGCAGTCAGCCCTCATGAGAGACAGAGTAGAAGACGTGATGATGGAGCGAGAATCCCAGTTCAAGGAAAAACAAGAGGAGCAGGCTCGCCTCCTTGATGAACTGGCAGGCAAGCTACAAAGCCTAGACCTTTCAGCCGCTGCCGAAATG
Seq A exon
GTAAGGTTTGGGGATGTGGCCTTACTGCTATGGTGCCAAGCAAAAAAAAAAAAAAAAAAAAAAAAAACAAAGAAAAACAAACCATCTTTTGTCATTATTACAATAATTTGCAAATGAATCAGCAGGACTGAAACTCCTAGGCTGAGGTCTCTGGATCCTGGAATGGGGTATCTGTAACCAAGACAGATTAAAAGCAGCAGCATATGGGTTTCCAGCCTTCCCCTCTTCTGTTTCTCTGTGGTCCTCAACTAAAGAATGAATCATGACTATTCTCCCATACTGTTTTAGCTACTCAGTGACACCGCACTGAAACTTGATCCTTTTTACACTGTGGACATTTCTTTAATATTTTTTTTCCTAAGTAGAGACAGGGTCTCACTACATTGCTCAGGCTAGTCTTGAACTCCGGGTCTCCAGCAATCCTCCTCTCACCTCAGCCTCCTCCCAAAGTGCTGGGATTACAGGCTAACACCCCAGCCCACCCCCACCCCCGCTTTTTTTTTTTTTTTTTTAAAGAGATGGAGTCTCACTACGTTGCCCAGGCTGACCTCAAACTCCTAGGCTGAAGCGATCTTCCCACCTCACCCTCCTGAGTAGCTGAGATGACAGGCATGTGCCACCACACCCAGCTTGGACATTCCTTTTTTAGTTTGTTCTGATTTGAATTATAAAACCCATCTCAGTGTAGGAATTCAGAGTCATTCTAGAAGGGGCTTCCATTAAAAATTAAAGGGAGCAAAAGAATTTTTTCACGGGTATTAGCTATTATGTTCCTTTGTTCCAGTAACTTTACCTGGTGAAGATTAACCCTGAAACCAGCCTAGAAAGTAGATTCATTTCCCAGAAGCTTTTAAAAAGGAACTCTGGAGCCAAATGAAATTGGGTTGTGAGTTTAATGAAAATCAGGCAGAAGGCCCCAAAAAAGCCTAACTGAGCCTGTTTCTTCCTCTTCCTTCCTGTGTTTTCAAGGAAGGATACCTATGTGAAATAATTTGGAGGGTATTTTTTATAGACTAAGGTTTGTGTTCTCTTAGCCCAGAGACACAGAGAAAGTTAAAGATGGAAGGTACATAGGCGCAGAAGAGTTCAAACTTCATTACAGCTTTGTCTTAGTGATGCTTCCTCCCTCCTCTCATCACTTTCTCTGAAATAGACAAAATTGGTCACAATATAAGACAGTGTTTATTGATGCCTGCTAGGTTTCATACTCATTATCTTCTGAAACTTTATAGCAAATAGGGAGCAAATAATCTGTCATTTATTAAATGGAAAAATAAAAGATGAAGAAAAAAGAAAAATGAAGGCTTAGAGCAATGTGTAAATTGCAGCTAACAGGAGACAAAGTTATGAAGCATGAAATGCCAATTCTCTCCATCTTTCCCTTCAGCATTGATTCCTTCCTTACATATTGTAGTTAAAAAAAAAAAATCAGTTATCACAAACAAGTTCTGTGTGACCTACAAGAAACAGCTAAGCATGCTAAAGGATTTTTGTCTTGAACCGGAGGCATCTCCGTGGGCGGCAGGGAGATGCATGGGCGGTGGGTGGGGTTCGGGGTTCCTCTGGCCTTTCAAATGTGTGCCCTTCCCTGTGCTTGCTTTTCCACCTGGTAAACTACCTAGGGATTAGCAGCTGCTTCAGTTCTCTTACTGTGTTTTTGTCTTTGTTAATGATCCTGTGAGAATTCTTTCTGTAAGTTCTTTACTGCCATTTCCTTGTGTAGAGAGAGTTTTGTCCTTTTGTTTTTCAGGTACTTCTAGTTCTGTATCTTTGTGGATGTTTAGCTAGAGCCATACTGTGTTTTTTTTTTTCCATGTCTGCCCCATCTGTTGAAACAAAACAGATCTTCTATGTGTGCTGTCAGATTGTTTTTAGAAAGCAACCGAGGTTTTACACTTATGTTCTTAAGACTCATGTTTTACAGCATGCAGAATACACTTTATTTTCTGAAGCTTTTTGTTTTTGTAAGCCAGATAAATGACTTATTTAGTTGTAATTTGAGATATAATGGAATTATAATTATCTTAAAATTATTAGGCTAAATAGTTGATTGTATTTATTTAAAAACTACTTTTTTGTACTTTTTAATAACAATACTTGTTTGGGAATATTCTGTTAACTCCTTTTCACTGCAGTAAATCTTTGTCTTCTTTTCAGTATGAGAATTTCCACAAACAGCTCTAAATGCAATTTTCTCCCTGCTCAGCCTTTTCTATCATATAGCACACTTGTATTATAATTTATCAATTTGCATTTGTATGCCATGACCAAGTGGTGATCTTTGAGAGGTTTTGGTAGGTAAGAAAGGAGGACTCTATGCATGTGTGATGGCAGTCGGGGGTGGTAATTTGGGAACACTTCATCTACCTTTGTTCCTTTGTTTGTACTGTTTTCTTTAACCTGTGGAATGTTTTCCCACTTCCCCTGCTCAAATCCCACCAGCCAACAGCTTCTTCAGCTACAACTGTAGCATTCCTCTGCAGTCTCTCCTTTGTCTACTTTCTTTCATAGTGACTGCATCTGACCTATTCTTGGCTATTTTATGTGGAATGATCCAGTCCTAACTAGATGGGAAGTTACTAAAACGCTAGGTAATAGATCTTTTATGTCACCATATTTACTGGAGGAGTTAACATGGTGCTGGTGCTGGTCCCAAAGATGGTTCACAATAGGTTTTTTTTTTAAACTCTAACTGGTTAGAAAAAAAGGAAGGCATTCCTTGGCCCTTGCACTGGCAGAATTCAACTTGATATAGCAGATGTTTGCATCCTGGGCAGAGCTCATATAGTATTTTAACTCATTTGGGCAGAAGATATTGATGAGTTGTAAACTTCCATTGTTTCCTTGGAAATAAGCAGGTTAGTTTACTCCTAAACTCTCTGCTCCTCTCTCCATTCTGTCTCCCAAACACTGTTTTCAAGCACCCTTGCTGAGGACCACCTACACATTCTCTGGGGCCACCCAGGCCCTGCACAGCTGTTTTGCTGCAGCAGATTCACTATCCGAAGTATTGTGCCTGATCCTTGGCTTGTTGCAG
Seq C2 exon
ACCTGTGGAACACCCCCAGGGGCCTCCTGTTCCGAGACTGAATGTGGCGGGCCAAACTGCAGAACTGACGAAGGAGAGAGGAAGTGTGGGGGGCCTGGCTGTGGTGGTCTGGTTACTGTTGCACACAACGCCTGGCAGAAAGCCATGGACTTGGACCAAGATGTCCTGAGTGCCCTGGCTGAAGTGGAACAGCTCTCCAAGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091136:ENST00000222399:27
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.617 A=NA C2=0.426
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development