HsaINT0107521 @ hg38
Intron Retention
Gene
ENSG00000133392 | MYH11
Description
myosin heavy chain 11 [Source:HGNC Symbol;Acc:HGNC:7569]
Coordinates
chr16:15724161-15724799:-
Coord C1 exon
chr16:15724647-15724799
Coord A exon
chr16:15724410-15724646
Coord C2 exon
chr16:15724161-15724409
Length
237 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCCT
5' ss Score
5.4
3' ss Seq
CCTGGACGCTGTCCTTGTAGCTC
3' ss Score
6.5
Exon sequences
Seq C1 exon
GAGCTGCTTCAAGAAGAAACCCGGCAGAAGCTCAACGTGTCTACGAAGCTGCGCCAGCTGGAGGAGGAGCGGAACAGCCTGCAAGACCAGCTGGACGAGGAGATGGAGGCCAAGCAGAACCTGGAGCGCCACATCTCCACTCTCAACATCCAG
Seq A exon
GTGCCTGCCCCGTGTCCTTGCTTCCTTCATGGGTCCTCTCAACTTCTCTGCGCTGAGATCCCCCGCAGGCAGATCGCGGTGGAGTGTTGGTGCGATGGTGCTTGACCCCCCAGCTTCCCCTGCTATTGGGTTTCTCCAACGAGGAGACATGGTCTTCGCTTCTCAGAGTCTGTGGGGCCAGGGACAGGGGCCACTCATGGTCCCCCTCTCACCCTACCCTGGACGCTGTCCTTGTAG
Seq C2 exon
CTCTCCGACTCGAAGAAGAAGCTGCAGGACTTTGCCAGCACCGTGGAAGCTCTGGAAGAGGGGAAGAAGAGGTTCCAGAAGGAGATCGAGAACCTCACCCAGCAGTACGAGGAGAAGGCGGCCGCTTATGATAAACTGGAAAAGACCAAGAACAGGCTTCAGCAGGAGCTGGACGACCTGGTTGTTGATTTGGACAACCAGCGGCAACTCGTGTCCAACCTGGAAAAGAAGCAGAGGAAATTTGATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133392:ENST00000300036:30
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.824 A=NA C2=0.217
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(5.8=100),PF041569=IncA=PU(39.5=88.2),PF045827=Reo_sigmaC=PU(31.9=86.3)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(9.6=100),PF041569=IncA=PD(58.8=80.7),PF045827=Reo_sigmaC=FE(59.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAGAAGAAACCCGGCAGAAGC
R:
CTGCTGAAGCCTGTTCTTGGT
Band lengths:
308-545
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development