HsaINT0101832 @ hg38
Intron Retention
Gene
ENSG00000162591 | MEGF6
Description
multiple EGF like domains 6 [Source:HGNC Symbol;Acc:HGNC:3232]
Coordinates
chr1:3496655-3497361:-
Coord C1 exon
chr1:3497233-3497361
Coord A exon
chr1:3496784-3497232
Coord C2 exon
chr1:3496655-3496783
Length
449 bp
Sequences
Splice sites
5' ss Seq
AGGGTAGGT
5' ss Score
8.1
3' ss Seq
GCTAGCCCCTCTCCCTGCAGGAT
3' ss Score
10.59
Exon sequences
Seq C1 exon
CCTGCCTGCGGGGCTGGTTTGGAGAGGCCTGTGCCCAGCGCTGCAGCTGCCCGCCTGGCGCTGCCTGCCACCACGTCACTGGGGCCTGCCGCTGTCCCCCTGGCTTCACTGGCTCCGGCTGCGAGCAGG
Seq A exon
GTAGGTGCTCCCAAGCCCCCACCCCGAGGAGCGGCTGGGCAGGGGGAATCCAGAGAGGCTGCCTGTTCCTTGGCGGGGCTGGGCCAGGACCGACCCTGCCTGTCTCCACCCAGCCTGCCCACCCGGCAGCTTTGGGGAGGACTGTGCGCAGATGTGCCAGTGTCCCGGTGAGAACCCGGCCTGCCACCCTGCCACCGGGACCTGCTCATGTGCTGCTGGCTACCACGGCCCCAGCTGCCAGCAACGTGAGTGCTGCCCGTGCCCACCCAGGGACTCGGCAGTGCTGCCTGGCGTGCTGGGCCCCAGTTCCCCTGGTCCCCGGGAAGGCCCTCATCTGAGGGGGTGGAAGATGGAGGGTGTGGGGGTCTCATGAGAGCTGCCTTGCTGTGTTCAGGGGCACTGGGGAAGCCTCCAGCCCCAGCCCCTGCAGCTAGCCCCTCTCCCTGCAG
Seq C2 exon
GATGTCCGCCCGGGCGGTATGGGCCAGGCTGTGAACAGCTGTGTGGGTGTCTCAACGGGGGCTCCTGTGATGCGGCCACGGGGGCCTGCCGCTGCCCCACTGGGTTCCTCGGGACGGACTGCAACCTCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162591:ENST00000294599:22
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.051 A=NA C2=0.236
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(67.4=65.9)
A:
NA
C2:
PF0005319=Laminin_EGF=PD(34.0=36.4)
Main Inclusion Isoform:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTGGTTTGGAGAGGCCTG
R:
TGAGGTTGCAGTCCGTCCC
Band lengths:
246-695
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development