HsaINT0090847 @ hg19
Intron Retention
Gene
ENSG00000139624 | LASS5
Description
ceramide synthase 5 [Source:HGNC Symbol;Acc:23749]
Coordinates
chr12:50532350-50535893:-
Coord C1 exon
chr12:50535836-50535893
Coord A exon
chr12:50532401-50535835
Coord C2 exon
chr12:50532350-50532400
Length
3435 bp
Sequences
Splice sites
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
3' ss Seq
GATTATCTGTTTTCTCTTAGTCA
3' ss Score
6.87
Exon sequences
Seq C1 exon
GTGGAGATTCACATTTTATTTATGTATATTCTGCTATGGAATTAGATTTCTCTGGTCG
Seq A exon
GTGAGTCTTAACTTTCTCTAGTCCTCTGTTGGGTTCTAATCATGCCTAGATCTCTAGAAGTAAGAGTTAAATACCTTTAGATTTTTTTCTTTTCTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTTGCTCTGTCACCCAAGCTGGAGTGCAGTTGTGGAATCTCAGCTCACTTGCAACCTCTGCCTGTTGGGTTCAAGAGATTCTCTTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGTGCACATCACCATACCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGTGCCAGGATTTCAGGCATGAGCCACTGAGCCTGGCCTAAATACCTTTAGATCTTTATATTTCCCCCAACTTTTCCTCTGTGATGCCCACAGCCCAGGTTTATATCCTAATAGATTGTCTTCTGTCTGGGGCCTGACTTCAGTAACTTTATAACTTTACTGCTTCTCCCCTAGAAGATACTAATAATACTAGTAATAACTAAATCAGCATAATACTTAATGGTTTACAAAGCACTTGACAAAAATTGAAGGAGGAGAAATGGAATAAACCCTTTAAAGTGGGTGAAACAGGTATTATTCCTACTTTTTAGTTAATTGTCAGAATCAAAGAAGAATTTCAGGGGGCCAGGCACAGTGGCTCACACCTGTAATTTTAACACTTTGGGAGGCCAAGATGGGCAGATCATTTGAACCCAGGAGTTCAAGACCAACCTGGGCAACATGGTGAAACCCCGTCTCTACAAAAAGCTACAAAAATTAGCCTGGCGTGGTGGCGTGCACCTGTAGTCCCAGCTACTCAAGAGGCTAAGGTAGGAGAATCGCTTGAGCCCAGGAGGTCAAGGTTGCAGTGAGCCGTGATGGAGCCGCTACATTCCAACCTGGGTGACAGAGCAAGACTCTGCCTCAGAAAAAGAAGGAAGAAGAATTTTAGGCTTTTTGATTCTTTAGTTCATGTTTTTTTCCCCATACCATACTGTTTCTCTCTAAATGATATCATTGTGTTTTCAAAATATTATAGACAAAAAGCTGGCAGAACTAAAGGAAGAGAATAGACAAATATACAGTTGTATTTGAAGATTTTAATACTTTTCTCTCAGTAATTGACCTAAACCCTAGGCAAAAAAAAAAAAAAAATCACTAAGGGTGTAAAAGATATGAATGACATGATCAACCAGTTTTACCTTATTGACATTTATAAAACACTACACCAACAGCTGAAGAATACATATAATTTTCAAGTGCATGTAGAAAGATAAACTAATGCTGGGCCATAAAATAAGTCTCAGTAAATTTCAAAATATTGAAATCTTAAAGAATGTGTTCTCTGACCATAACGGAATTAAATTACAAGTCAATTGTAATGAGAGACATGGAAAACATTTGGAATTCGCCTGCATGAGGTTGCTCACACCTGTAATCCTAGCACTCTGGGAGGCTGAGGCAGGCAGGTTGCCTGAGTTCAGGAGTTCAAGACCAGCCTGGGCAACAGGGCAAAACTCTATCTCTACTAAAAATACAAAAAATTAGCCGGGCATGGTGGCACGTGCCTATAATCCCAACTGCTGGGGAGGCTGAGGCACGAGAATCGCTTGAACCTTGGAGGCAGAGGTTGCAATGAGCCAAAATCATGCCACTTCACTCCAGCCTGGGTCTCTGTCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAAATTTGGAAGTTAAACAACTCTTCTCAATAACCTGTGGATCAAATAAAAAATCACAAGAGAAGAAAATATTTTTAATTGAATCATGCTAAAAATCATATCAAAATTTCTGGGATACAGATAAAACATACTTAGAGGGAAATTTATAGCTTTAAATGTTTATATTACAAAAGGTTTAAAGTTGATCTAAATTTCTGCTTTAGGTTCTTGAAAAAGATAAGCAAAATAGGTTAAAGTAAGGAAATAATAAAAAATAAGCAGAAATTGGCCAGGCGTGGTGGCTCACCCCTGTACTCCCCTCACTTTGAGGCTAAGGTAGGAGGATCACTTAAGCCCAGGAGTTCGAGATCAGCTTGGGCAAGATGGCGAGATCCAGTCTCTATAGTGAGACCCCATTTCTAAAAAATGATAATAAAGTAAGTAAGTGGAAATTAATGTAATAGGCATTAGAAAAACAATGGATACATTTGTGGGGTTTTTGTTTGTTTGTTTGTCTGAGACAGAGTCTCACTCTGTCTCCCAGGCTGGAGTGCAGTGGTACAATCTCGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTGTCCTGCCTCAGCCTTCCTAGTAGCTGGGACTACAGGAATACGCCACCAGGCCCAGCTAATTTTTGTATTTTTGGTAGAGACAGATTTTCATCATGTTGCCGGGCTAATCTTGAACTCCTAACCTCAGGTGATCCTCCCACCTCGACCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCACGCCTGGCCTGTTTTGTTTTGTTTTGTTTTGTTTTTTAAAGACAGGGTCTTACTCTGTCACCCAGGCTGAAGTGCAGTTGCGTGATCACAGCTCACTGCAGCCTCAACTTCCCAGGCTCAGGCAATGCTACCACCTCAGCCTCCCAGGAAACTTGGGACTACAGGCATGTGCACAACCACACCGGGCTAATTTTTGTATTTTTTGTAGAGATGGGGTTTTACTCTGTTGCCCAAGTTGGTCTTGAACTCCTGGGCTCAAGCAATCCACCCACCTCACCCTCCCAAAGTGCTAGGATTAACAGGTGTGAGCTACTGTGCCTGGCCATGGATAAAATTAATAAAGCCAAAAGTTCATTCTTTGAAAGGTTTGATTAAAATTGACCAACTCCAACAAAAAAAGGAAATATGAATTATCAATATGGAAAGGGTTATCACTACAGATCCTATAGTCATTGAAAGGATAATAAGACAGTATTATGAACAATTTAATGATAAGAAATCCAGCAGCAAAGATGATGTAGACAAACTCCTTAAAGGACATAATCATTATTCCATTAGAGATGATTACTTTTGACTTCTGAACATGGCATGGAGATATCTTTCTTGGTTATCAAATGAATCATTGTCTTCCTGTATATATATTCCAGGTAGTGATATTTCCTAAAACTAGCCTAAAGCTCTCACTGTTCTTATTTACCTCAAAGCATTGTTTTTCTATTTATAACATTCTGTTGTAGAAGAACAGTCTAGCTATTTATTGATCCTTTAGGGAGCCCTAAAATCTGTTTGGGGGCTTTTCTGTCCTCTTTTGCCCCAGCCTAGAGAGAAGGGGATTATATGAGGTAGATCTTGAAGCCAGGTGAGAATCTTGAGGACTGACATGGATTATCTGTTTTCTCTTAG
Seq C2 exon
TCACCTTGGTTCTGGGACATCCGACAGTGCTGGCATAACTATCCATTTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139624-LASS5:NM_147190:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0379811=TRAM_LAG1_CLN8=PU(9.6=92.9)
A:
NA
C2:
PF0379811=TRAM_LAG1_CLN8=PU(14.9=77.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)