HsaINT0101805 @ hg19
Intron Retention
Gene
ENSG00000157890 | MEGF11
Description
multiple EGF-like-domains 11 [Source:HGNC Symbol;Acc:29635]
Coordinates
chr15:66187634-66191272:-
Coord C1 exon
chr15:66191066-66191272
Coord A exon
chr15:66190433-66191065
Coord C2 exon
chr15:66187634-66190432
Length
633 bp
Sequences
Splice sites
5' ss Seq
TTGGTAGGT
5' ss Score
7.03
3' ss Seq
TTTTTCACTATATTTCTTAGAGC
3' ss Score
7.57
Exon sequences
Seq C1 exon
ATTACATGAAAGAATCCGTGTGCAGTTCTAGTACTTGTTCCTTGAATAGCAGTGAAAACCCTTACGCCACAATTAAGGACCCACCCATCCTCACCTGCAAGCTTCCAGAAAGCAGCTATGTAGAAATGAAGTCGCCTGTGCACATGGGGTCTCCGTACACAGATGTGCCATCCTTGTCGACATCTAATAAAAATATATATGAAGTTG
Seq A exon
GTAGGTGTCTCAAATAAGTAACTTAGTGAAATCAGGGCAATAGTGCAGCATTTGAAGTAAAAGCAAGCCCTCTCCACTCACCCCACCTTGACCACACATCCTTCTTTTGTTGCTTTTAAAGGCATCTCTAAGGTGAACTGTCTTTCCTAGGACTACCCTCCTAGCTAATGCAGGAAGTCAAATTATTGTACCAACTCTGCTTTAAAAAACACCAGGACTAATATGAAACAAATACTGGGGGTGGGAAATGGGCACATGCACGTGCACGCGCGCACACACACACACAGATTGTTGATACAAATCTCATTTTAAAAAAGAAAGCAATCAGAGACATCAACAAGTCTCTAAATCACCTTCTACCTTCTCCCAGTTTATGTCCCTGGGCTCACTGGTAAGACTCCTACCTCTAGGATATTTTAAATCCTTTGGTGTTGATGAGAGGCTTGGATGTTGACAGCACATTCACTTAGTTTTCCATCTCCTGAGCAAGCCTCAGTCCTAACCCTCATGTATTTGCCATAGATTTATAAATCCCTGGCTCCTTTCCCCAAGTTAAGTAGAACTCTCTTCCTCTCCAACAAGGCAACCAAAGCTAATCTGTTCTCTGAACTCATTTTTCACTATATTTCTTAG
Seq C2 exon
AGCCCACAGTCAGTGTGGTCCAAGAAGGTTGCGGTCATAACTCCAGCTATATCCAGAATGCATACGACCTACCTAGGAACAGCCATATTCCTGGTCATTATGACCTCCTCCCAGTAAGACAGAGCCCTGCCAATGGGCCGTCCCAGGACAAGCAATCTTAAGAGGGATAAGCTTCTCTCTTGCAGTGTGCTCTACTGAATATTCTGACTCTGAAAGAAGACAGTCCCTTGACTTGAAGTAATGGTACAGACTGGCTCCAGCTGCATGTTAGTTATTACGTTCACCTGGAACTAAAGAAGAGCGTCCAGGTGGGACTGGGATAATTGTTCAAGGAATTGTGTTCTCAAAGGCAAATCCTATCACCCACTCAGCCCCAAATGCCCTGGATTATATGATTTTTAAAACATTTTAAGATACAGCTACTCATCAACATCAGCTAAATATAGCTGATATATATATATATATTTATCTGAAACGTGATATTTTAAAAACATGTAGGTTTAACAAACCTTCCTAGGACAAAAAGGAGACTGGGGAGGGAAGAGGATTACTTTAAAGCACCTGAAACGTATATGTACTTTTGGTTGCTGTTACCATCAACATCTGTTTTATTACCGAAGACAATTAGTACACAGACATGAACTGTTCTTAAACAGAACAGTCTTAAAATGTCTGTACATATCTGTCTGGTCCATCAAATTACAACAGCCAAGATTACAGAATCTATATAGTCTAATGCTGACAACTTCTATTTTAAAAAACAAGACTTTACTTTCTTCTGCCCCCTAAGTGATAGGTTTAAACACACAGAGACACACACACACGTTTCCAAAGTGCAGCAGTGTCTCTTTCAGTCTACAATAAGATTCCTAGGGCAGCTTTATCAAATTTTGCCAATTCAAAGTTCAAGGACATTACAAGTTAGTCCTGGCTTTGTCATATCTACTTAGTCCATCCGACACCTGAATCATTCCATGTAAAACAGAGCTCTAAGATGATCCTTTAAGCAAGCAGTCATAGACTGGTCGGGATTAAGTAAAAGACGGCTAGTTGGCCTCCTCATTTTATTTGGTCAGCATCCCTTGACTCAAGAGTACTTGCTTTCAAGTTCTTCATAAATCTTGAGATTGACGTAGTATGAAACCTAAAAGTATACAGGAAATTGGACAAATGTGGATACAGCAAGTTTACACTGCTTAAAGTACATTATGCTTTTTAATGGAACTAAATGATCAAAAAAAGAATGGACTGTAACCAGTTGCTGTAACGTGATGTAAAAACGTTACTGTAAACAGCATGAGGATATGAAGTCCTTCCACCTTCTATCTTAAAACTACTACTTACTGAGCTAGCCCAATATGCATTACAATGAGCTAATGCTCCAGATCCCAGTATTCAGATGTGTCTATACCTTCCACTATGAACACAGATAAACTGAGGCTCAGATAAGTCCAAATGAAATGAAATCAACTCCCAAGCCCTAAAGAGAACCTTCTCACAAGAATTAAAAACAAAAAGGGCAAACCTAGGAAGCTAACGGCTACTCCTGTACCACTCTATTCACTGGTACAGTCCAGCCAGTAAAAAACACTTCCAAAAAGATACACAGAAGAGGAACTAAATGACTGCGAAGCTGGAATACTGCTACAGGAAGTATGAGAGTTCTGAAACCCTTGATAGAAACTGGAAGCCTGCCATGGAACACAATACTTTGGGCAATAATCAGAAAAAGCAAAAAAATAAATAAATGAGTACATCTCCCCTTCCCACATCACTCAAGGCATAAGCAGATTTTACTGTTAGAGGAAAATATGTAATACTTACATGAATGTTGCATGTGTGCATGGGAGCAACTGAGTAGCAATAGTAAATTTACTTTCCAAAAAAGCCTTATTAAAATATAAATATTAGAAAATTACTTTGGAGACCCAAGTAAATATTTCTCATACATATGTAGAAAGAAATATAGGTAAGCAGCTTACCTCAGTATTTCAGGGCAGCAAGTGTTTGTGAAGCAAGGATGAGCAGCATGAAGATGTCAGATCAGCAAGGAGAAACTTCAACTCAATCCCAGGTTTTCTCTTCTTCCCTTATCCTGCATGTACAATAACTGCTGCCTGGCAAACTGCAAACAAGCAGCATCACTCAAGTTTGAAGTTTCGCCGCTTTTGTCAACTATCCTCTGGGCAAAGGTATTCAGCAAGAGGTGGAATGGCTAGACACTGAATCAAGAGATTTCAGTGTTACTCTGGTCAAGTTAGTCGCCCTCTCTGGGCTCCCTTTTTTCCTATGCATAAAAAGGGGAGAAGCAGAGAGTGGGAAGACAGCTCTACTAACCCTTCAGCTCTAGCAGTCCATGACTTTTTAAGGAAATGTAATACAAGTCAAACCAGGCAATACAGAGGAGAAGGGAAAGGCAGAGGGTGTGATTATGGTGACAATAGCTGCCTTCCCCTATCGAACAGTTATCAGTAAAAGACATTTCAATCTTACAAAGCAACTGTTAGAAACTTCTGTCTAACACCATCACAAATAGGTTCATGGTCAGCCTAAACATGTATACTGTGCATTTTATGGGTGACTTTGAAAGATCTGTTCAATTATTTTTCAGAAACTAAATTTTCAAAAAATTAATATGTGTACAATTAAAATGAATGAAAGAAAAACCATTATTGTACAGAGGTATTAATGAGACTATGAAACGGCAATACTTTTTTAAATCACAGATTTGTAATATATGTTCACTGTGCAGAGGGATTGTACCTTGTACAAAATAAAACAAATTTCTCAAACTAATTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157890-MEGF11:NM_032445:22
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.301 A=NA C2=0.472
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAATGAAGTCGCCTGTGCACA
R:
AACTAACATGCAGCTGGAGCC
Band lengths:
357-990
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)