HsaINT0106826 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1273573-1274210:+
Coord C1 exon
chr11:1273573-1273754
Coord A exon
chr11:1273755-1274038
Coord C2 exon
chr11:1274039-1274210
Length
284 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
3' ss Seq
GTGCATGTTCCCTGCCCCAGGTG
3' ss Score
8.81
Exon sequences
Seq C1 exon
GGGAAGTCATCTACAATAAGACCGACCGAGCCGGCTGCCATTTCTACGCAGTGTGCAATCAGCACTGTGACATTGACCGCTTCCAGGGCGCCTGTCCCACCTCCCCACCGCCAGTGTCCTCCGCCCCGCTGTCCTCGCCCTCCCCTGCCCCTGGCTGTGACAATGCCATCCCTCTCCGGCAG
Seq A exon
GTGGGCCCCGCCTGCCCTCCACCTCCCGTGCTGCGTGCACACGGTCTGGGTTGGCTGGAGGCACAGCCACAGTCCAGCTCCCGAGGCCCGTCTCAGTGACCCCGCCGCCAGTATCTCCAGTTGGAGGAGGCACACAGGGCCTAGGGGCCAGGCTAGCATGGGGGCCGCCCTCCTCAGGCAGGCTCTTGTGGCCACCCGGGGCTTTGGGCCATGAGGGGTGGGATGAGCCGTGGATGGGTCCCGTGAGCTGGTCCAGGTGAGGACGTGCATGTTCCCTGCCCCAG
Seq C2 exon
GTGAATGAGACCTGGACCCTGGAGAACTGCACGGTGGCCAGGTGCGTGGGTGACAACCGTGTCGTCCTGCTGGACCCAAAGCCTGTGGCCAACGTCACCTGCGTGAACAAGCACCTGCCCATCAAAGTGTCGGACCCGAGCCAGCCCTGTGACTTCCACTATGAGTGCGAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:32
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.120 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAATAAGACCGACCGAGCCG
R:
TTTGATGGGCAGGTGCTTGTT
Band lengths:
295-579
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)