HsaINT0099004 @ hg38
Intron Retention
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]
Coordinates
chr17:69523514-69524978:+
Coord C1 exon
chr17:69523514-69523641
Coord A exon
chr17:69523642-69524900
Coord C2 exon
chr17:69524901-69524978
Length
1259 bp
Sequences
Splice sites
5' ss Seq
GCCGTAAGT
5' ss Score
10.11
3' ss Seq
GTTGTCTGTCTTCTTTCCAGCCT
3' ss Score
8.33
Exon sequences
Seq C1 exon
ACGTCAAGCCTTCTAATGTACTCATCAATGCTCTCGGTCAAGTGAAGATGTGCGATTTTGGAATCAGTGGCTACTTGGTGGACTCTGTTGCTAAAACAATTGATGCAGGTTGCAAACCATACATGGCC
Seq A exon
GTAAGTACATTAGCTAGGGTGGCATCTGGTAATGTCACTGCCGACAAATCATGCTGGGAAACAAGAAATGGATGGCCACAGAGGGAAAATGGAAATGTACCTAAGACTCCAGAAGTAGTCTGCCTCTTAGTATTTCTTCAAAATTTTATGTCTGAAATCTTTACTCACTTGCTTCGTATATTGTCTTAGTTTGTTCAGGCTGCTATGGCAAAGTAATGTAAGCCAGGCAGCATATAAACAACAGAAATTTATCTCTCACAGTTTTGGAGGCTAGGAAATCCAAGATGAAGGCACCAGAAGATTTGGTGTCCAATGAGGGCTCACGTTTCTCAGGATCATACATAGCACCTTCCTGCTTAGTCCTCGCACGGTGAAAGGGGCGAGGGATCTCTCTAGGGCTTTTTTAATAAGGGCCCCAATCCTATTCATTAGTATTCCACTTTCATGATTCAATCACCCCCCAAAGGCCCTGCCTTCTGATGCCACCACATGTGCGATTAGGTTTTAACCTGTGGATTTTGGTGGGGCACAGACATAGTTATATATATATTACTTTAAAAAAATCAAGTGAAAGAGATACGTTATTTGAAAAAATATATACACAATACATATAGCCTGCACAGTTTTCCACACTGTATTGCAGGGGAGTATTACCTTGTTTGTTGAGGACAAAATAGTAAATAGAGCTTAAATTACCCAAACAAGGCAGTTAGATTAGTTATGAGAGGACCTCACAGCTGTGAAGATTCACCGTCATTAGCAGAGACCTTGCAATCCCCTTTAACTGGAGGAACGGCCACTAGATTCTACCTGGAAATGGACTTGTGCTTTGAATTGAAAAGCTTCCTGTCTGTGTTTAGCTAAAAATTGCTCAGGTCTATTAGCATGGGACAGTAGCCCAGTGACACTTGTTTTATTGAGTTCTGGACTGTTCATGTTTTAAACAAGGATAATTCTAGATGGGCAAAGTAGCTTTATAATGTATACCCTGTTTCTTCTTAAGGCAAATTTTAAATTTGTTATGAAAGGAACTTGATCCATTACTGTGTCCAAGAAAAGACAAACACAGAAGAAGGGAAACCCCACGGAGGCATTGATATTTGTTGTAGTTAACCGGGTCTTCTTGGCCTTGGTGGCATGTTAACAGCTTATAACAACTCACTTGGCAGCTGGTGCTACCCCCATCCCCAGAGACTATTGAGCTAAGAACGTTATCTCAATTGTCTTCCCAGTTTCTCAGTTGTCTGTCTTCTTTCCAG
Seq C2 exon
CCTGAAAGAATAAACCCAGAGCTCAACCAGAAGGGATACAGTGTGAAGTCTGACATTTGGAGTCTGGGCATCACGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984:ENST00000590474:8
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(16.3=100)
A:
NA
C2:
PF0006920=Pkinase=FE(10.5=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGTCAAGCCTTCTAATGTACTCA
R:
CATCGTGATGCCCAGACTCCA
Band lengths:
206-1465
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development