HsaINT0096519 @ hg38
Intron Retention
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68433602-68436999:+
Coord C1 exon
chr11:68433602-68433838
Coord A exon
chr11:68433839-68436888
Coord C2 exon
chr11:68436889-68436999
Length
3050 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGG
5' ss Score
9.2
3' ss Seq
TGCATGGCCTCTCCTTGCAGCCA
3' ss Score
9.45
Exon sequences
Seq C1 exon
AGCCGCCCACCTGCTCCCCGGACCAGTTTGCATGTGCCACAGGGGAGATCGACTGTATCCCCGGGGCCTGGCGCTGTGACGGCTTTCCCGAGTGCGATGACCAGAGCGACGAGGAGGGCTGCCCCGTGTGCTCCGCCGCCCAGTTCCCCTGCGCGCGGGGTCAGTGTGTGGACCTGCGCCTGCGCTGCGACGGCGAGGCAGACTGTCAGGACCGCTCAGACGAGGCGGACTGTGACG
Seq A exon
GTGAGGCCCTCCCCGTCAAGGCTCTGCCAAGACCCTGGCCCTGCCCTCCGGGATACGAGCTTGGGGCTGCCTCCGGCCTCACAGGAGTAGGGGCTCTGAAAACCTTTGCTTGCAGGGAGATTGCCAAGTCTGTCTTTTAGGCCCAACAAGGAAAACTCTGCAGTTCCACCCATCCTGTCCCACCAGGTAGTGTGGCTTGAAGGCAGACTGTGAGGGTCTATCTCACCTTCCTGCATTAGGTCAGGAGTTTCACAGAAACCTGAGGCACATTCAGGGGTGGGCTGCAGAGGTCCATGGCTCACACCCTGGAAAATCCGCCCCCAAAAGACAGTGCTGTCTCCACTGACCAGTCTGTGGGATAGTGCTTAAGCCTGAGTGGTTTCTATCAACATGTAGAATCAGGAGGTATAAAGAGATTTGCTCAGGCATCCTGGGCCCTCTCTGACCAGCAGGATCTTCCTTTAGATCTTGACAGTGAAACACATCTCTTCTGTGCCCCCTGTGAGTTTTCTTTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCATTCGAGACAGAGTCTTGCTCTGTCACCCAGGCTGGAGTGCCCTGGTGTAATCTCGGCTCACTGCAACCTCTGCCTCCAGGGTTCAATCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATGACAGGTGCGCACCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCCGCCCGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCGCGCCCGGCCTGAGTTTTCCTTTTATGAAGGACCTGCTTGGTTGGTTGCCTGCCACATGTTGTCAGCACCATGGGCCCAGGACTGCTGAGGAGCTGTTGATGCCCTCGCTCTCCCAGAGCCACCGGCTCTGTTAGATAATTCACATGCAGTCTGGCCACTGTCCTACGTCCTCATTCACAAAGAGCAGACATTTCGTAGAAGATGAGGGCCTGGGAGTAACCTCCCTGCATGTTTTTCTATAAAGGCATAGTGGTTAAGTCCTTCCAGCTCATTGACCATTGGAGAATTTTATGGAGGCTGTAGACTAGGGGCTGGTAAACTAAGGGCCCAGGGGCCAAATCCAGCCTGCCACCTACTTTTGTAAATAAAGTTTTCTTGGTGCACAGCCATGCCCATTCATTCATTTGCACAATGTCTGTGGCTGCTTTCATGCCAAAAGCAAGAGAACTGAGTGGTTATGCTGGAGACCTACGGCCTTCAAAGCCCCAGACCTCACGTCTGGCCCTTGACAGACAGAGCTTCCCCAGCCCTGCTGCGCATCCTGGCCCAGCATGTGCTGTGTGTGTGATTTCAGCTTGCAGGAGCCGTGGTTAGGAATTGTCCCTGTGTTGGTCCATTTTGCATTGCTATGAAGGAGCACCTGAGGCCGGGTAGATTATGAAGGAAAGAGGTCTGTCTGGCTCATGGTTCTGTAGGCAGCACCAGTATGGCACCCGCATCTGCTCAGCTTCTAGTGAGGTCTCAGGAAGCTTTGACTCATGGTGAAAGTCGAAGCGGGAGCAGGTGCATCACATGGTGAGAGAGGGAGCAACGGAGAGAGAGAGAGAGCGCCTCTCCCTCTTGCCCTCACCTTGAGAGGAGATGCCAGGCTCCTTTAAGTAACCAGCTCCCATGTGAACTCACAGTGAGAGCCCATTTGCTACTGCGGAGAGGGCACCAGGCATCTGCTCCCATGACCCAAACACTGCCCACCAGGCCCTACCTCCAACCTTGGGGTCATATTTTATTCTGTTCTATGCTATGCTATGCTATGCCATGCCATGCCATGCCATGCTATTCCTATTCTATTATTTGAGACAGAATCTCGCTCTGTTGCCCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGCGATTCTCCTGTATCAGCCTCCCGAGTAGCTGGGATTACAGGCACACACCACCACACCCGGCTAATTTTTGTATTTTCAATAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGGCCTCAAGTGATCCACCTACCTCGGCCTCCCAAAGTGCCATGATTACAGATGTGAGTCACTGCGCCCAGTGAGGGTCACATTTCCGTTGAGATTTGGAGGGGCAGACGTTGGAGCCATCTGAGCCCCCTCGTCCCGCTCTAGCTTCTCCTCCCGTGTGCCCCGCGGTGCTGGTGGCAGGCCCTTACGCCGGTTCTGGCTGCATGCTCTGTTCCAGAAGCTTTCTTCCCTGCTTGGTTACCAGAAAATCATCCCATCCATTACAAGGACAGGGTCCCCTTATCTCCCATTCCCAGGGCAGGACACCGGGGGCAGGGCAGGTGGGGAACTGAGCAAGTTCTCTGGGGGCAGGCGTGGCTATGGCTCCCTCTGGGTGGGCGTCTGGGGAGGGGTGGAGGCAGCCGTCAGCGCCCTGGCTTGCTCTTCCTCCCTGGCCAGAGACTGTGGCCTTGTGCTGCTCCCGTGTGGGCTGCCTGCACCTCCAGTGGGTTGTGCTCCCTCCCCTCCCCTCCCCTCAAGCTCTGCTGAGCACCACTGCCTTCCACAGCCCCCACTCTCGGGAGGCGAGGCTCCTCGTGGCCATTCCTGTCCTTGGCACCCACCCCCCCACCAACCTGGTAGAGCCTTGGGCGGGGTCTGTTACTCCTTGCATGGCGTAGACCTCCCCACAGTAGGCACCTGACACATACCTCCTGGGGGGCAGGCAGGAGGTGCGTTGAGGTCTCAGCCCTGGCAGTCCCTCCCCTGCGTGGCATAGGCCTCGCCACAGGGTCATCGAGGGTGGGTGGAGACTGTACTAGACCACTCCCCGCTGGTCCTAGAAAGGGTCCCATCTGTCTGCTCTCTGTTTGGAGTCCAGACCTTGGTTGCTGTGCCCTGCATGGTGGGCTGGGGGGCACCCTCCAGCCTCTCTGAGTGCATGGCCTCTCCTTGCAG
Seq C2 exon
CCATCTGCCTGCCCAACCAGTTCCGGTGTGCGAGCGGCCAGTGTGTCCTCATCAAACAGCAGTGCGACTCCTTCCCCGACTGTATCGACGGCTCCGACGAGCTCATGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337:ENST00000294304:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=48.8),PF0005713=Ldl_recept_a=WD(100=46.2),PF0005713=Ldl_recept_a=PU(0.1=0.0)
A:
NA
C2:
PF0005713=Ldl_recept_a=WD(100=97.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development