HsaINT0107854 @ hg19
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Coordinates
chr14:23889054-23890257:-
Coord C1 exon
chr14:23890167-23890257
Coord A exon
chr14:23889444-23890166
Coord C2 exon
chr14:23889054-23889443
Length
723 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
AGCCCTTTGTGTCTGACCAGGCA
3' ss Score
7.46
Exon sequences
Seq C1 exon
AAAAGACTTTGAGCTGAATGCTCTCAACGCAAGGATTGAGGATGAACAGGCCCTCGGCAGCCAGCTGCAGAAGAAGCTCAAGGAGCTTCAG
Seq A exon
GTGAGGTCTGGACACCCACGCGGGATGCTGAGTCCCTGGGCTGGTTCTGTTTCCCCTGCCCCCTCCTCTAGGGTGTCCTGTTCACAGCATTACAGGAACTGATTATGTGTCCATGGAGGCAGGCACGCAGCTATCACAGTGTGCCCATGGATACATCCAAAAGGGGTCAGGTGATCCACAGAGACCCTGAAAAGGTCACAGGCCTGGAGGGCAGAATTCCTGGCTTCCTGTCTCAGCTCTGCCTTAGTTGGGTGACCTCTGGGAGCCCACTCCAGATCTCTGGGTCTCCATGCCCTCCCCTGTTACATGGAGGTTTTTAAGAGTCCTTCGACTCTGATGGCATGACTTTCCTCCTTACTCTAGAGCAGAAGCTGTGTTAGGTCTTTAGTTGTCTGGTCAGACAAATACGGCTCTCTCATTTTCAACTTTTGTTATTTTTTTATGACTAAACTGCTTAAAATATCCCCAGAACACAGGTCTCTTTGTCCATCTTTAAGAGCAAGTTTCAACCACTTTCCTTCCAATAAAGAGCATGTAGACTGTCAGGCCCTCGCCTAAAGGAAGGCTCTTCAAACTATCTTCCCCAAATCCTTTAATTCCCACCTCTCCACTGGAAGAGCTAAACTGACTTGCTGTTCCAGAGAAGCCGAGAGCCTTTTAGAGCCGGGGGGATTCCAGTGGAGGGGTCCAGGCGGTGGGTCTGAGCCCTTTGTGTCTGACCAG
Seq C2 exon
GCACGCATCGAGGAGCTGGAGGAGGAGCTGGAGGCCGAGCGCACCGCCAGGGCTAAGGTGGAGAAGCTGCGCTCAGACCTGTCTCGGGAGCTGGAGGAGATCAGCGAGCGGCTGGAAGAGGCCGGCGGGGCCACGTCCGTGCAGATCGAGATGAACAAGAAGCGCGAGGCCGAGTTCCAGAAGATGCGGCGGGACCTGGAGGAGGCCACGCTGCAGCACGAGGCCACTGCCGCGGCCCTGCGCAAGAAGCACGCCGACAGCGTGGCCGAGCTGGGCGAGCAGATCGACAACCTGCAGCGGGTGAAGCAGAAGCTGGAGAAGGAGAAGAGCGAGTTCAAGCTGGAGCTGGATGACGTCACCTCCAACATGGAGCAGATCATCAAGGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054-MYH7:NM_000257:26
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.032 A=NA C2=0.562
Domain overlap (PFAM):
C1:
PF0003816=Filament=FE(10.6=100),PF0157614=Myosin_tail_1=FE(3.5=100)
A:
NA
C2:
PF0003816=Filament=FE(45.6=100),PF0157614=Myosin_tail_1=FE(15.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATTGAGGATGAACAGGCCC
R:
CTGCAGGTTGTCGATCTGCTC
Band lengths:
356-1079
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)