HsaINT0097537 @ hg38
Intron Retention
Gene
ENSG00000119681 | LTBP2
Description
latent transforming growth factor beta binding protein 2 [Source:HGNC Symbol;Acc:HGNC:6715]
Coordinates
chr14:74528483-74529122:-
Coord C1 exon
chr14:74528958-74529122
Coord A exon
chr14:74528699-74528957
Coord C2 exon
chr14:74528483-74528698
Length
259 bp
Sequences
Splice sites
5' ss Seq
CAGGTAACC
5' ss Score
8.66
3' ss Seq
TCTGGCTGTTGGCTTTGCAGAGG
3' ss Score
8.43
Exon sequences
Seq C1 exon
CGGACAAGGCAATCTCCATGCTGCAGGGACTGTGCTACCGGTCGCTGGGGCCCGGCACCTGCACCCTGCCTTTGGCCCAGCGGATCACCAAGCAGATATGCTGCTGCAGCCGCGTGGGCAAAGCATGGGGCAGCGAGTGTGAGAAATGCCCTCTGCCTGGCACAG
Seq A exon
GTAACCTCCTGTTCCCATCCCAGCTTTCACTGCCCAGGGGCTCAAGGCCAGTGACCATGTTGCCAGGCCTGGGTAGACTTCCCTCAATCTGGAAGACTGAAGTAGCCTTCCCTGCCTGCTCACGTGCTTATCCCAACCTGGGGCTCCCTCCCTCCTTGCTGCCACAATTGCCGTGTCTCCCAAAGGGAGGGAAAGGAAGGCCCTGGTTTCCTGCAGGAACAGCACCTCTCAGTTTGTCCTCTGGCTGTTGGCTTTGCAG
Seq C2 exon
AGGCCTTCAGAGAGATCTGCCCTGCCGGCCACGGCTACACCTACGCGAGCTCCGACATCCGCCTGTCCATGAGGAAAGCCGAGGAGGAGGAACTGGCAAGGCCCCCAAGGGAGCAAGGGCAGAGGAGCAGCGGGGCACTGCCCGGGCCAGCAGAGAGGCAGCCCCTCCGGGTCGTCACGGACACCTGGCTTGAGGCCGGGACCATCCCTGACAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119681:ENST00000261978:11
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.671
Domain overlap (PFAM):
C1:
PF0068312=TB=PU(86.0=66.1)
A:
NA
C2:
PF0068312=TB=PD(11.6=6.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGACAAGGCAATCTCCATGCT
R:
CTGCTCCTCTGCCCTTGCTC
Band lengths:
294-553
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development