HsaINT0106843 @ hg19
Intron Retention
Gene
ENSG00000117983 | MUC5B
Description
mucin 5B, oligomeric mucus/gel-forming [Source:HGNC Symbol;Acc:7516]
Coordinates
chr11:1281856-1283406:+
Coord C1 exon
chr11:1281856-1281958
Coord A exon
chr11:1281959-1282618
Coord C2 exon
chr11:1282619-1283406
Length
660 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
GGGCCACCCTGCGTCCACAGGTA
3' ss Score
8.56
Exon sequences
Seq C1 exon
ACTCCTGTCAAGTCCGCATCAACACGACCATCCTGTGGCACCAGGGCTGCGAGACCGAGGTCAACATCACCTTCTGCGAGGGCTCCTGCCCCGGAGCGTCCAA
Seq A exon
GTGAGTGGGCTCCTGGCCCTGTGCCAAGAGCACCTGCGTGTGGTGGGTCCGCCCTGGCCCGTCAGCTGGCTGGCAGCCTGCTCTGGGTCAGGAGGGCCTACGCCAGCTCCAGGAAGGAGGGAAGGGGCTCCCCAGCAGGGCTCCCCCTCTCCACGTCCATTGGCAGAAAGCCTGGGGCCGCTCTCCTAGCCAGGCCAGGGCCCGGCTGAGCCGAGCCACATGGCACAGAGCTCCCCGCTGCGAACCCAGGTCCAGGTGTCCCCCTGGGGAGGGTGGGTGGAACCAGAGCCTTCTGTGAAGCCCCCCATGGCTTGCCACTGTGGTTGGCTGTCAGCAGGAGGGGCCAGAAGGGTTGACCCTTAGCTAGAAGAGGCAGGAGGAAGGGTCAAGGGCTGCTTAGGGTCAGCAGGATTGGAGGAGCTGGTTCAGACAGGGGAAGTGCAGGCCACAGAAGACAGAGCCGGGAGCCAAGGGACCCTGGGGGCCCAGAGCTGCCCCATCCTGAGAAGGTGAAGCCTCACGTGCCCACAGAGCAGGCCACTGTGGACAGAAGGGGGCGGCCGTCTGGCCCAGGACCCCAGAGGCCCATGTGTCACCATGGCTGGGCAGAGAAACGGCGGGGCCAAGGTGGCTGATGTGAGGGCCACCCTGCGTCCACAG
Seq C2 exon
GTACTCAGCAGAGGCCCAGGCCATGCAGCACCAGTGCACCTGCTGCCAGGAGAGGCGGGTCCACGAGGAGACGGTGCCCTTGCACTGTCCTAACGGCTCAGCCATCCTGCACACCTACACCCACGTGGATGAGTGTGGCTGCACGCCCTTCTGTGTCCCTGCGCCCATGGCTCCCCCACACACCCGTGGCTTCCCGGCCCAGGAGGCCACTGCTGTCTGAGAACGTTCTGCCTCCATCCCCATGCTCTGTCCACCTGGAGCCAGGATGTGCATTGTCTGATCATGAAAACCTTGGGCCTCCTCTGCGGAGCCCCCCGGCCTGTGTGTGGCACCCCGCGCTCCGTGCTCCTGCTGCCCACCCCGTGGGTGAAACCGGCCCCAGAAGGGTGAGGGGCCAGCAGGACCCCTTTCGGGAGGGCGCCACTCAGGAGTCCTACCCTGGGAGAGCCTGTGGCCCACCTTGGCCTTGCCCCTCCCTGATGTCACTGGGACGCCCTGGAACAAACTAAGCATGTGCGGGCCTATGTGTCCCTGCCACGGCCGGAGCGCCCGCGCAGCACGGATTCCAGCTGGCCACGTCCGGCCGCTGGGGCAGACAGGCTGGTCCAGGCAAGGCCAGCTGCTGCCAGGAAGCTGCGACAGGCAAGGCGGCCGCCTGTCCATGCCTGCTGCAGGGTAACTCAGGGCTGAGGTCGCAACGGCCAGGTCAGAGAGGGGTCAGCATCCCAAAGCCCCCTCTGCTCAACCCAGCCCAGTTTTGCAAATAAACCCTGAGCATTGAGTACGTT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117983-MUC5B:NM_002458:48
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.125
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAACATCACCTTCTGCGAGGG
R:
CAGAGGAGGCCCAAGGTTTTC
Band lengths:
347-1007
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)