HsaINT0107422 @ hg38
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin heavy chain 1 [Source:HGNC Symbol;Acc:HGNC:7567]
Coordinates
chr17:10512074-10512546:-
Coord C1 exon
chr17:10512408-10512546
Coord A exon
chr17:10512193-10512407
Coord C2 exon
chr17:10512074-10512192
Length
215 bp
Sequences
Splice sites
5' ss Seq
AAGGTACCA
5' ss Score
7.87
3' ss Seq
TCTGAATTATGTTTCTGCAGTTG
3' ss Score
6.29
Exon sequences
Seq C1 exon
AGTGCCATTGAAATTCTGGGCTTTACTTCAGATGAAAGAGTGTCCATCTATAAGCTCACAGGGGCTGTGATGCATTATGGGAACATGAAATTCAAGCAAAAGCAGCGTGAGGAGCAAGCTGAGCCAGATGGCACTGAAG
Seq A exon
GTACCAAATGAATCTCCATCTGGGTTTAATGAGAGAATATAGGCAAAAATGTCCATTCCAAAATTCAAGTCTTCTTTACAGCTGAGCTCCTGATGGACATACTCAGATGTACCCACACACAGACTTTCTACAAAGTTATTTACTCAATACTATGCCCCTTTGAACTGTGGGTCCCAGAGTAAGTCATATTAGGTATCTGAATTATGTTTCTGCAG
Seq C2 exon
TTGCTGACAAGGCAGCCTATCTCCAAAATCTGAACTCTGCAGATCTGCTCAAAGCCCTCTGCTACCCTAGGGTCAAGGTCGGCAATGAGTATGTCACCAAAGGTCAAACTGTGCAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061:ENST00000226207:12
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.277 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(6.7=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(5.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGTGCCATTGAAATTCTGGGCT
R:
GCTGCACAGTTTGACCTTTGG
Band lengths:
256-471
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development