HsaINT0107822 @ hg19
Intron Retention
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23856738-23857132:-
Coord C1 exon
chr14:23856967-23857132
Coord A exon
chr14:23856863-23856966
Coord C2 exon
chr14:23856738-23856862
Length
104 bp
Sequences
Splice sites
5' ss Seq
AGGGTGTGC
5' ss Score
3.55
3' ss Seq
TCTGGCCCTCTGGTCCCCAGAGG
3' ss Score
8.15
Exon sequences
Seq C1 exon
ATCCTGGCCGAGTGGAAGCAGAAGTATGAGGAGTCGCAGTCTGAGCTGGAGTCCTCACAGAAGGAGGCTCGCTCCCTCAGCACAGAGCTCTTCAAGCTCAAGAACGCCTACGAGGAGTCCCTGGAGCACCTAGAGACCTTCAAGCGGGAGAACAAGAACCTTCAGG
Seq A exon
GTGTGCTGGGGGTCCAAGAGGCCAGAGATGAGTTGGTGGGAGGGAGGGCCATGCAGGGGCAGGGGGAACATAGGCTTTGAGCTTTCTGGCCCTCTGGTCCCCAG
Seq C2 exon
AGGAAATCTCGGACCTTACTGAGCAGCTAGGAGAAGGAGGAAAGAATGTGCATGAGCTGGAGAAGGTCCGCAAACAGCTGGAGGTGGAGAAGCTGGAGCTGCAGTCAGCCCTGGAGGAGGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-MYH6:NM_002471:31
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.429 A=NA C2=0.571
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(6.4=100),PF045827=Reo_sigmaC=FE(38.5=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(4.8=100),PF045827=Reo_sigmaC=PD(26.6=90.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCGAGTGGAAGCAGAAGTAT
R:
TTCTCCACCTCCAGCTGTTTG
Band lengths:
251-355
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)