HsaINT0099004 @ hg19
Intron Retention
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:6846]
Coordinates
chr17:67519655-67521119:+
Coord C1 exon
chr17:67519655-67519782
Coord A exon
chr17:67519783-67521041
Coord C2 exon
chr17:67521042-67521119
Length
1259 bp
Sequences
Splice sites
5' ss Seq
GCCGTAAGT
5' ss Score
10.11
3' ss Seq
GTTGTCTGTCTTCTTTCCAGCCT
3' ss Score
8.33
Exon sequences
Seq C1 exon
ACGTCAAGCCTTCTAATGTACTCATCAATGCTCTCGGTCAAGTGAAGATGTGCGATTTTGGAATCAGTGGCTACTTGGTGGACTCTGTTGCTAAAACAATTGATGCAGGTTGCAAACCATACATGGCC
Seq A exon
GTAAGTACATTAGCTAGGGTGGCATCTGGTAATGTCACTGCCGACAAATCATGCTGGGAAACAAGAAATGGATGGCCACAGAGGGAAAATGGAAATGTACCTAAGACTCCAGAAGTAGTCTGCCTCTTAGTATTTCTTCAAAATTTTATGTCTGAAATCTTTACTCACTTGCTTCGTATATTGTCTTAGTTTGTTCAGGCTGCTATGGCAAAGTAATGTAAGCCAGGCAGCATATAAACAACAGAAATTTATCTCTCACAGTTTTGGAGGCTAGGAAATCCAAGATGAAGGCACCAGAAGATTTGGTGTCCAATGAGGGCTCACGTTTCTCAGGATCATACATAGCACCTTCCTGCTTAGTCCTCGCACGGTGAAAGGGGCGAGGGATCTCTCTAGGGCTTTTTTAATAAGGGCCCCAATCCTATTCATTAGTATTCCACTTTCATGATTCAATCACCCCCCAAAGGCCCTGCCTTCTGATGCCACCACATGTGCGATTAGGTTTTAACCTGTGGATTTTGGTGGGGCACAGACATAGTTATATATATATTACTTTAAAAAAATCAAGTGAAAGAGATACGTTATTTGAAAAAATATATACACAATACATATAGCCTGCACAGTTTTCCACACTGTATTGCAGGGGAGTATTACCTTGTTTGTTGAGGACAAAATAGTAAATAGAGCTTAAATTACCCAAACAAGGCAGTTAGATTAGTTATGAGAGGACCTCACAGCTGTGAAGATTCACCGTCATTAGCAGAGACCTTGCAATCCCCTTTAACTGGAGGAACGGCCACTAGATTCTACCTGGAAATGGACTTGTGCTTTGAATTGAAAAGCTTCCTGTCTGTGTTTAGCTAAAAATTGCTCAGGTCTATTAGCATGGGACAGTAGCCCAGTGACACTTGTTTTATTGAGTTCTGGACTGTTCATGTTTTAAACAAGGATAATTCTAGATGGGCAAAGTAGCTTTATAATGTATACCCTGTTTCTTCTTAAGGCAAATTTTAAATTTGTTATGAAAGGAACTTGATCCATTACTGTGTCCAAGAAAAGACAAACACAGAAGAAGGGAAACCCCACGGAGGCATTGATATTTGTTGTAGTTAACCGGGTCTTCTTGGCCTTGGTGGCATGTTAACAGCTTATAACAACTCACTTGGCAGCTGGTGCTACCCCCATCCCCAGAGACTATTGAGCTAAGAACGTTATCTCAATTGTCTTCCCAGTTTCTCAGTTGTCTGTCTTCTTTCCAG
Seq C2 exon
CCTGAAAGAATAAACCCAGAGCTCAACCAGAAGGGATACAGTGTGAAGTCTGACATTTGGAGTCTGGGCATCACGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984-MAP2K6:NM_002758:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.0=100)
A:
NA
C2:
PF0006920=Pkinase=FE(9.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTCAAGCCTTCTAATGTACTCA
R:
CATCGTGATGCCCAGACTCCA
Band lengths:
206-1465
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)