HsaINT0096522 @ hg38
Intron Retention
Gene
ENSG00000162337 | LRP5
Description
LDL receptor related protein 5 [Source:HGNC Symbol;Acc:HGNC:6697]
Coordinates
chr11:68438446-68439916:+
Coord C1 exon
chr11:68438446-68438682
Coord A exon
chr11:68438683-68439776
Coord C2 exon
chr11:68439777-68439916
Length
1094 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
CCCCGTCCCTTCCCTGCCAGGCA
3' ss Score
9.89
Exon sequences
Seq C1 exon
AAATCACCAAGCCGCCCTCAGACGACAGCCCGGCCCACAGCAGTGCCATCGGGCCCGTCATTGGCATCATCCTCTCTCTCTTCGTCATGGGTGGTGTCTATTTTGTGTGCCAGCGCGTGGTGTGCCAGCGCTATGCGGGGGCCAACGGGCCCTTCCCGCACGAGTATGTCAGCGGGACCCCGCACGTGCCCCTCAATTTCATAGCCCCGGGCGGTTCCCAGCATGGCCCCTTCACAG
Seq A exon
GTAAGGAGCCTGAGATATGGAATGATCTGGAGGAGGCAGGAGAGTAGTCTGGGCAGCTTTGGGGAGTGGAGCAGGGATGTGCTACCCCAGGCCCTCTTGCACATGTGGCAGACATTGCTAATCGATCACAGCATTCAGCCTTTCCCACTGAGCCTGTGCTTGGCATCAGAATCCTTCAACACAGAGGCCTGCATGGCTGTAGCAACCCACCCTTTGGCACTGTAGGTGTGGAGAAAGCTCCTTGGACTTGACCTTCATATTCTAGTAGGACATGTGCTGTGTTGTCCACAAATCCTCATGTACCCTAGAAATGAATGTGGGGGCGGCTGGGCTCTCTCCAGAGCTGAAGGAATCACTCTGTACCATACAGCAGCTTTGTCTTGAGTGCAGCTGGGATTTGTGGCTGAGCAGTTACAATTCCTACGTGGCCCAGGCACCAGGAACGCAGGCTGTGTTTGTAGATGGCTGGGCAGCCGCACCGCAGAGCTGCACCATGCTGGTTTGTATCACATGGGTGACCATGGTATGTCTAAGAAGGTGGAGTCCCTGTGAGGTCTGCAGGTGCCCCCACAGCTCCAGGCCACCTTGAGGATTGCCTCTGCCTGCCCAGCCCTGAGTTCCCTCTCCCCTGTCCTGTCCCACTGTCACCCCAAGCCGGCCTCATTGGGAGCCTGTTGGATGGCAGGGTATAGATGTAACCTGATTCTCTCTGGGGAGCGGGGTTATCTGGCTTCTCAAGAGCTCCTAGGAGCCCACAGTGGTGGCACCATCACAGTCGCAGCAGCCCCCAGAGAACGCGGCCCTGTCTGTTCCTGGCGTGCTCTGTGCTGCCCCGCCTGGGTTCCCTGCCCCAGTCGCAGGCCCCTTGGAGGAGGTACCATGTGTCTCCCGTTTCACAGATGAGCCCCGGGGAGCTCACTCTAGTAGTGGCCAGAGAGGCCTGCGGCTCAGGGAGCGGGGCACATTTCCAACAGGACACACCGCCCTGGTCTGAGTCTCGTGGGTAGTGGGAGCAGAGGAGAGCGCCCTATGTCTGTGGGGCGGCTTGGCTGAGCCTGGAAGCCACCTGACCTCCCCCGTCCCTTCCCTGCCAG
Seq C2 exon
GCATCGCATGCGGAAAGTCCATGATGAGCTCCGTGAGCCTGATGGGGGGCCGGGGCGGGGTGCCCCTCTACGACCGGAACCACGTCACAGGGGCCTCGTCCAGCAGCTCGTCCAGCACGAAGGCCACGCTGTACCCGCCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162337:ENST00000294304:20
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.075 A=NA C2=0.354
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATCACCAAGCCGCCCTC
R:
GACGAGCTGCTGGACGAGG
Band lengths:
349-1443
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development