HsaINT0102235 @ hg19
Intron Retention
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:25856]
Coordinates
chr2:172188314-172194012:-
Coord C1 exon
chr2:172193963-172194012
Coord A exon
chr2:172188378-172193962
Coord C2 exon
chr2:172188314-172188377
Length
5585 bp
Sequences
Splice sites
5' ss Seq
GGAGTGAGT
5' ss Score
6.05
3' ss Seq
TATTTCTTCCATCTTCATAGGAA
3' ss Score
9.3
Exon sequences
Seq C1 exon
GTTGGTTGTGGAGCTGGAAATAGTGTGTTTCCAATTTTGAACACTTTGGA
Seq A exon
GTGAGTTTTAAGAGTTTTCTTTCTACAGAATTTTACATATTTATGGAATGTTGAGAAATTCTGGGAAAATATTGTCACGTGTATGCCAGTAGTGTTTCTAATTCTTATATGAACAATGGCTCAAGCAAATTTCAAAAGAAATGTCTTAATCTCAATGTCTACTTTCATGTGAACTGGGAATTACTCTGAAAATAGTGTTTCGTAGCCATGGGTTGTCCATCATTGTTTTGAAGTAATTTTTTAAGCTTATGTGTATATGGATGAGAGAATAAGAAAAGAGGAAGCAGACTGGGCATGGTGGCTCATGCCTTTAATCACAGCACTTTGGGTGGCTGAGGCGGGTGGATCGCTTGAGGTCAGGAGTTCAAGACCAGCCTGACCAACATGGTGAAACACCACCTCTACTAAAAATACAAAATTAGCCAGGCATGGTGGCGCATGCCTGTAATCCCAGCTACTTGGGAAGCTGAGGCAGGAGAATCTGCTTGAACCAGGAGGCAGAGTTTGCAGTGACCCGACTGCGCCATTGCACTCCAGTCTAGGCAACAAGTGCAAAACTCAGTCTCAAAAAAAAAAAAAAAAAAAAAAAGAGGAAGTGATTTCATCCTTCCACTGAGCTGTGAACTGCTAAACTTCAGAGATTATTTACTCTCCCTAGATACTTAGATGTCATTTTACACATAGACAATTGAATGTAAAGCTTACAACTTAAGCCTCATTTTGTCATCCCTTCTGAAGCAACACCCTATGTAAGATGTTTGCATGCCAAATCATTGTGTCTAGGCTTAAAATTGTTTGGAGGTAGCAGCAACTAATCCTAAGACTCAAAAAAGCCGATCCTGGCTAACACGGTGAAACCTCGTCTCTACTAAAAATACAAAAAATTAGCCAGGCGTGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAGGCCGAGCTTGCAGTGAGCCGAGATCTCGCTACTGCATTCCAGCCTGGGCGACAGAGTGAGACTCCGTCTAAAAAAAAAAAAAAAAAAAAAAAAGCAGTCGGGCGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGCGGGCAAATCACGAGATCAGGAGTTCGAGACCAGCCTGGCCAACATAGTGAAACCCCATCTCTACTAAAAATACAAAAAATTAGCTGGGTGTGGTGGCGGGCGCCTGTAATCCCAGCTACTCGGGAGGCCGAGACAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATGCGCCACTGCACTCCAGCCCAGGCAACAGTGCGAAACTTTGTCTCAAAAAAAAAAAAAGCAGAGTTTGACTACAGGGACAGAGATTTGCTCCAGGCTCACCCTTCCTGTTCACCATTTCACCTGTGTCTTTTACTTTTTCCATGATGAACACACAAAACTCTTCAAACACCTTTTATCTATGGCCAATCTGCCAAGCTCTATTCTTTTTTAAGTTTACACATTTTTTTTAAGTTCACATTATTTTTCCATTATAAAATCAGCATTAGCACGTTGCAGAACATTTCCATTAGAGGAAAAGGAGAGGGAGGGAATCACTCATCATCCTAACATAGCCACTGACAAAATTTTTGTTTTAATTCCTTTCAGTCTTTATGCATATTTTTAAATGATGTGATCTTTTAAACTTTTTATTATTAAAATGTAAAAGCATCTGGGGCCTGGTGCGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGACGAGGCAGGCAGATCACTTGAGGTCAGGAGTTTGAGACCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGAGTGTGGTGGTGCACAATTGTAATCCTAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGTGGAGGTTGCAGTGAGCTGAGATCGCACTACTGCACTCCAGCCTGGGTGACAGAGCAAGAGACTCTGTCTCAAAAAAAATTTTTTTAATTAAAAAACATTCAGAAAAGCAAAGAGTACAGTGAATTTCCATATGCCTAACACCTCAATTCAACAATTACCAATATAATGCCAACATCATGATACTTTATCCTTGATTATTCAGGATATATCTCCCAAAACTCAGTATACTCTCTAATATTATTATAAACCTAACATAATGAATAGTGAGTAGTTTCCTACTATCATTTAATAACCAGTTAATGTGGCCAGGCCTGGGTGATGCTGGTAAATTTACAGTTCTGAATGTCCTTTCTGTTTGTGTCTTTGTTAGTTTTGTTTTCCTTTTTCTAGTTTCTGGGCTGAAATTTCAAACTTGCTTATGTCACATAGCCATATTCCTTTACCCCAGTGGTCTCTGAGCTTATAATACACGTAAATACACTACATTGGCAGTTGATTGTGTGTTACTTTATGACTGATCTCAAGGTATTATTTAGCATGTCATTTATTTATGCCTTGTCTCTCCGACCACTTTTTATATTCCTTAAGGTAGAGGGCATATTTTATCCTAATCTGATTTCCCAGGTTGCCTAACAGTACAGCTTAGTTGGAGCTCAATACATATTGCCTGATTAATATCTCTCATTCCCCCACTTGCTAGTTGTATTTTTCACCTCTGCTTCTCCCTTCAGCTTATAATTGCAAGCTCTTGGTTCCTCACTCCCTAACTCTTTCTTCTTAGCTCTGTCTTTCTTTGCCTCATACCTATGTTTTAGAAATTACTGTAGCTCAATAACCTCAGATAATTAATTCATCTTTTAAAGGCAACCAGTGATTAGCCTTCCAAAGGAATTATTAGACTTTTTTTTTCTGCTTAAGAAATTATGTTTTACTACTTTTAGAGAGTGTAGGATTAATGTTTTACATTTTCAGAATATTTTACCATAATTAGACCTCTGAAATGGAGAGGTCATATCATTCTCCAAGGATCATTTAATTCATAGACCCCTGCCAAGAGAGTGCTTGGTGGTGTGGTGGTAGTAGTGATATTTACACCTGTTTGCTGGGAGAAGAGCCAAGGTAGTCAGCTGATTTTACAGAAAGGTTCTGGAAAGTCACTGGGTGGTCACAAGACATCACCTTGGGCTGCTGATACAGTGGGAATTCCATCTTAGAGGTCATGCTGCCACCGTGGCAGGACACATGGCATATGGCACATGCTTTCCTTTAGCTCGTAGACTGTTCTATATCTTATGGGTATGTGGTAACTACTGCCCAAAGGTAGACTGCAGACCTTTTATAATGAGCTAGACATACCAGTGTCCAGAAAAGCATTTTGAACTATATGGAAGTTTTTTGGTTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTGTTTTAGAGGACTATGTTAGTTTTTAAGCTCCTGGAAGGCAAAAACAATCTCCTTTAATAATAATAGTGATGATAATAATAGCAACAACAATTATAATAATGACTAACATTTATTGAGTGCTTACTCTGAATCAGGCACCTTTCTGGAAACTTTAGCTATAAGAATCCATTCACTTCAAACAACCATCTTAGATGCCATGTTTATCTCTTTTTTTAAAGATGAGGGAATTGAATTAAAGAAGAGATTAAGCAACTAGCCCAAGGTCATGCAACTATGTAGTAAAGCTGAGACTCAAACCTTAGGCAGTCTTGTTCCAAAGCCCCTGCCCTTAACCATTAGCCACATAGTGCTGAGTGTTTACTGAGAACATTTCAAATACATTTCAAACACCCAGCAAATTACAAGTCACAATTATATGGATTTAATCAGAAAAAAACAGGGGAACATGCTGAAGTAAAGTGCTATTTTTATGTTTGACAGATGAGAAAAGACCAAGCAGTATGAGTTTTAACTTTGATTCAGTACTGGTTAGCTTTTCATAACAAAATCCTATTAATCATACTTTAACTTATTTGGATAGATCTTAAATTGAATGCAAATCCCTAGTGCCATAGAATGAGTGAATTATATGTTATCATAGTTATTCATCAATGAGTTGCCTTTAAGAATATAATCTGAGGCCAGGTGCGGTGGCTCACTCCTGTAATCCCAGCACTTTGGGAGTCCAAGGTGGGTGGATCACCTGAGGTCAGGAGTTCAAGACCAGCCTTACCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAATTAGCCGGCCGTGGTAGCACATGCCTGTAATCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAACCCAGGAGGCGGAGACTGCAGTGAGCCGAGATTGCACCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGGGGTCTCAAAAAAAAAAAAGAAAAGAAAAAAAAAGAGTATAACCTGCACCTGGGTCAGATTTTGCTAAATGCATATTTATTTAGCTAAATAAATTCCATATTTATTTAGAGGTTCACCTTGCTTGGAATGCTTCTTGAGTCAGATTAGAAGTCTTAATGATATGCTTCAAGGCCCACCTTTTTATCCTGCCATATACCAGTTTGGGCTCTCAGGATTAGTGCTACTTCTCATCCCTGGCATGTGACTCCCACTTCTAAACTCTTCAACCATTTCCCCTTCTCCTCACTTAACAATACATCCTCCTCCTTCAGAAATTTTAAGACTTATACCTCAGGGTGCTGACCCTCTTGACACCCCTGTAGAAGTTGTATAAAACCAATTATGTCCCCAACTAGACTATAAAACCCATGAGAGCCAGGACCATCCTTACTGTTTAATGACATGCTGACCTCTTTCTGTAGTTCAGACATGGTACTAAGCAACATGATGCAAGGATTATTTGATACCAGCATACACAGTATAATCAAGAGGAGTATTAGTCTACAAATTTCAGAGTATATGGCTGCCTTAAGTAACCATGGTCCAGCCATCATTACTGAATTTCAGATAAAGGCCAAACAGAACATATTTAAGTTAAGAAGAGTCCAATTAAAAATCATACCACCTATTGGCCAGGCACAGTGGCATACATCTGTATGTAGTTCCAGCTACTCGGGAGATTGAGGCGGGAGAATCACTTGAGCCCCAGAGGTCGAGGCTGTAGTGACCCGTGATTGTGCCACTATACTCCAGCCTGGGTGACAGAGCGAGACCCTGTCTCAAAAAAAAAGCTGAGGGGCGGGGGTGGAAATAACTTATTAACAAGTCAGACCTACAGTTTCCTTTCTTCTCTAGTTTGAGTATTTCTAGACTCCAGATATAAATATTTCTTCTGGCCGAGCACAGTGGCTCACACCTATAATCCTGACAGTTTGAGAGGCTGAGGCAGGAGGATCATTTGAGAACAATAGTTCAAGACCAGCCTGGGCAACATAGTGAGACCCCATCTCTACAAAAAAATCTAAAATTAGCTGGGCATGGTGAGGCACATCTGTAGTCCTAGCTACTCAGAAGGCTGAGGAAGCAAGATCGCTAGAGTCCAGGAGCTCAAGGTTATAGTGAGCTATGGTCACGTTACTACACTCCAACCTGGGCAACAGCGCAAGACCCTGTCTCCAAAAAAATAAATAAATATTTCTTCCATCTTCATAG
Seq C2 exon
GAACTCTCCGGAGTCCTTTCTGTATTGTTGTGATTTTGCTTCTGGAGCTGTGGAGCTCGTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600-METTL8:NM_024770:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF082427=Methyltransf_12=FE(15.2=100)
A:
NA
C2:
PF082427=Methyltransf_12=FE(20.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)