HsaINT0106806 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1252653-1253390:+
Coord C1 exon
chr11:1252653-1252790
Coord A exon
chr11:1252791-1253225
Coord C2 exon
chr11:1253226-1253390
Length
435 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGG
5' ss Score
7.93
3' ss Seq
CCCCCAACCCTGGCCCCCAGGCC
3' ss Score
7.41
Exon sequences
Seq C1 exon
CCAACATCACCCTGTTCACACCCTCGAGCTTCTTCATCGTGGTGCAGACAGGCCTGGGGCTGCAGCTGCTGGTGCAGCTGGTGCCACTCATGCAGGTGTTTGTCAGGCTGGACCCCGCCCACCAGGGCCAGATGTGCG
Seq A exon
GTGAGGCTGGGCAGGGGCCTTCGGGGACAGGGCCATTGGGGACGGGGCCTGGACTAGCGCCAGGCTGCAGGGAGGGGCAGGCAGAGGCGGGCAGGGGACCGGGGAGGGGGCTGCCCCCAGGGCATGGCGGAGATCCTGGTGCCAGCGCAGGACACCAGCATTGGACCAGCGGCCCCGGAAGCAGCCAGCTGGGAGGATGGAGCGGGCAGCCCTGCCCTGGCTCAGGCCGACTTTGCACAGGGGCTGGCTTTGCACAGGGGCCGACTGCACAGGGGCGCCCCCCGCCAGGGCTTATCTGCAGAGGGTTCTGGGAGCAGAATCCTGGGACAGGGCTCCCAGCCGTTCCACCCTGTGTGGTGCCTGGAGGGATGGCAGGGGCCAGGAGCCAGGTGGGCCCAACAGTGGCCGCTGACATCCCCCAACCCTGGCCCCCAG
Seq C2 exon
GCCTGTGTGGGAACTTCAACCAGAACCAGGCTGACGACTTCACGGCCCTCAGCGGGGTGGTGGAGGCCACGGGCGCAGCCTTCGCCAACACCTGGAAGGCCCAGGCTGCCTGTGCCAATGCCAGGAACAGCTTTGAGGACCCCTGCTCCCTCAGTGTGGAGAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:14
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009420=VWD=FE(29.7=100)
A:
NA
C2:
PF0009420=VWD=PD(12.3=33.9),PF087426=C8=PU(0.1=0.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAACATCACCCTGTTCACAC
R:
ATTCTCCACACTGAGGGAGCA
Band lengths:
302-737
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)