HsaINT0106406 @ hg19
Intron Retention
Gene
ENSG00000198793 | MTOR
Description
mechanistic target of rapamycin (serine/threonine kinase) [Source:HGNC Symbol;Acc:3942]
Coordinates
chr1:11175453-11177143:-
Coord C1 exon
chr1:11177061-11177143
Coord A exon
chr1:11175526-11177060
Coord C2 exon
chr1:11175453-11175525
Length
1535 bp
Sequences
Splice sites
5' ss Seq
TAGGTGAGT
5' ss Score
8.83
3' ss Seq
CTGTCTTCTGTTTCTCAAAGACA
3' ss Score
6.94
Exon sequences
Seq C1 exon
GTGTGGTTTGACCGAAGAACCAATTATACCCGTTCTTTAGCGGTCATGTCAATGGTTGGGTATATTTTAGGCCTGGGAGATAG
Seq A exon
GTGAGTAATTTAATTTGGTTTTTTTAGTCTTCTTTCTCCATTGTAGTTTTCCTGAATGGTTTCATTTGGTTTTCCAATTAAATATATGGCTTTTTGGTAAATAAATATTGGTATTGTATATGTAAGGTCTCTTTTACAACATTAGCCTTAGTTCCCTATTGATTGTGATGCCATCAGAAGAATACATCAAACTAAAGAAAAGGAAAAATAGTTCAAGCTGGGTGCAGTGGCTCATGCCTGTCATCCTGGGAGGCCAGGGTGAGAGGATCACTTGAGCCCAGGAGTATGAGACCAACTTGGGCAATAGCAAGACCCCATCTCAATAAAGCCCCACATAGTTCAAGGATACTACTTTCTCCTTAGTCTGGCTTAATGTATTAAAAGCTGTATTGCAGGGCAGGCTCATTGGCTCATGCCTATAATTCCAGCACTTTGGGAGGCTGAGGTGGGAGGATCACTTGAGCCTAGGAATTTGAGACCAGCCTGGGCAGCATAGCAAGATCCCGTCTCTACAAAAAATAATTAGCCAAGCATGGTGGCATACACCTGTAGTCCCAGCTCTTTGGGAGGCTGAGGTAGGAGGATCACTTAAGTCCAGAAGGTCAAAGCTGTAGTGAGCCGTGATTGCACCACTGTGTTCCAGCCTGGTCAACAGAGTAAGACTCTGTCTCAAAGAAAAAAACAAAAATACTAAATCATATTGATTTTATTGATTCAAGAAACATTTGTCAGTCACCACTGTGCTAAGATAAATCATTTTATTTCTGTAATTGAAACCAACCAAAGTAGATCCTTCTGATATTTTTGCATAATAAGTTTTGTCCAAGTGTACTGACTGAACATGTAATTTACGAATGTTCAGAAACGGACTCACAAGAATGTAAAAAAGACTGGTTCTCTGATGTCTACTGTTTTTCTCCTGGAATCATGTCTCATGCAACTATTTGAGAGTAAAAATAATTTTACCCCACAAAAATAGTAGATTTTTGTTTTTAAAAGTCTAGCAGAATATCTGTTGATAAAAGCCAGGTGGTTGCCGGGATTGGCTCAGGGACTTAAGGAGATGAGACCCTGTTACGGCTGCTCAGTAAAAATGATAGAGCCTTGTCACCAGAAGGTGCCAGTGCTGCCAGAAATGACTTATTAGGTCACCAAAGACCTCAGAAAAGCACAGTATCTCAGTACAGTGGGACAACCTGTGATTCACACATAAGCCCACATTTCAGCAGGAGTTGGCAAACTGTTTCTGTAAAGGACCAGTTAATAGGTCGTTTTAGGCTTTGTGGGCCCTTTGGTCTCTGTCACAACTAGTCAGCTCTGCTGTCGTAGCATGGAAGCAGCCTGGAACAGTACTTAAACAAGGGAGCGTGCTGTGTGTTCCAGTAAAACTGGACTTGCAGAAGTGGAGGTGGAGGGGCTGGATTGGCTGAGGGCTATCGTTTGCCAACTCCTAGCTTACAGTATCACGTACTTATTGATTTTTTCATCCGTTATCTCTGTTGATCCCTCCCTGATCTGTCTTCTGTTTCTCAAAG
Seq C2 exon
ACACCCATCCAACCTGATGCTGGACCGTCTGAGTGGGAAGATCCTGCACATTGACTTTGGGGACTGCTTTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198793-MTOR:NM_004958:50
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0045422=PI3_PI4_kinase=FE(10.8=100)
A:
NA
C2:
PF0045422=PI3_PI4_kinase=PU(20.7=94.7)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)