HsaINT0101819 @ hg19
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF-like-domains 6 [Source:HGNC Symbol;Acc:3232]
Coordinates
chr1:3421986-3422800:-
Coord C1 exon
chr1:3422672-3422800
Coord A exon
chr1:3422121-3422671
Coord C2 exon
chr1:3421986-3422120
Length
551 bp
Sequences
Splice sites
5' ss Seq
TCAGTGAGT
5' ss Score
7.68
3' ss Seq
CAACGGTTCTGTGGGTGCAGCCT
3' ss Score
3.85
Exon sequences
Seq C1 exon
GCTGCCCCAAGGGCTACTATGGCAAGCACTGTCGCAAGAAATGCAACTGTGCCAACCGGGGCCGGTGCCACCGCCTCTACGGGGCCTGCCTCTGCGACCCAGGGCTCTACGGCCGCTTCTGCCACCTCA
Seq A exon
GTGAGTCTCACTGCCCCTTCCAGTGTCCATGGTGGTGGCAGCGGGTGGAAGGGATGGTCCATGTCCTGTTACCTGTAGTCTGGGTTAGGATGAGGCTATCGGGGCCCAGCCAGGTCACCCACTGGGATGTAGGTCTGGGGTCCGCCATGAGTCTGTGGACTCCAAGCCACATCCTCTCGACTGTGACTGTGCTGGCATCCAGGGCGTCTGGGTGGATGGTCCCCAACCTTGTGCCTCCCAGCCTTGATGGGTGGTAGGGCTGCAGATGAGGGCAGGGCCAGGCCTTTTGCAGAAGCCTCCGGGGGATGAGGCCTATCTTGGCTTTTGGAGATTCCTGGCAGCAAGGCCAAGCTCTGAGTCCCTGGTGGGGTCACCCATCCCTGGGGTTCAGACACTCAGGGAAGGGGCGGTGGGCTGCAGGGGGAGAGGTGGAGGAGGACAGCTCCCTACATGATCTTGGCTGTCGTCCTGGCTGACCCAGGGCTGGTGGAAGCGGTCTGGGAGGGTGGGGCTTCAGACGGGAGCCCCCCTCAACGGTTCTGTGGGTGCAG
Seq C2 exon
CCTGCCCGCCGTGGGCCTTTGGGCCGGGCTGCTCGGAGGAGTGCCAGTGTGTGCAGCCCCACACGCAGTCCTGTGACAAGAGGGATGGCAGCTGCTCCTGCAAGGCTGGCTTCCGGGGCGAGCGCTGTCAGGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591-MEGF6:NM_001409:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PD(34.0=36.4)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCCAAGGGCTACTATGGCAA
R:
GAAGCCAGCCTTGCAGGAG
Band lengths:
238-789
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)