HsaINT0107859 @ hg19
Intron Retention
Gene
ENSG00000092054 | MYH7
Description
myosin, heavy chain 7, cardiac muscle, beta [Source:HGNC Symbol;Acc:7577]
Coordinates
chr14:23886712-23887615:-
Coord C1 exon
chr14:23887419-23887615
Coord A exon
chr14:23886896-23887418
Coord C2 exon
chr14:23886712-23886895
Length
523 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGT
5' ss Score
9.1
3' ss Seq
TGCCACCCTCCCCTGGGCAGGAA
3' ss Score
8.66
Exon sequences
Seq C1 exon
GCGAAGAACGCCCTGGCCCACGCACTGCAGTCGGCCCGGCATGACTGCGACCTGCTGCGGGAGCAGTACGAGGAGGAGACGGAGGCCAAGGCCGAGCTGCAGCGCGTCCTTTCCAAGGCCAACTCGGAGGTGGCCCAGTGGAGGACCAAGTATGAGACGGACGCCATTCAGCGGACTGAGGAGCTCGAGGAGGCCAA
Seq A exon
GTGAGTTCTGAGCAGCCTGACTTCTGGCTGAGGCCCCTTTGCAGGCAGGACTCAGCCCAGCCCCAGCCTCAGCAGATCCCACACAGGCGATGCTTAGCTAGTGTTTGACAACACAGGAGGACTCTGCCCCGGCCCCACCTCCTTCTCCTCTCAGGGAAGCTTTTTGCTCGAATTATGTTTCTGATCCGAATATAAGACGAACAAAAGGTTTGTCTGAGGGCAGAGTGCTTCCGTCTGGGGCAGGGCACTGTGGCAGGGAAAGGCAGTGGGGAGGGCTGCAGAAGCCCATACCTCCTCAATGTCCATAGCGCAGAGGCTGGGCCAGGGTCAGAGGGTGCCTGGGTCTCCACGCCCTGCTGGGATCCTCTGCCTGATGTTCTCGGCCCCTGGGACCTGTCCTCAGGCTTCTCCAGCTACACTTCTGAGGTTTCAAGGATTGTCTTTGAGAAGGTTCATGTTGTTTCCTCTTGTCCCCATCCACACCCTCCATCCTCCCCACCCTCTGCCACCCTCCCCTGGGCAG
Seq C2 exon
GAAGAAGCTGGCCCAGCGGCTGCAGGAAGCTGAGGAGGCCGTGGAGGCTGTTAATGCCAAGTGCTCCTCGCTGGAGAAGACCAAGCACCGGCTACAGAATGAGATCGAGGACTTGATGGTGGACGTAGAGCGCTCCAATGCTGCTGCTGCAGCCCTGGACAAGAAGCAGAGGAACTTCGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000092054-MYH7:NM_000257:30
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.394 A=NA C2=0.226
Domain overlap (PFAM):
C1:
PF0157614=Myosin_tail_1=FE(7.6=100),PF0003816=Filament=FE(20.8=100)
A:
NA
C2:
PF0157614=Myosin_tail_1=FE(7.1=100),PF0003816=Filament=FE(19.6=100),PF045827=Reo_sigmaC=PU(32.9=75.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCATGACTGCGACCTGCTG
R:
TTGTCGAAGTTCCTCTGCTTCT
Band lengths:
342-865
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)