MmuINT0092712 @ mm10
Intron Retention
Gene
ENSMUSG00000024913 | Lrp5
Description
low density lipoprotein receptor-related protein 5 [Source:MGI Symbol;Acc:MGI:1278315]
Coordinates
chr19:3593516-3597480:-
Coord C1 exon
chr19:3597244-3597480
Coord A exon
chr19:3593627-3597243
Coord C2 exon
chr19:3593516-3593626
Length
3617 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGG
5' ss Score
7.61
3' ss Seq
CCGCCCCTTTCTCCCCACAGCTG
3' ss Score
12.63
Exon sequences
Seq C1 exon
AGCCTCCTACCTGCTCCCCTGATCAGTTTGCATGTACCACTGGTGAGATCGACTGCATCCCCGGAGCCTGGCGCTGTGACGGCTTCCCTGAGTGTGCTGACCAGAGTGATGAAGAAGGCTGCCCAGTGTGCTCCGCCTCTCAGTTCCCCTGCGCTCGAGGCCAGTGTGTGGACCTGCGGTTACGCTGCGACGGTGAGGCCGACTGCCAGGATCGCTCTGATGAAGCTAACTGCGATG
Seq A exon
GTGAGGCCCTACCCTGGCTGCCATCTCCCTCCCAGGTCCCATTAAAGCCATTTGTCCTTCCTTCCTATACATCAAACACGGGGCTCCATTTTGCCTTCCACAGGTAAGGGTGCTAGAAAACAGCTAAATTGGCAGGCCGTCTTGGTGGGAACAAATGAAGTAAGTTTTAGGCACAGCCTGAAGGAATGCTCCTGCATGACCCCATCTATTCTTCGGGCAGTTGACTTAAAGACAGGCTGAGACTCACATTTCCACATTTGGTAGTGACTTCTGCAGAAATGTAAGATAAATCCATTAGTCAGTTGCTTTCAGGGCTCACACCCGGTACAGTGTCATCTTCAAAGGCAGTGCCACACTCACTGCATTGTGCCATCTGTGGGATAATGCTGGCCACCTGGGACCACTCTGACTGACCACGTGTGTCCCGTCGTCCTGTCCCCGTCCCCGTTCCCCGTCCCCGTCCCCGTCCCCCCGCTTTTGAGATAGGGCTTTATATAGCCTGGGCTAACCTTGAGTTTGCTATGTATCTATAGTCTTGAACTTATTCTTTTTCTACTTCCTACATGCTAGGATTATAGGTATATATTATCAGTGTGATATGTAGAGGATCAAACCCAAGGCTCCTAAATGCTATGCAAGCACTCTGTGCTTATCAACCTAGCTACATTCTTACCCTCCCTCCCTCCCTCCCTCTCTCTCTCTCTCTTTCTGTTTTTTGGATTTTTTTCCCCCTGAGACAAGGGTTTCTCCATATAGCCCTGGCTGTCCTGAAACAATAGACCAGGCTAGCCTTGAATTCTGTCTGCCTCTGCCTCTGCCTCCTGAGTGCTGAGATTAATGGTGCATCACCACCACCTGGCCCTCACCCTTATCTTGAGATTGTGTGTGACTCTGTGTGTGTGACTGTGTATGTGTGTGTGTGTGTGTAAGACTCTGTGTGTGTGTGACTCTGTGTATGTGTGATTCTGTATGTGTGTGTGACTCTGTGTGTGTGATTCTGTGTGTGTGTGTGGTGTGTGACTGTGTGTATGTGTGTGTGACTCTGTGTGTGTGATTCTGTGTGTGTGTGTGTGTGTGACTCTGTGTGTGTGTATGTGACTCTGTGTGTATGTGTGTGTGATTCTGTGTGTGTGGCTCTGTGACTCTGTGTGTGTATGTGACTGTGTGTGTGTGTGTGACTGTGTGTGTGTGTGTGACTCTGTGTGTGTGTGTGTCTCTGTGTGTGTGTGTGACTCTGTGTGTTTGTGTGTGTATGTGACTCTGTGTGTATGTGTGTGTGATTCTGTGTGTGTGGCTCTGTGATTCTGTGTGTGTGTGTGACTCTGTGTGTCTGTGTGTGTGTGTGTGTGACTCTGTGTGTATGGTGTGTGACTCTGTGTGTGCGTGTGACTCTATGTGTGTGTGTGTGACTGTGTGTGTGTGACGCTCTGTGTGTGTAACTCTGTGTGTGTCTGTGACTCTGTGTGTGTGTATGTGTGTGATTCTGTGTGGCCTTGGCAGGTTTCTCTGTGAAGCCATGATGATTGCTTTGCGTGCACACACACACACATACACACACATGCACACATGCAGTTATACTCTTTTTTTTTTAAAGATTTATTTATTTAGTATATGTAAGTACACTGTAGTTGTCTTCAGACACCCCAGAAGAGGGCGTCAGATCTCATTATGGATGGTTGTGAGCCACCATGTGGTTGTTGGGATTTGAACTCTGGACCTTCAGAAGAGCAGTCTGGTGCTCTTACCCACTGAGCCATCTCACCAGCCTGCACTTATACTCTCAAGACATCTTTTTTTAAAGACTTGTTTATTATATATAAGCACACTGTAGCTGTCTTCAGACACTCCAGAAGAGGGCATCTGATCTCATTACAGATGGTTGTGAGCCACCATGTGGTCGCTGGGATTTGAACTCAGGACCTTTGGTAGAGCTGTCAATGCTCTTAACTGCTGAGGCATCTTTCCAGCCCCCAAGGCATCTTTATCCACTAAGTCAGTGGTTCTCAACCTTCCTGGTGCTGTGACCCTTAATACAGTTCCTCATGTTGTGGTGACTCCAAACCATAACATGTATTTTGTTGCTAGTACATAACTGTAATTTTGTTGCTGTTATGAATCATCTGATATGCAAGATGCCCTACGTGTGACCCTGCCAGAGGGTCTTTTGACACCCTCTCCCCCAAGAGGCTGTGAGACCCACAGTTTGAGAACTGCCGCATTAAGCCATCTCGCTGGCCAGCCTTTAATTAACATTTTTTAAAATTTCCATTTTATGTGTATGGGTGTTTTGCCTGAATGTGTGTATGTGTAGCACGTGCATGCCTGGTGCTGGCAGAGGCCAGAAAAGGGTGTTGGATTGCCTGGAGCCTGAGTTACAGATGCTTGTAAGGCGCCATGTGGGTGCTGGGAACTGAGCCCAGGTCCTCTGGAAGAGTAGCCCTTGTCTCCTAAGTGCTGACATGTCTCCAGCCCTCCCTGAACCTCTCTTAGCGTTTGCTGTGTGTGTCGCTCTAGTGCCTGATCCACACTGAACTCTGTCACAGGCCACATGTTTTCAGCACCATAGACCCAGGCTGGCACTGAGCTGCTCCTGTGGCATTCTTGCTGTCTCTGCCCGAAGCTGCTGGGTTATGCTTTCAATGACTCAGATGCTGGCTGCCACTTTCCTGCATCCCCATTCAGCATGACCCCACGTTCTGCAGGGGACAAGGCCTGGAGTGGCCTTGGCAGGTTTCTCTGTGAAGCCATGATGATTGCTTTGCAGCTCACCAGTGCTCTGAGGGATCTGGTGGAAGCCACGATAACGGCACATGTGCCCAAACCAGTTTGCTGCCAATGTCTGTAAATAAAGGTACATTGTCTGTGCCAGGCCCAGTGGTTCCTGTACATGTGGGCCACTCTCAGGCTAGACGAGAGCTGGGTGGTTGGTTACAGAGCCAGCAATGTCTGCTTCTGGTCTCAGAGTATCATATGTGATCAGTTTAGAAATCCTCCCTCATCCCACTCACCTGCTCACCCTCTTCACCACTGACAGCAGGTGCTGGCCCTCCACTTCTAGGAAGGACAGAGTGCCCTTGTCTCCTGTTCCCAGGTCAGCACCTGGAGCATGTCAGGAGAGGGTCCAGATGGATGGTTGTGAGAGGATGTTAAGTCCCCAGATGCTTCCTCAGAGGGCCGCAGTCTGCAGATTTGTTTGCCCACTCTCTCCCAGGTGTTAGAGGAGATAACCTTGGTCTCTACAAATGCAGCACCTACTTCCATGGAGTTCTGGGCTCCACTGACCCAGCCTGCACTGAGGAAATGGCGTTGTTGCCGACTCCACCTTCCTGGAAATCCTGCTTGATCCTGGAGCTGAGGCTACTGCTCTGTGCTGTCTCTGACTCAGGCTGCATGCCTCCTGGGCACAGGCTGGGCATCAAGGTCTCTGTGCCCTTTGGCATTGAACAGAGCTTCAGGGATCATTTTAAGGAGACTGGATTTTCCATGATCTTTTCTAGCTGGGTCCTAGAAAGTATTCCTGCTACTGGGTCTGTATTTGGAATCAGACCTTTTCGGTTGGAGCCAGGCAAAACTGCTGCTCTCTGGCTCCTCTGAGCACCGCCCCTTTCTCCCCACAG
Seq C2 exon
CTGTCTGTCTGCCCAATCAGTTCCGGTGCACCAGCGGCCAGTGTGTCCTCATCAAGCAACAGTGTGACTCCTTCCCCGACTGTGCTGATGGGTCTGATGAGCTCATGTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000024913:ENSMUST00000025856:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005713=Ldl_recept_a=WD(100=48.8),PF0005713=Ldl_recept_a=WD(100=46.2),PF0005713=Ldl_recept_a=PU(0.1=0.0)
A:
NA
C2:
PF0005713=Ldl_recept_a=WD(100=33.9),PF0005713=Ldl_recept_a=WD(100=32.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types