HsaINT0104177 @ hg38
Intron Retention
Gene
ENSG00000130675 | MNX1
Description
motor neuron and pancreas homeobox 1 [Source:HGNC Symbol;Acc:HGNC:4979]
Coordinates
chr7:157006479-157010651:-
Coord C1 exon
chr7:157009660-157010651
Coord A exon
chr7:157006640-157009659
Coord C2 exon
chr7:157006479-157006639
Length
3020 bp
Sequences
Splice sites
5' ss Seq
ACTGTGAGT
5' ss Score
7.94
3' ss Seq
CACTGCCCTTTGGTCCCCAGCCC
3' ss Score
7.65
Exon sequences
Seq C1 exon
GCGGCCTCCGCGCGGTCGCCTGAGGGCTGCAGCGCAAAGAACCGGGCTCCCGGGCCCGGACGCGGGGAAGCACTCGCGTGGGAGTTTGTGCGAGCGCGGCCCGGGGCGGGGCCCGCACGGAGGAGGCGCCGGGACCATGGTCACCCTCGGCTGAGTTTCCGGCGGCGACTTTGATTATTGGCAAATAACCACCATAACAATACCGAGCCCCCGGGCTTGCACCGCACGCACTGACTCCGCGAGCCCGCACACGGCCGCGTCGCCCGCCACCGGGCCCTGAGCGCCAGCCCCAAACGAGCCGATGGAAAAATCCAAAAATTTCCGCATCGACGCCCTGCTGGCGGTGGACCCCCCACGAGCCGCCTCTGCGCAGAGCGCGCCGCTGGCCTTGGTCACGTCGCTCGCCGCCGCCGCATCTGGCACCGGAGGTGGCGGCGGCGGCGGCGGGGCGAGCGGCGGGACTAGCGGCAGCTGCAGCCCCGCGTCCTCGGAGCCGCCGGCTGCGCCCGCCGACCGCCTGCGCGCCGAGAGCCCGTCGCCGCCGCGCCTGCTGGCCGCGCACTGCGCGCTGCTGCCCAAGCCGGGCTTCCTGGGCGCGGGCGGCGGCGGCGGCGGCACGGGCGGCGGGCACGGGGGGCCCCACCACCACGCGCATCCGGGCGCAGCGGCCGCTGCCGCCGCCGCCGCCGCCGCCGCCGCCGCTGGGGGCCTGGCGCTGGGGCTGCACCCTGGGGGCGCGCAGGGCGGCGCGGGCCTCCCGGCGCAGGCGGCGCTCTACGGCCACCCGGTCTACGGCTACTCCGCGGCGGCGGCGGCGGCTGCGCTGGCGGGCCAGCACCCGGCGCTCTCCTACTCGTACCCGCAGGTGCAAGGCGCGCACCCCGCGCACCCCGCCGACCCCATCAAGCTGGGCGCCGGCACCTTCCAGCTGGACCAGTGGCTGCGCGCGTCCACCGCGGGCATGATCCTGCCTAAGATGCCCGACTTCAACT
Seq A exon
GTGAGTACCCTGCGGCCCCCGTGGATGCGCGTGGCGGGAGGGCCTCGCGCATCCTCCACCGGCACCGCCTGCCCCTCTCTGCGCTTGGCTCCCAGCGAGCGGGGGAAGAGCTGCGAAGCCGCCTCGGCTCTGCCCGGGGCCTGCGAGGACTCGCCCGGACCCCCAGGCATGAGACGGGCAGCGAATTATTAAAATGGCCATGCGCAGGCCTTGCCTTCTCTTCCTCTCTTAACGGGAAGGGGCAGTTGGAGGTGTGAGACTGAGATCTAATGATTAACCCGAAGGCTGCAGGAGAAGGAAGTCGCCGGGGGAAGGCGAGCCGAGAGCGCCCTGAATTAGGCAGGCCCGGGAATGGGGGTCAGGGCTTATCACCGGGGAAAGGAACTTGGGCCAGGTCCCCCACTGGGGCGTTAGAGAGACCCGCGGCCCCTCCAGGGAGAGGGAGTGCTTCAGGAGCAGCAAACAAGAGAAATGGGCTTCGGAGGCCCGGGGAGGCAAGGCCAAGGCCCAGGGAACCCCCGGCTCTTACCAGGGCGCTGCCCTCCTCTGGAAGGGCGTTGGATCCGGGGTGCGATGGCCGAGGCAGGTGGCCTGGCTTGAACCAGCTATGGGGGGACTCTCAACAGTAGGTGCCTGCCCTGGAATCCTGGGCGCCCAACAAGGTAACGAATGCCCCTCCAAGGTGGGGCCGAGGGAGCCCCTGTTCTCCCCACCCCAGAGCCGCTGGGCTTCGGGCAGCTTCCTCTCCATCCGGGCGGGACACCTCGCCAGAGGCCTGGGCCCCTCAGGCTTTCCTGGCACACGCGGACTCTCCGGGCTGGGGCTCCGGGGCTCTGGCTCTCTGGGGCTCTGGCTCTCCCCGCTCGCCCCATCGGGGTCAGCTACTTATGAGTCGGGCCGAGCAGATGTATATGGCTCAACGCTTTCAGCCGCCGAACACCCAAACAAAGAGACCCCATTGTTTCTGTCTGAGTGGATTTGTTTAGACTGGGGAGATGCAGGCAGAGCAGGGGAAAAGCAAAAAAGAAAACAGAAATAAACACTCCAGAATTCAGATTCCTTTGCTGGAAGCTGTGGTTGTGACTAAACAGAGAAAATCTAGGACCCCAGAGGCTGGAGAAGTCACAAGAGGGTGAGAAGAATCCCTGCAGAAGGCTGTTTGCCCACAGCCGCCCCAGGCTTTCCTAGCTCAGCTCCAAGAAGGCCCCAGTGGTCACCCATCCCTCACCTGGGAGAGTCAGCCCTACTGACTGGCTGGAAGAGGGAAAGCTGCCCCTCACCTCAGACACGTCTGCGTCTGCGAATCCCCTGCCAGCCTGGGCTTAAACCCAGGGTGCCGACCCAGGGCCCATCCCTTCTGATAGAAAGCCACCAATATGACCTGCATTTCCCAGAGCCAAGGACGCTAAGTTGCCCACGGAGGGGGCTGGCCAGCCCCGGGGGCCCGTGGTCCTAGGCCTCCTAGGGGTGCTTTCTGGAGCTTCGTGGAGCCCAGGGTCACTCAGAAAATTTATTAAAGTGAGACACCTTGCCTATTTCTGATTCCAAATGTTGACCTAGAGTTGGCCAAATTTTAAACACAACCAGTCTTAAGTTCAGAAGAGGTATCTGCACCTGGCAATCCAAAAGGGCAGGCATAACCGTGCCAAAGACGGCGGAATGTGTTCTGAGAAGTCCTCCTCGCTGGTCCGGGGAAAACCTGTTTGGTTTCTTTAATTGGTTGTCTCTGCCTGTTGGATGGCATTTCCCAAATGGTCCCTCCGGAGCCAGTGGTTTAATTAAAGTTCTAATGTATTGTCAAGTTGGGAATTCGGGGCCTTGTTTGACTAAAGCAGGGGGCGTGGGCCATCCTCTAAAGCAAACTGCCCATCCCGGGGGACCTGAGCTCATCCAGGCCTGGGGCTGGCCTCCTTTCTTTCCTTTGCTTTCTTTCTTTTATTGTCCAACACTTGTCAGGCTCCTGGGAAATCAAGGGAAGTCTCGTTTTGAGGTCATAAAATTCTCTGTGATGTAACCGTGCGAAATTATGTAAATAAAGCCGGGCAGGCCTCCTTGAACACACAGAGAACCGGATCCTGCCTGCGCCTCTGCCTGTAATTTGCGTAATGAGAATTGTCCTGAAAAGGCTTCTAGTCTCCTCAGGCCTTGCCCCTGCCGCCCGCACCCTGAGGAGGGGGCATGCCAAGGAAAACATTTGGAAGGTGGGAGGGTCCCTGGTGAATACACAGACTTGGACCCTGGGTTTGGTCCTGTTCCACCTGTCCTCTCTCCCTTCCCTTCCTCCCTTCCTTCCTTCCTTCCTTCCTTCTTTCCTTCTTTCCTTCCTCCCTCCCTCTTTCCCTCTCTCCCTTCCTTCCTTCCTCTTTTTCTCCTCCTCCTCCTCCTTTTCTGTCTTAAGGAGGCAGTGCAGGGAGACCTGGAACAGCAGGACCAGCTCTTCCCAGACCTGTTTGGATCTGAGCCTGAATCTCTAGGAAGGCGCAGTGAGGAGAGGGGGAGAGATTTGGTTCTCATCACTCACTGCTCCTTTATTTTATTATTTTATTATTTTTTATTTATTGAGAGATGGGGTCTTGCTGTGTCACCCAGGGTACAGTGCAGGGGTGCAGTCTCGCTCACTGCAGCCTTCAACTCCTGGGCTTCCCGGAACCTCCCTTCCTGGCCCCCGACTGGCCTCAGTTCTCCTCTTGCCTCTGGGTCAATCCACTGCTACCAAAGCCGGCTCCTGTGGAGAGGAAGCCTCCTGCGATGGGCCCTGTTTAACAGGGACACTCAGACGTCTCCTAGACAAAAAAAAAAAAAAAAATTGGTCTCATTAACTCCAAACTATCCATTTCCACTTGGTGGTCCTGAGTCCGCATTCCTTGGGGAGTGGGCACTGATAGTGAGGGAACAGCCCCGCCCTCTGCAGGGCCAGGCCTTGGCGCTGGGGCCTTGAGTGTAGTGGTACAAGCAGCAACGGGAGGGGCTGGGGCGAGGACCGGAGCCGGCTGTGGGCCTCACTGCCCTTTGGTCCCCAG
Seq C2 exon
CCCAGGCGCAGTCGAACCTCCTGGGGAAGTGCCGCCGGCCGCGCACCGCCTTCACCAGCCAGCAGCTGCTGGAGCTGGAGCACCAGTTCAAGCTCAACAAGTACCTGTCGCGGCCCAAGCGCTTCGAGGTGGCCACCTCGCTCATGCTCACCGAGACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000130675:ENST00000252971:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.464 A=NA C2=0.120
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0004624=Homeobox=PU(95.5=77.8),PF088806=QLQ=PU(86.4=70.4)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development