HsaINT0107421 @ hg19
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin, heavy chain 1, skeletal muscle, adult [Source:HGNC Symbol;Acc:7567]
Coordinates
chr17:10415725-10416101:-
Coord C1 exon
chr17:10415998-10416101
Coord A exon
chr17:10415864-10415997
Coord C2 exon
chr17:10415725-10415863
Length
134 bp
Sequences
Splice sites
5' ss Seq
GATGTAAGT
5' ss Score
9.11
3' ss Seq
CTTCTCATCTCTCATGGTAGAGT
3' ss Score
7.2
Exon sequences
Seq C1 exon
AAATGCTCCTGATCACCACCAACCCATACGATTATGCCTTCGTCAGTCAAGGGGAGATCACAGTGCCCAGCATTGATGACCAAGAAGAGTTGATGGCTACAGAT
Seq A exon
GTAAGTTATACATGAATTTTAATTTAAAATCCATTATGCATGGGAATGGCAATAACAGCCATCTATATGTGTGTAAAAGATACAGTATAAATTCTCTTGTGCCCTAATCTTTGTCTTCTCATCTCTCATGGTAG
Seq C2 exon
AGTGCCATTGAAATTCTGGGCTTTACTTCAGATGAAAGAGTGTCCATCTATAAGCTCACAGGGGCTGTGATGCATTATGGGAACATGAAATTCAAGCAAAAGCAGCGTGAGGAGCAAGCTGAGCCAGATGGCACTGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061-MYH1:NM_005963:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.277
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(5.0=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(6.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGCTCCTGATCACCACCAAC
R:
CCATCTGGCTCAGCTTGCTC
Band lengths:
234-368
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)