HsaINT0108448 @ hg38
Intron Retention
Gene
ENSG00000278259 | MYO19
Description
myosin XIX [Source:HGNC Symbol;Acc:HGNC:26234]
Coordinates
chr17:36509062-36510917:-
Coord C1 exon
chr17:36510746-36510917
Coord A exon
chr17:36509136-36510745
Coord C2 exon
chr17:36509062-36509135
Length
1610 bp
Sequences
Splice sites
5' ss Seq
GCGGTGAGC
5' ss Score
8.02
3' ss Seq
CCACTCTCTTCCCCCAACAGGTT
3' ss Score
11.95
Exon sequences
Seq C1 exon
ACTCTGTCAGGACGGCAGCCTCGCTGCTGGGGCTCCCAGAGGACGTGCTGCTGGAGATGGTGCAGATTAGAACCATCAGGGCAGGCAGACAGCAGCAGGTGTTCCGGAAGCCCTGCGCCCGAGCCGAGTGTGACACCCGTAGAGACTGCCTGGCCAAACTGATCTATGCGCG
Seq A exon
GTGAGCAGTTACTCTGGCCCCTTGTTGGGGAGGACCCCGACAAGTGCTCTTCCTGTCCGGGGTTGGGCCAGACAACATCAGGCAATAGGCACAGGCCCAGGGTGGGAGATAAGACAGACTGGTTCCTCTCCCTGCTCCTCAAACCCCTGGACACATCAGGGCACAGCTCCCAGGTTTCACCAAGCAGCGTCTGTGGCCTCTTTCTGAGTGGGAAAGTTGCTACATTCCTGGCCAGAATTCAGCTCATTATTAAAGTTCAGGAGGCTGCTTTAGCCTCAGCAAGGTGAAGAGAACCTGCTCAGCTGTCTGCTGGCAAGGCAGGCCCCAAAGGTGATCTAGAGCCTTCGCAGTTCCTGCTTCAGATCCTTGGCTGAATGGGCCTCTCTGTCTCCCTGTGCCTTTGTACATCACCTAGGAGTTTGATAGATTGTGGTAAAGCCAGAGGCTCAGCCCACAGCATGTAGCACAGTGGTGAAGGTGGGGTCCTGGCCTTTTCTGGTAGATTACGTGGGTACCTCCACCCTCTGGCCATGTGGTTAAGGATGATCTCTCACCTTGAGTTCTGAGATTCTTCAGCAGGCCTTGTAAGGGCTTCAGGGGCCCAGAATCCTCTGAGATGAGCCAGAATGAGTGTATGTGTGTGCATGTGCACATGAGACCTTGGGCACCTTTCTGGGGAGAGGGTCCCCTGCTTTCATAAACTCCACAAAGAGCCAATAGCCTGAGAAGCTCTGCTGGGGGAACCAGATCGTCCGAGTTGAAAATGGTCCAGGGCAGCTGAGGCCAGACTAAATCCATTTCAGCAAGAGACTAGTTACCACTGCCTCAAGCTAATTTCAGGTCACAATTTGAGGTCAAAGGCTTTTAAAGCCTTTGCCTACAAGTCACTCCAAGATGAGCAGATAAAGTGTGATGAACACAGATAGAGTGAGCTTCTGACCACAGGACATTTGCACAGCCCCTGTTGCAAAAAGAGCCAGTTTATTTACTGAAGGGAAAAAAGTTGCAGAGCAATTACTTTAAGAAAAAATGTGAGGAAGAAACCCCTGTATAGTGCTGTACGTGTCAGCGTCTTGTGTGGTAGTCTCATCTTCTCTGGGCTGGGGCCGGTTCTAGAGTGGAGGATGCCATTGTTGACCTCGGGACTGGGGGCCCACTTGTGCAGAACTACATCAGGGGGTATGGTGGGGCCTTGAGCTCTGGGCTCCACCGGTAGAGTTTTGCAGGGGTGTTCAATGAACTCAGTTATTTACAAACCACACCCAGGCCCATCTGCCCCTTCCCAAGACACTAGCTGGGTCTCGAGCCATGTGACTGAGCTCGACTGATTCCCTCCCCAGCCTAGGAGCTGAGCTTGTCCTGTGCTCAGTCTTCCCATAAGGACATGCCAGGTTTGTGTGTACCTGGCAACATGCATGCCCATAGCCTGCATCTGTAGTAGGTCAAGACGTGATAGGCCGGAAGCAAGAGGAGAGGATTTGGTCTTTGACCTGTCAGGCTCAGAATACAAGGGCCCCCCAGGGTGTAGCACCCTGATGGGGGGAGCAATTTTACCACCCCTTTGACTCAGCCAGACCCTCTTACCAGAGTCCACTCTCTTCCCCCAACAG
Seq C2 exon
GTTGTTTGACTGGCTGGTATCAGTGATCAACAGCAGCATCTGTGCAGACACCGACTCGTGGACCACTTTCATAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000278259:ENST00000610930:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(54.7=97.2)
A:
NA
C2:
PF0006316=Myosin_head=FE(6.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCTGTCAGGACGGCAGC
R:
CTATGAAAGTGGTCCACGAGTCG
Band lengths:
246-1856
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development