HsaINT0107446 @ hg19
Intron Retention
Gene
ENSG00000109061 | MYH1
Description
myosin, heavy chain 1, skeletal muscle, adult [Source:HGNC Symbol;Acc:7567]
Coordinates
chr17:10399267-10399866:-
Coord C1 exon
chr17:10399558-10399866
Coord A exon
chr17:10399471-10399557
Coord C2 exon
chr17:10399267-10399470
Length
87 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAAT
5' ss Score
8.88
3' ss Seq
AATGACGGTTTGTTCCACAGGAT
3' ss Score
10.09
Exon sequences
Seq C1 exon
GCATCTCTTGAACATGAAGAGGGAAAGATCCTGCGCATCCAGCTTGAGTTGAACCAAGTCAAGTCTGAGGTTGATAGGAAAATTGCTGAAAAAGATGAGGAAATTGACCAGATGAAGAGAAACCACATTAGAATCGTGGAGTCCATGCAGAGCACACTGGATGCTGAGATCAGGAGCAGGAATGATGCCATTAGGCTCAAGAAGAAGATGGAGGGAGACCTCAATGAAATGGAAATCCAGCTGAACCATGCCAACCGCATGGCTGCTGAGGCCCTGAGGAACTATAGGAACACCCAAGCCATCCTCAAG
Seq A exon
GTAAATATGTCCAACAGATGATCCCAGGACAATTGGGGTGCCTGCAACCCTGAATACATGGTGTCTCAATGACGGTTTGTTCCACAG
Seq C2 exon
GATACCCAGCTCCACCTGGATGATGCTCTCCGGAGCCAGGAGGACCTGAAGGAACAGCTGGCTATGGTGGAGCGCAGAGCCAACCTGCTGCAGGCTGAGATCGAGGAGCTGCGGGCCACTCTGGAACAGACAGAGAGGAGCAGGAAAATCGCAGAACAGGAGCTCCTGGATGCCAGTGAGCGTGTTCAGCTCCTGCACACCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000109061-MYH1:NM_005963:34
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.340 A=NA C2=0.309
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(11.9=100),PF0003816=Filament=PD(10.4=28.2)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(7.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAGGAACACCCAAGCCATCCT
R:
TGCTCCTCTCTGTCTGTTCCA
Band lengths:
167-254
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)