HsaINT0106829 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1275924-1276496:+
Coord C1 exon
chr11:1275924-1276110
Coord A exon
chr11:1276111-1276270
Coord C2 exon
chr11:1276271-1276496
Length
160 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
3' ss Seq
GGTGACGCCCCCACTCCCAGGCA
3' ss Score
4.51
Exon sequences
Seq C1 exon
ATCCTGTTTGACCAAATTCCGGTGAGCAGCGGTTTCAGCAAGAACGGCGTGCTTGTGTCTGTGCTGGGGACCACCACCATGCGTGTGGACATTCCTGCCCTGGGCGTGAGCGTCACCTTCAATGGCCAAGTCTTCCAGGCCCGGCTGCCCTACAGCCTCTTCCACAACAACACCGAGGGCCAGTGCG
Seq A exon
GTGAGTGGGCGGCGGGTCCTGCCCCGGCCAGGGCTGCTGCTGGGCCTGACAACCCAGTGAGCATAGGGGAAGCCTGGGGAGGGGAATGAGTGGGGGAGGGGGGTGGGGGCTGTGAAAGGCTCCCCAGATTCCAGCCCCGCGGTGACGCCCCCACTCCCAG
Seq C2 exon
GCACCTGCACCAACAACCAGAGGGACGACTGTCTCCAGCGGGACGGAACCACTGCCGCCAGTTGCAAGGACATGGCCAAGACGTGGCTGGTCCCCGACAGCAGAAAGGATGGCTGCTGGGCCCCGACTGGCACACCCCCCACTGCCAGCCCCGCAGCCCCGGTGTCTAGCACACCCACCCCCACCCCATGCCCACCACAGCCGCTCTGTGATCTGATGCTGAGCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:35
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.237
Domain overlap (PFAM):
C1:
PF0009420=VWD=FE(37.8=100)
A:
NA
C2:
PF0009420=VWD=PD(9.8=21.1),PF087426=C8=PU(17.8=17.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCCTCTTCCACAACAACACC
R:
CAGCATCAGATCACAGAGCGG
Band lengths:
255-415
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)