HsaINT0116941 @ hg19
Intron Retention
Gene
ENSG00000095319 | NUP188
Description
nucleoporin 188kDa [Source:HGNC Symbol;Acc:17859]
Coordinates
chr9:131765596-131767500:+
Coord C1 exon
chr9:131765596-131765733
Coord A exon
chr9:131765734-131767425
Coord C2 exon
chr9:131767426-131767500
Length
1692 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGG
5' ss Score
6.92
3' ss Seq
CTCTCCTGTGTCTCTCCCAGGTC
3' ss Score
12.47
Exon sequences
Seq C1 exon
TGCCTCAACGCAGTGAGGACAGTGCAGAGTCTGGCCTGCCTGGAGGAGGCGGACCACACCGTGGGTTTTATTCTGCAGCTCTCTAACTTCATGAAGGAGTGGCACTTCCACCTGCCTCAGCTCATGCGTGATATCCAG
Seq A exon
GTGGGGGCCCAAGATGGTGTCTTGGAGTCTGGGGTAATGCTTGGAGACAGGGAGGCTGTGAGGTCTCACTGGGGCACTCCTAGTGAATTGCAGGATGTTCCTGAACGGGGGCTTTTCCCTTGGGGAGCACAGGGTTTGCTGTCATGTGCTTACTCTGGCTAAATGTTTCCTTCCATAGTCAAGGGCAGCCATGTAGGTTAAGAATTTGGACTTTTATCAGTTAGATCTTGGTTCAGATCCCTTAAGAATACACTTGGGGCCGGGCATGGTGGCTCACGCCTGTAATCCTAGCACTTTGGGAGGCAGTCAGGAGTTCGAGATCAGCCTGGCCAACATGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCGTGGTGGCACGTGACTGTAATCCCAGCTACTCGGGAGGCTGAGTTGGGAGAATCGCTTGAACCTGGGAGGCGGAGGTTGCAGTGAGCTAGGATCGAACCATTACACTCCAGCCTGGGTGACAGAGCGAGACTCCGTCCCAAAAAGAAAAAAAAAAAAAAATGGCCGGGTGCAATAGGCTCACGCCTGTAATCCCAGCACTTTGGGAATTCAAGGCGGGAGGATCATGAGGTCAGGAGCTCGAGACCAGGCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATAACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAGTCCCAGCTACTCAGGATCGGGAGGCTGAGGCAGGAGAATCGCTTGAACTCAGGAGGTGGAGGTTGCAGTGAGCCGAGGTCACGCCACTGCACTCCAGCCTGGTGACAAAGTGAGACTCCGTCTCAAAAAAAAAAAAAAAAAACTAAACTAAACAAAACCAAAAAAACACACACAACTGGAGCTGGGAACCAGCTGGAGAAGGGAGGGGTGAGGAAGGAACACAGGCTCCAGAGCCAGGCAGGCTTCTCTTATCTGCTGGTTGTATGACCTTGGCCAAGTCACTTGTTACTTGTAACCTTTTATTCTTTTCCTATAAAATGGAATCAGCCATAATCCTCATCTTATTTTATTTATTTATTTATTTTGAGACAGAGTTTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGTGCCATCTCGGCTCACTGCAAGCTCCGCCTCCCGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCCGCCACCACGCCCGGCTAATTTTTTGTATTTTTAGTAGAGACAGGGTTTCACCGTGTTAGCCAGGATGGTCTCGATCTGCTGACCTCGTGATGCGCCTGCCTCGACCTCAAAAGTGCTGGGATTACAGGCATGAGCCACCGCACCCGGCCTCATCTTCTTTACTTTAGGACCTTACAATATACCAGGCACCTAGCTGGGTCTCAGGGAGACAGTCCAGTCCTGAGCCCTGCTGGCCCAAGTTTGTAGCCCTGAGTACTTAGTGGCTATAGGGGCTTTAAGCTGGAAAGTGGCCAGGGGAGCATGAGGGAAGGAGGGAGAGAAGGGGAGCATGAGGGAAGGAGGGAGAGAAGGGGAGCATGAGGGAAGGAGGGAGAGAAGAGCAGCAGCGAGTGAGGAGCGCATGGGTGTTACATGGAGGGCTATTGGGTTGGTCTGGTTGGGTGACTGGGCTGCTGACAAGAGAATCCGCTCATCTCTCCTGTGTCTCTCCCAG
Seq C2 exon
GTCAACCTGGGTTACTTGTGCCAGGCATGTACCTCTCTCCTGCACAGTCGAAAGATGCTGCAGCATTACTTACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000095319-NUP188:NM_015354:38
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.008 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCAACGCAGTGAGGACAGTG
R:
GCTGCAGCATCTTTCGACTGT
Band lengths:
199-1891
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)