HsaINT0107832 @ hg19
Intron Retention
Gene
ENSG00000197616 | MYH6
Description
myosin, heavy chain 6, cardiac muscle, alpha [Source:HGNC Symbol;Acc:7576]
Coordinates
chr14:23873920-23874336:-
Coord C1 exon
chr14:23874309-23874336
Coord A exon
chr14:23874032-23874308
Coord C2 exon
chr14:23873920-23874031
Length
277 bp
Sequences
Splice sites
5' ss Seq
CACGTGAGC
5' ss Score
5.62
3' ss Seq
TTGGTCTCTGTGGCCCCCAGGGG
3' ss Score
8.58
Exon sequences
Seq C1 exon
ATCGGGAGAACCAGTCCATCCTCATCAC
Seq A exon
GTGAGCGAGTGCCATCCTCCCACAGAAGGGACTGGGCTGGGGGCATACACGCTGATGCCTAGGGTGTAGTTGGGAGGAGAGGTTTAAGGCTGGGATTGCAGGGAGCATGGGGCACTGAGCTCTCATTAGAGGGGTGCCAGAGCAATGAACCATGTCAGGCAAATCCTGCTGGGTGCTGGGCTCTGATGGCCAGGCTGGGAAGGGGAGCATGTGATGCTGAGCCCTGTATGGAGAACAGTAGGAATCCTGAGTTTTGATTGGTCTCTGTGGCCCCCAG
Seq C2 exon
GGGAGAATCCGGGGCGGGGAAGACTGTGAACACCAAGCGTGTCATCCAGTACTTTGCCAGCATTGCAGCCATAGGTGACCGTGGCAAGAAGGACAATGCCAATGCGAACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197616-MYH6:NM_002471:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.132
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=FE(1.3=100)
A:
NA
C2:
PF0006316=Myosin_head=FE(5.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCGGGAGAACCAGTCCATCC
R:
CTTGTTCGCATTGGCATTGTCC
Band lengths:
140-417
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)