HsaINT0101549 @ hg38
Intron Retention
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:881559-885008:-
Coord C1 exon
chr19:884903-885008
Coord A exon
chr19:881715-884902
Coord C2 exon
chr19:881559-881714
Length
3188 bp
Sequences
Splice sites
5' ss Seq
TGGGTGAGT
5' ss Score
8.73
3' ss Seq
TCCTGCCCCTGATTTTTCAGTTG
3' ss Score
9.36
Exon sequences
Seq C1 exon
GTGCTTTTGTGCGCGTCCAGCCAGACCAGCAGCATCGTGGAGTGCTGGTCCCTGCGCAAGGAGGGACTCCCCGTGAACAACATCTTCCAGCAGATCTCCCCCGTGG
Seq A exon
GTGAGTCTCCCGCCGGCTGCGGAGGCCCTGGGCCTGCCCTCGGGGGCGGTTGGTTTTTATTTTGGAGGCAGGTCTTGCTGTGTCACCCAGGGTGGTCCTGAACCCCGGCCCTAAGCGATCGTCTCGCCTCGATCTCCAGTAGTGCTAGGATCTCGGGTGTGACCGCGCGCCTGCCAGCATTCTGAGTGTGTTAGGCGTATAGACTCCTCCATCCTTCCACGCCCGCTGCGGCGGCTGCCACCATTCTGTGCGAGGCCGAGGCTGAGAGGTGTCGTTGCTCAGCCAGCGGGGACACCGTGAGGGGCTGCAGGCGTGTGGGCGGCTGTGGAGCGTGGGTCTGTGGGTGGGGCCGTCGGGCAGCAGGGGACAGGCCAGACCGGGCAGGGGCGGTGCACGGAATCCTCCGGAACCTGGTTCAGGGAGAGGAAGCCAAGGCTCAGCGGGTCAGCTGAGGCTGCTGAGAACACGCCCCCCACCCCACCCCACCTCTCCAGCAGCCTCTTCTGGGGCCCCCATTCCCATCTCTATCCGCCCGATGGGCCCCCCGCACCCACGGAGCCAAGCCCGTCATCCCCACCTCCGGCACAAAATCCTGGGGCTGGAGCGAAGCAGGGACGCCCGCCTGCTATGACCGGGGACCAGAACAGCCGCTTGGTTTTCAGAGCCTCGGAGGCTGCGGGCCTGGTTTTTAGGCTGGCCTCCGCTCTGGAGAAGGGAGATGTTTTCCCGGTAGATGAGAGCACAGGCATTTGCCGATTAGCGCTAATGGACCCTGGAGTGGCCAGACGTGGGGGCACGTGGGGCAGGTGGGGCAGGCGCTCCTCAGAAGCCACTAATGAGCACGTGTCAAGAGGCCCCGATGGCTCCCGGGGCCTGCAGGTGGTTATGTCAACTGCCCATTGTGGCCGCAGAGGCAGTAAAGGTGAAGAGGGCCACTGCCATTCCTTCCCCCAGGGCTTGTAGTGAGTCACCAGGCAGGTGAAGAGGGCTGCTGCCATTCCTTCTCCCAGGGCTCGTTCCTTCGCCCGGTCCCCAGGGCCTTGTTGGGCCTCATTCCTTCCCCTGGGCCTCGTGGTGAGTCACCAGGCAGTTTGGGCTGCGCTGGCTCCTGCAGCAGCACCTGGCGCCACCCCGTGTGGCTGCACAGACCTGCACCTTCACTGCCCGGTGCCCCCGCTGGGCACGTCTGTGTCTACCATCTGCCCACAGCCAAGCCACTGGGCAGTCCTGGGCTCCGACACTCCTCCTCGTCTCCTGCAGCCGTCCTCACCTGCTGGCCCAGCTGTTACCCGCCCGAGAGCCACGTCTCACACACATGCCACAGCCTTTCTCAGGTCTCACATCCCTGGCAGCTGGGGGTCACTGGGACAGTCCCCACCGCACCCATCTCTCCCCCATCTCTCCCCCTACCGCCCCACGTGCCCACCATGCCAGGCTTTGGTCCCCGCCATGCCCAGCTCTTCACGCACCGCCCCACGTGCCCACCGTGCCAGGCTTCGGTCCCCGCCATGCCCAGCTCTTCACCCACCACCCCACGTGCCCACCGTGCCAGGCTTCGGTCCCCGCCATGCCCAGCTCTTCACCCACCGCCCCACGTGCCCACCATGCCAGGCTTCGGTCCCCGCCATGCCCAGCTCTTCACGCACCGCCCCACGTGCCCACCATGCCAGGCTTCGGTTCCTACCATGCCCAGCTCTTCACCCACTGCCCCACATCCCCACTTAGCAGCTTAGCTTCTCCCTGCCTCAAGTCCCCCCTCATTTAGGAATGCTGACCGCAGCCGTCAGTTGGATGGAGGAGGGGATGTAAATCGTGCTGTGAGGGTACCCTGGCCACTAGCTGGGGGTGTGGTCGTCATGGCAGCTGCCTCCCCCGGCGCTGGGGCGTTGAGTTTCCTGTCTTTCCTATGAGAGGCTCAATTCCATGAGGGCCAGCCACCCCTGACCACTGTGTGCCCTCTGGGCGTCTCAGCCACTCTCTGGGCCTGTTTCCCCCCAGGGAATGCTGCTCACAGGACCCCTATACGGGTTTGCAGGAGGTCAAGGCTCTGTGACCGTGATGGCCCGTCCGGGGCAGAGACCTCATGATGCGGGTGGCACAGAGCAGCTGCGTGGTAGTCAGCTTCAGCCGAGTAACAAGCCAGCCCCAAACTGAGCAGCTCAGGCCAGCAGCCCTGCACTGTTTCTGTTTCTGTGGCTGCCTCAGCTGCGCTCTCCTGGTTCCCACGTGTCTGCGGTTAGCAGCCGAGGTGGCGTGGCCTGTCCACTGGCCGCACATGCTCCAGCAGGCCGGCTCCAGCTGCCCTCCGTGTCCCACATGCAGCCACAGCAGGACCCCCCACACGTGCTCTCTGGGCCACTGTTTTTGTTTTTTGTTTTTGAGCTAGGCTCTTGCTGTGTTGCCCAGGCTGGAGTGCAGTGGCGTGATCTTGGCTCACTGCAGCCTCATCTTCCTGGGCTCGAGCAATCCTACCTCAGCCTCCTGAGTAGCTGGGACTACAGGCGTGTGCAGGCGTGCATCACCACCACACACAGCTAATGTTTACTGTGTTTTTTTTGTAGAGAATGGGGTCTTGCTGTGTTGTCCAGGCTGGTCTTGAACTCCTGGACTCAAGCCATCCTCTGGCGTTGGCTTCCCAAAGTCTTGGGGTGGCAGATGTGAGCTGCTGTGCCCGGCCATGTCACATTTGCTAAGGCTTGGCCTGAGATTCCCAGAAGTCTCTGCCCTGTTGGGAGGAGCTGCGTCTTCACGCAGGGGCTGTCAGGCAGCGGATCTGTGGGTGCGACCATCCCGCATGGCTTTATTGGAATTGTAGATGAGGAGGGATGGGAATCCCGGCTGAGCTGGCTAAGGCCGAGCGAGTGTTAGGGTTTGCATGGCTGCAGGTCTGAGGTGGCGCCGTCTCCCCACTGTCTGCCCCATCGGGGGTGAGATGGTGCCGGCCCACAGGTTTCCATGAAATCCCAGGGCCCACCTTGGGTCACGTGCCCATCCTGGAACCAATGAGTGGCCGAGGCACGAAGCGCTCGGATTGGCCGGGCCTGGTCTTCTGGGCATGGGAGCAGGGCGGCATGAGACCTGGGAAGGGCCCTGGGCAGGTTGCACACCAGGCCATGCTGGACTCCTGCGGCTGTCTCAGCCTGTCTTTACTCCATTGCCTTCCTGTTTTCCTGCCCCTGATTTTTCAG
Seq C2 exon
TTGGCGACAAACAGCCCACAATTCTCAAATGGCGGATCCTATCGGCCACCAACGATCTGGACCGTGTGTCGGCCGTGGCGCTGCCCAAGCTGCCCATCTCGCTCACCAACACCGACCTCAAGGTGGCCAGCGACACACAGTTCTACCCTGGCCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221:ENST00000395808:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.007
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(16.5=100)
A:
NA
C2:
PF116353=Med16=FE(12.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development