HsaINT0104958 @ hg19
Intron Retention
Gene
ENSG00000011028 | MRC2
Description
mannose receptor, C type 2 [Source:HGNC Symbol;Acc:16875]
Coordinates
chr17:60741909-60743628:+
Coord C1 exon
chr17:60741909-60742310
Coord A exon
chr17:60742311-60743454
Coord C2 exon
chr17:60743455-60743628
Length
1144 bp
Sequences
Splice sites
5' ss Seq
ACGGTGAGG
5' ss Score
9.2
3' ss Seq
CCCCTGTCCACCCCCTGCAGAGG
3' ss Score
9.18
Exon sequences
Seq C1 exon
AACCCAACGTCTTCCTCATCTTCAGCCATGGACTGCAGGGCTGCCTGGAGGCCCAGGGCGGGCAGGTCAGAGTCACCCCGGCTTGCAATACCAGCCTCCCTGCCCAGCGCTGGAAGTGGGTCTCCCGAAACCGGCTATTCAACCTGGGTACCATGCAGTGCCTGGGCACAGGCTGGCCAGGCACCAACACCACGGCCTCCCTGGGCATGTATGAGTGTGACCGGGAAGCACTGAATCTTCGCTGGCATTGTCGTACACTGGGTGACCAGCTGTCCTTGCTCCTGGGGGCCCGCACCAGCAACATATCCAAGCCTGGCACCCTTGAGCGTGGTGACCAGACCCGCAGTGGCCAGTGGCGCATCTACGGCAGCGAGGAGGACCTATGTGCTCTGCCCTACCACG
Seq A exon
GTGAGGGGCCGCTTGCAGGCGGGAGGGTGGGGTCCCCGATGTCCAGGGGACTGGAGCCATGAGGGACAGATTCCCAGTGACAAGGCCTTTGGCCTCTGTGGACCCTTGGCAGTCACATGTTTAATTATAATAGGAAGCATTTTTTAATAATTAAGAAAATTAACTTCAGGCCAGGTGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACTTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGAAAAACCCCATCTCTACTAAAAATTCAAAAATTAGCCAGGTGTGGTGGAGCATGCCCATCATAGTCCCAGCTACTTGGGAGGCTGAGGAAGGAGAATCGCTTGAACCCAGGAGGCAGAGGTTGCACTGAGCTGAGATTGCGCCACTGCACTGTGCAGCCTGGGTGACAGAGCAAGACTCTGTCCCCCCCCCCACAAAAAAAAAAAGAAAAGAAAAGAAAAAAGAAAAATTAACTTCAAAGCATTTAATTTACTTTTGTAAAAATTGCAAAATACATGCTTGTAAAGTCTTCAAATAGTATACAAGTATATAACATAAAATTAAATGAAAATTCCCTTCCCCCAGGCCCACTCTCCAGGTGAAACCCCATTGTAGCCCCCCATGTTGTCTTAATGCCTGTCTTGCATGTGGTGAATGGGGACCAGAGTCACCATGTGAGGGGCTGGCCTCTTGTGGTGGACAGCCCCGTCCTGGGGGGGCCTTTCCTGGGAGACCCCCTGAGTTCCGAGATAGAACTTTGTGGGGACACAGAGCCCATGGGCTGGGTAGCTGAGCAGAGATTCCACCGGGCTCAGCCCTCTGTGGGTGACTTGGAGGCCCTCTTGCCCAGCTGGAGTTTGGATGGGATTAGGGGTACTAGGGAGCCCCTTCCCAGCCCTATGAGGTGTGCAGCAAGACCTCTCTCTGGTTCCTGGGCTGACTCAACAGCAGAAGAAGCCTTAAAGCCACTATGGGGTGCCATTGCCTCTCCCACCTGCTGATCCCTGTGAACACCCAGCACTCTGGGTTTTAGGGGATTTCTCCTGAGGGTCGAGGGGCTTGGCAGCCTCTGGTGTCCAGATGCCAAGGGCCTGGCCCCTGTCCACCCCCTGCAG
Seq C2 exon
AGGTCTACACCATCCAGGGAAACTCCCACGGAAAGCCGTGCACCATCCCCTTCAAATATGACAACCAGTGGTTCCACGGCTGCACCAGCACGGGCCGCGAGGATGGTCACCTGTGGTGTGCCACCACCCAGGACTACGGCAAAGACGAGCGCTGGGGCTTCTGCCCCATCAAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011028-MRC2:NM_006039:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.052 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0004014=fn2=WD(100=71.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCGGCTATTCAACCTGGGTA
R:
CGTGGAACCACTGGTTGTCAT
Band lengths:
351-1495
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)