HsaINT0106828 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1275322-1276110:+
Coord C1 exon
chr11:1275322-1275581
Coord A exon
chr11:1275582-1275923
Coord C2 exon
chr11:1275924-1276110
Length
342 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
3' ss Seq
GTTCCCCTGGATTCCCCCAGATC
3' ss Score
7.58
Exon sequences
Seq C1 exon
GCATCTGCAGCATGTGGGGCGGCTCCCACTATTCCACCTTTGACGGCACCTCTTACACCTTCCGGGGCAACTGCACCTATGTCCTCATGAGAGAGATCCATGCACGCTTTGGGAATCTCAGCCTCTACCTGGACAACCACTACTGCACGGCCTCTGCCACTGCCGCTGCCGCCCGCTGCCCCCGCGCCCTCAGCATCCACTACAAGTCCATGGATATCGTCCTCACTGTCACCATGGTGCATGGGAAGGAGGAGGGCCTG
Seq A exon
GTGAGTCCAGGCTGCGGGTGGCACAGTGTTGGCCCAGTCCCAACCGCACCTGGGCAGGCCGACTGCAGGCCGGGGTGACCCAGGTGCCGCAGCGATGGCCCAGTGCCCAAGACAGCTCCCAGGGGGCAGGGAAGGCCTGTGGAGCCGCCTAAGGCCGAGCGCACCCTGTGGCCTAAATGCAGCCAGCTGGAGACTCCAGGCCCCCAGGGAAGATCTGGGCTTTGGGGTGGGGGATACACAGGGGGGTCTCTGCACATGGAGGCAGAGCCCCAAAGAGAAGCCCTGCTCCCCGAGCCCACCTGGCACTGCCTCCCAGCTCAGGGTTCCCCTGGATTCCCCCAG
Seq C2 exon
ATCCTGTTTGACCAAATTCCGGTGAGCAGCGGTTTCAGCAAGAACGGCGTGCTTGTGTCTGTGCTGGGGACCACCACCATGCGTGTGGACATTCCTGCCCTGGGCGTGAGCGTCACCTTCAATGGCCAAGTCTTCCAGGCCCGGCTGCCCTACAGCCTCTTCCACAACAACACCGAGGGCCAGTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:34
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0009420=VWD=PU(51.2=96.6)
A:
NA
C2:
PF0009420=VWD=FE(37.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGATCCATGCACGCTTTGG
R:
GGTGTTGTTGTGGAAGAGGCT
Band lengths:
343-685
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)