HsaINT0102191 @ hg19
Intron Retention
Gene
ENSG00000087995 | METTL2A
Description
methyltransferase like 2A [Source:HGNC Symbol;Acc:25755]
Coordinates
chr17:60501580-60504015:+
Coord C1 exon
chr17:60501580-60501671
Coord A exon
chr17:60501672-60503659
Coord C2 exon
chr17:60503660-60504015
Length
1988 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCGC
5' ss Score
9.05
3' ss Seq
TTTTTCTTAAATATTTACAGTTG
3' ss Score
7.43
Exon sequences
Seq C1 exon
GGACAATGTGGAGTGGTCGGAAGAGCAAGCCGCGGCGGCGGAGAGAAAAGTCCAGGAGAACAGTATCCAGCGGGTGTGCCAGGAGAAACAAG
Seq A exon
GTGCGCTTAAATGGGCTCTCATTGGTATCAACAGCCAGCGTACTGCCGAACGCGCCCTCCCGGAGAGGCCAGGGAACCGCGGCCGCCCAGATCCTTTATTCCTGGCCTGATGCAGATCTCAGGAGTAGAGCGGGACAGGGAGGGGATGAGCAAGGAGAGAAAAGGGCTGCATTGTAACAAAATCTTAAGTCGTAGAGGGTTTTTTTATATATAGTTTTACTTTGGAGGAGGGTAATGTTGTCTTTAATTATGTTTAGTAGATCCACGTTGATATGGCTAGCCAATGACAACTGTGTGGTCACGCGATCATCTTAGAACCTGTACTTTTTACTTGATTTGCATTTTCCATGAGGAGATGTTTTCCATTGAAGCTTCATTGAAGTGATTAGATTCTAAATATTGTTGGGAGGGGGGCTAGTGACTGGTGACTGTGTGTCTATTACTTGTGTGATGGTTATGAGAATTTAGGGCTTTAGTCAAGGAAAGGTGGATGCAGCAGAGTGGAGATAAGTCTGGCCAAAGAAAAGGAGGCCCCTGCTTGAGAGGTGGATGATTTCACTGCAAAATATCCCTAGATAGTAAAACTAGGACTGATTGTTCCAGACAATTGAAGATAGGACTACAAATTTAGTACCCGCTGAAAGAGTTCTGTACAACAAAAAGATTCCAGTTACAAAACATTCACCCTGCATATTTTGACAGCAACTAGATCAAAGCAAGTTAATAGTTGAAAGGGATTTTGAAAATCATGTGGTTCAATATTCTCTTTTTATAGTTAAAGACACTTGGACCACAGGACATTAAGTGCTTTTCCCAGAGGTAAGCAGTCAGTAGTAGCAGTAGTGGAACTAAAATCCTGTTTCTTAGGGAGTCTTGGTTGATTCAGCAGGTGAGTTGTGAGTTGTTAACACACTTCTTAGTGGATTCCAACTTCCATTGTCACTGTCCTGCTCAATTTGTTAGGTTTTTATTCTTTCTACTACACTAGTCAAGGCCCCCTGAATTGGCAAGAGCAGTAAACTGAAATCTGGGACTGTCATGATCACCTTAAAAACAGCCTTCATTTAAACTGTCCATACTTTTTTTTTTTTTTTGGAGATGGAGTCTCGCTCTGTCACCAGGCTGGAGTGCAGTGGCACGATCTCAGCTCGCTGCAATCTCCTCCTCCCTGGTTCAAGCGATTCCCCTGCCTCAGCCTCCCTAGTAGCTGGGACTACAGGTGTGCACCACCACGCCTGGCTAATTTTTTGTATTTTAGTACAGACGGGGTTTCACCGTGCTGGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCGCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACTGCACCTGGCTACTTCTAGGATTTTTTAATAGTTAAAAGTCATCTGGCTGGGCGCGATGACTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAGGTCAGGAGATCGAGACCATCCTGGCTAACACGGTGAAACCCCGTCTGTACTAAAAAATACAAAAAATTAGCCGGGCGTGGTGGCAGGCGCCTGTAGTCCCAGCTACTCAGTAGGATGAGGCAGGAGAATGGCATGAACCCGGGAGGTGGAGCTTGCAGTGAGCCAAGATTGCGCCCCTGCACTCCAGCCTGGGTGACAGAGCGAGACTCTGTCTCAAAAAAAAAAAAAAAGGCATCCAAAGATGTAGGAGGACACTTGATAGATAGTAAGTTCTCTGGTTGATTGTTCAAACAGAATTTAGACTCTCCTATAATGACGGATAGGGGCATTAGGGTATAATGCCAGATGGCAGGACTAAATGACCTCAGAAATGCCTTCAGTTCTGGGACTGTGGCTCTACCTGAGGATACTTTTAGTATTAAAGTGACATTTGGTAAAGCAGGATAATTGATATTAGATATAAATAAAACATTTGAGAGCTGGTTCTTAAAATTTTTTCTTAAATATTTACAG
Seq C2 exon
TTGATTATGAGATCAATGCCCACAAATACTGGAATGACTTCTACAAAATCCACGAAAATGGGTTTTTCAAGGATAGACATTGGCTTTTTACCGAATTCCCTGAGCTGGCACCTAGCCAAAATCAAAATCATTTGAAGGACTGGTTCTTGGAGAACAAGAGTGAAGTACCTGAATGTAGAAACAATGAGGATGGACCTGGTTTAATAATGGAAGAACAGCACAAGTGTTCTTCAAAGAGCCTTGAACATAAAACACAGACACTTCCTGTGGAGGAGAATGTAACTCAGAAAATTAGTGACCTGGAAATTTGTGCTGATGAGTTTCCTGGATCCTCAGCCACCTACCGAATACTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087995-METTL2A:NM_181725:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.344 A=NA C2=0.085
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF134891=Methyltransf_23=PU(17.6=28.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGTGTGCCAGGAGAAACAAG
R:
GCTGAGGATCCAGGAAACTCA
Band lengths:
358-2346
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)