HsaINT0095572 @ hg38
Intron Retention
Gene
ENSG00000134013 | LOXL2
Description
lysyl oxidase like 2 [Source:HGNC Symbol;Acc:HGNC:6666]
Coordinates
chr8:23333401-23341203:-
Coord C1 exon
chr8:23340992-23341203
Coord A exon
chr8:23333624-23340991
Coord C2 exon
chr8:23333401-23333623
Length
7368 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGA
5' ss Score
7.61
3' ss Seq
TCCCCTCCCATCGTCTGCAGAAT
3' ss Score
10.66
Exon sequences
Seq C1 exon
AACCTGAATATCCAGGTGGAGGACATTCGGATTCGAGCCATCCTCTCAACCTACCGCAAGCGCACCCCAGTGATGGAGGGCTACGTGGAGGTGAAGGAGGGCAAGACCTGGAAGCAGATCTGTGACAAGCACTGGACGGCCAAGAATTCCCGCGTGGTCTGCGGCATGTTTGGCTTCCCTGGGGAGAGGACATACAATACCAAAGTGTACAA
Seq A exon
GTAAGAGGACTGCACCAAAGGGGTGGCTTTGAGGGTATCCGCCCTGCCTAAAAGAGTTAAAAGTGTCCGCCCTGGTGGTGGCCTTTCCTTGGCCAGGCATGGCCAGGCAAGCTGGTGTCCCTGCAGGCAGCCTGCACAGAGCCCCTGGGCCGGGCCAGGCGCCAAGTTCAAGGGTGCCCCGTGGCATCCTTACCCTTAAGGAACTCACACATCTACAGGAGATAGACCCTAATCCCTAGAGTAGCTTGTGGGAAGGCGTATTGCAGAAGTGAGATGCAAGCTGCCCCCAGCCCAGAGAACCCCAGCTCAGGGTGCTGCCGGCCAGCTCAGGGACTGCACGAGCTAGGCTAGGGCAATACCCTGGCCAGGCTGGGCACAGACAACACCAACTTAAGAAGAAATATTTACTTGCTCTTGGCAAATGATTCTTCTGAGAAATCTGGAAGTTGCAGCAGGTAATTGAGACACTGGTCCGTGCAGTTCACTTCATCCAATCCCAGTTAAATCTGACAATACTGTGATGATCGCTAAGGTTAATATTTCCCAGTAGGGGAAAGAAGTAGACAGGGACAGAACCTGGAGTCATTTTGACTTAAGGGGTGTCCAGTGGAAGGATTCCAGCACCCCAACAAGCTGATGGCTGGCGTATACTTGGGGTATACTTGGTTGGTCATGGGGTGTTCCTCCCTCCTCTTAATAATGATAGGAATACTGGCTTGGCTTTACCAAAGACTTATAATGTGCCAGGCACTATTCTCAGTCATTTAATCCTCGCACCACCACTGGGAAATAGGAGTCTGTTTTAGAGTTGAGTAAACTGGAGAAAGGTGATAGAACCAGGAAGGGGCAGATCCAGGCCTCACGCACACCCTGGCCTCTGGAGGTCCCCTGTGTCCAGCTATAGGGTCCACACTCTTAGAGGGTGCAGACTCACAGCACTGTCTCTTTCCTTCCAAATCAGAGGAAGAAAAGATGTGGCTTCCATGTCAGGAGACCTGGCTTGAAGCCCCAGCTGTACCCACCAGCTCCCTGGGGTGCCGGGCAGACCACATATCCCTCCCTGATCCTGGCCCAGCCCTGCCTGGACGGGGTGGGCCATAATTTTGTCCCAGCCCCCAGCCCCTCACATGGGTGGGTCAGTGCAGCTGCAGAGCTGCCCATTTGGGTGAGCACACAACACCCCAGGCTGGCCATGATGGTGATTCCAGTCCCCAGACATGGCCCAGACCTTCCTGTTGGCACCAGGAGTCGCCGTCCTCTGAATACTTTGGAGAACTCCCACCCGACTCCTTCCTTGGTGATACCTTCTCAGCTTTTCTTACCAGTCGGAGCCAAGAAAAGCAAACCCCCTCCCTGGCAGGCTTCCTACCTGGCTGGCCCTACCAGTGCCCCCAGCCTGGCTGCTGTTCTAAGCTGGACAGCACGCGCCTTGTTCAGATGGCGTTTGGAAGCCATCTCCCAACCGTGGCCAGTCCAGAGTCCTTCTCGGCTTTTGAGGAGTTGATCTCAGGCCAGTTTCGGCAGCTGGGCCCTGGGTAATCCTGTCACGTGCTGGATTGGAACCCCCATCCTGCCCCTCCCACCCTCTCGTCTGTGGCTTTGCCTTTTCAAGGACGGGGAGGATAAGGCTTCCAAGGCTGAGAGCGATCCAAGGAGGGGGTGGTGGGTGGTGCTGTCTGCAGGATGGGTGATGAAGAACAGAAGCTGCTGGAAACCAGCCCCTCCTGCAGCCTTCTAGCTGGAGAGGTGGGGCTGCCTTCCTAGCAGAGGAGTGGGAAGGGAAGCACGACCTTCTCAGCTTGGCCCTGTCATTTTGTGTTCGTCTCTGGGACTCAGTTGACAGTTAGGCCTACATGTGTCCCAAAGAGAAAGGTGCTGGGAAGGCTTTCTGTGCCTCGGTGGGCTGTCGGGGCTGAGCTGCCAGCAAAGGGCTAGGACTCCTAGGGAATGATAAGGCTCAGAGACCACTGGCCTAAGCCCTGGGTCTGCCTGGAAGAGAACATGGAAGAGGCCTGAAGGGCAGTGGACTCAGGGTGTCACAGCCCACACCCAGCAGAGCCTGCAGGACAGCCCAGGTCTGCTTCAGGGAGAGCACCACCCAGCAGTCTCCACCTGCTGGCCCTGCTGCAGCTCCTCTTCTCCCGGGGGTAGGGCCAGCTCAGAAGCTCTGGCCAGTCTGAGGGTTGTGGCAGGACTGGCCTGGGACTAGGGATATCCATGGGCGCTGCTCAGAAGCTGAGGACTGCAGAGGTCTGGAAGGCAGACTGAGGACCACCACCCTGCCCGGCCCTTGAAGCAGTGGCTTGCAGTTGCATCTTTCCCATGTCCCTTTCCCTCTTCCTACAGCCTGTGGCTGCTGTTGCTGGCAGCACACCTCTGAGGCCCAAGAAGGGACCCCCTTCCCTCCCGCCATGCAGCACTGCCCACTCTGCAGGAAATTATTTTCAAAGTAATTCCCAGTCTGGGGTGGAGTTAGTAATCTCCATGTATCCACCAAGGCCCGTGAAGGACCTTATAGCCTCGGAAGCTCACCTGCTTAACCCCCGAGGGCCCCCCACCTTGGGCCCCCCCACCCCGCTGCTGCCTTACTGGACTGGCTCCCTCTGTGAACCTGCTGGGCTGGTGGCCACTCGGAAGCCTGAGAGCTGCCCCCTGGCCACCAACTGCAGCTCTTCCTCAGCACCTCTGCTTCCCCTAGTGATACGGTTTGGCTGTGTCCCCACCCAAATCTCATCTTGAATTGTGGCTCCCATAACCCCACATGTCGTGGGAGGGACCCAGTGGGAGGTAACTGAATCATGGGTGTGGGTTTTTCCCATGCTGTTCTCATGATAGTGAATAAGTCTCATGAGACCTGATGGTTTTATAAAGGCCAGTTCCCCTGCACACGCTCTCTTGCCTGCTGTCATGTAAGACGTGCCTTTGTTCCTCCTTCACCTTCTGCCATGATGGTGAGGCTTCCCCAGTCACGTGAAACTGTTGAGCTTATTGAACCTCTTTCCTTTATAAATTACCCAGGCTCGGGTATGTCTTTATTAGCAGCATGAGAATGGACTAATACCCTCCAGTTACCTGCACATACCCCAGAGGTCTCTGCAGCCACAGGCTTGCCAAAAGTAGAGTCAGGGGCTCCTCACCAAGGCCTGCTCTCTGATTGGTGTGGCCGTGGCACTGACTTCCACACCGGGCTGGGGTGCAATGCATGTACCTTAAAGCTAATGAAGCTTAAACTTCAGGCCCCCATTCCTGGTGCCAAGAGGGAGCATTTTGTAGTCATAATTTTGTTCTCCCAAAAGTAGGATCCCAATACTGACATCATTTAATTGAAATGAGCTCTCTAAGCAGAGATTCTGCATTTAATGTTGCAGCTGAGGAAGTTAGAAAGGCCTCCAGCGGTTTGCCTGGTTGGTTGGCTGAAATGTGGACCAAAGTGTGGCCCACAGTGAGTGAGTAGAAATGCTGACCCTGCCTCTGTTGTGTGTAGAGGACAGAATTCAAAAGCTTAGGGAGGTTGGATGTTAGAGTGGATCTTACCTTTAAGACCTCCTCACCCACGCTGGGAAGCTCCTGAAGACATGCCTTTCACCTTGATGGTGAGAAGTAAATATATGAAAGGAGCTCCAGCCTCCTTGAGGAGCTGTGATCACTCTTCTCTGAAGGCCAGACCTCACAGCAGGAACAGCAGCCACTGAACCAGTAACCTGAATGCGACCGGAGTAATTGGCTCCAGGGTGGCGGGGGCCCCGTGGCTGTAGTACTACCAAAGGCAAGGTGGACGTGCTGACCCTATTGGACAGTGGAGTCAAAGCAGAAATCAGTCTGACTGCTGCAGACCTGTGGTGTTGGCTGGTTGATCATGATGTTCCTCGAAGTGAAATAGACAGGAAGCCTACTAAGTTCGTACTTAATCTGTATAAGCAGAAAACTTCTAGGTCAAGCAAACAAAAGTCTATCCCAAATCATAAAAGCAGAGTAGAGTCATGACCCCTCAATCCATTCCCGTACTTGAGCCAGTTTTATCAGACTGGAAGCTCTTGAATGAGGGAAAGGCTGGGTACCCTCAAGGAAGCACCCTCGTAGCCTGCCAGAAATCTATACTGTATTCTTTCTCCCAGTTCTCCAAAGACACCTTTCACCAGGATGAGCGTGCATTGGAGAAAAGGAAATAATCAGATCTTTTGGACTACTGGCCACTGGTTCTGAGCTGACAGTAATTCTAGGAGACCCAGAACATCAAAGTGGGGGCTTATGGGTTTTTAGCTTACGTCCATCTGAAACCCATTCTGTGCTATTTCCCCACTTCCGGAAAGCATCATGGAAATAGATGTACTCAGCAGCTGGCAGAATCCCACGGCATCTGCCTTCACTCTTGGCAAGGGGAGCACCGGTCGGTAGGACTCTTGGTTGAATCAGTCCAGCTCCGTGTTCTTCCTACAGTCCAGCTATTGGCCTAGCTGCCTCTTTCACAGGCAGGCTTCCCGCTCCACTCCACTCAAGGCTGCCTCACTCACTCCAGTCACTCCTCCAGTCTCCAGGTCTGGAGCGGGGTGGGCTGTCTTCCACCCTCCGTGGGCCTCCGTCTGCAGCTCAGAGGCCTGTCCCCAGTGAAACACTGGGATGGAGGAGGGGAGGGGAGGGTATCCCCTGGGAGGCCTGAACGTGCTAGAGGGTCTGCAGCACATTCCTGGGGGCTGATGTCAGAGGGATCCGGGCTGCTGGGGACAGTTGTTTGCTGTGGGCTCTGCACTCTTCATTTAGAACGCAGGACATCTGTTCCTGGAGAGGGTGGCGCTCACTGACGGCTGGAAGCAGAGGGGTTTTCCTGAGCCAAGGCAGGCGGTGAGGTCTGACCAATCCTCGAGCAGCTGGTGTTCCCCCGAGTATCTTCTCCCGCCCCTGTGTGGGCGTCATGGAACATGCTGTAAGCTTCCAAGTGCAGGGGCCTTGCAGGAAGTGTGTCTGGAGGGCAGTGGTTCCTGGAATTATTAATAGCCCTCCTGAGCAGTTCTCTGCCCTGGGCTGCCGCTGTGGTGAGCACGCACCCTGAATTTGCCAGGATAGTCCTCAGCAAGATTCCGTGTCATTGTGTTCACAAGCACACTAGAATTGTAACAAGTCTCAGATTTGGGTTAAGGAGAGATGATAACTGTGTCTGTAGGATTTGCCCTTCCTCTGTCTTCACACCCCATTCACTCTGAGACAAAGGAGGTACTTCCAGGGCTGCTGGACCAGCAGGGATGGGACCTCGCCTCTGCCCTGTCTTGGGGTCAGCCTGCCCAGCGAGTACCCTCTGCTGGCTCCTTCTGGCATCTTACTGGGTCCTGCCGTGCAGGGACAAGCACACGGGCCCTGAAAAGCTGGGTCGACATGAGCAGGTAGCAGGGCCTTCCTGGACCTCCTTTGTTTCAGATCCCACCATCATTCAGGGCCCAATTTAAAGGCTTCTCTTCCGTAAAGTCTCCCATCACTCCAACCATGGAATCCCTCCCTCCTGTCACTCTTCTTTTTTTTTCTTTAACAAATACAGTTTTATTTATTTACTTATTTATTTCACAAACTCTTATGTAGCTCTTCCTATCTCTGGGCACTGTTTTAAGTGACAAGTATTAACTCATTTAAACTGTCACAACAGGCCAGGCACTGACGCATGCCTATAATCCCAGCACTTTGGGAGGCAGAGGTGGCCAGATCACCAGAGGTCAGGACTTCGAGACCACCCTGGTCCCAGGAGACCTCAACTTCTCCAGAGTTCTAGCCTCTTCTTAAAGGGCCAGAGTCATGGGAACCCAGATGGGGTGAGGGGGTCTCCTGCCACGGCCTCCTTACAATGATATGACTTGGCATAAATTTGGATACTACCTCCAAATACAGATTTATGGTCTGGCGTGATAGCTCATCCCTGTAATCCCAACGCTTTGGGAGGCCGAGGGAGGCAGATTACCTGAGGTCAGGAGTTCGAGAGCAGCCTGGCAACACGGTGAAACACTGTCTCTACTAAAAATACAAAATTAGCCGGATGTGGTGGCAGGTACCTGTAATCCCAGCTACACGGGAGGCTGAAGCAGGAGAATTCCTTGAACCTGGGAGGTGGAGGTTGCAGTGAGTTAAGATCGCGCCAAAGCACTCCAGCCTGGGCAACAGAGTGAGACTCCATCTCAAAAAAAAAAAAACAACAACAAATAAATAAACTGTCACAATAATCTAGTGAAGCAGATACTACTTCTGATTTTGGACATGAGAAACTGAGGTACAGTATCCTTTTTGGTAGCCAATCTATTACTTATCAGTTGGTTACTGTTTTAGAAAAAAAAAAACTGAATTACCTGCATCTATATTCTGCCTTTAAAAAAAAACATACAAAGGAACACTTTGCACATGTTAACAATACAGGCTAAGGGCTTCCTTAGGATATGGTACAGAGACAAGCTCAACCTCACTGATCTTCCTGGGTGCAGGAAGCAGTAGTTGCATTACCATTATAATTTCTATTGCTAGGCAGATTGTACTTTGATTCAGCAGATGGAGTAATTTAAGACTGTTTTCATTGTTTCTCATTGGAAATACAAATTTAATCTTGTATATCGTTGGGAGAGTTTAGCAATCAGCTTGTACTGCTCATTGACAAAGAAAAATAAAGCTAAAGAATGACAACAGGCTGGGCACAGTGGCCCATGCCTATAATCCCAGCACTTTGGGAGGCCGAGGCAGGCAGATCATTTGAGATCAGGAGTTTGAGACCATCCTGGCCAACATGGCGAAACCCCGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCAGGTACCTGTAGTCCCAGCTACTCAGGAGGCTGAGGCTGCAGAATTGCTTGAATCTGGGAGGCAGAGGTTGCAGTGATTGCACCACTGCACTTCTGCCTGGGGGAATAGAGTGAGACTCTGTCTCAGAAAAAAAAAAGAATGACAACAAATTTTGTTGGAATTATCTGAAGAGTTAGGGTAAACATGGTTTACCTTCGACTGTGAGGGGTTTTCTAGGACCAGGGATCTCACCTGTTTTAAATACCTTTGTGCATTCTGTGTTCCTGGGCTTTATTATTATTATTTCACCACATTGAGTGAGTCCTTTCTTTCCTAGAATGGAAGCTGCCTGAGGGCAGGAGGCCTTGTCCACCCTCTGCGTCCTGTCCCCCAGTGCCTAGTGTGGTGCAGGCATTAGCAGGTGCTCAGTGAATGCTGGCAGAATGGACTGAGCTGGGACCCTCTGTGAAGCAGGGCTGAGCTCCAGGAGCAGGGCCCAGTCTCTCATGTTCTGCCTCGTTGCAGAAGGAATCGGGGTAGGCGTCATGATGCCCTGGTCCCCTGTCCCCTCCCATCGTCTGCAG
Seq C2 exon
AATGTTTGCCTCACGGAGGAAGCAGCGCTACTGGCCATTCTCCATGGACTGCACCGGCACAGAGGCCCACATCTCCAGCTGCAAGCTGGGCCCCCAGGTGTCACTGGACCCCATGAAGAATGTCACCTGCGAGAATGGGCTACCGGCCGTGGTGAGTTGTGTGCCTGGGCAGGTCTTCAGCCCTGACGGACCCTCAAGATTCCGGAAAGCGTACAAGCCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000134013:ENST00000389131:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.037
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PU(48.1=71.8)
A:
NA
C2:
PF0053013=SRCR=PD(50.9=72.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development