HsaINT0118197 @ hg38
Intron Retention
Gene
ENSG00000173391 | OLR1
Description
oxidized low density lipoprotein receptor 1 [Source:HGNC Symbol;Acc:HGNC:8133]
Coordinates
chr12:10160786-10166957:-
Coord C1 exon
chr12:10166712-10166957
Coord A exon
chr12:10160926-10166711
Coord C2 exon
chr12:10160786-10160925
Length
5786 bp
Sequences
Splice sites
5' ss Seq
CAGGTATTG
5' ss Score
8.35
3' ss Seq
AGATATACTATCCTTCCCAGCTC
3' ss Score
3.59
Exon sequences
Seq C1 exon
TATCCCAGGTGTCTGACCTCCTAACACAAGAGCAAGCAAACCTAACTCACCAGAAAAAGAAACTGGAGGGACAGATCTCAGCCCGGCAACAAGCAGAAGAAGCTTCACAGGAGTCAGAAAACGAACTCAAGGAAATGATAGAAACCCTTGCTCGGAAGCTGAATGAGAAATCCAAAGAGCAAATGGAACTTCACCACCAGAATCTGAATCTCCAAGAAACACTGAAGAGAGTAGCAAATTGTTCAG
Seq A exon
GTATTGGGAGAAGGGTGGGTAAGGAGACATAGTGGAAGCTTTCTGTCCAATCATAACTATTTTTTGGAAACAATTCTGGGCTCAAAATTGGTCTATTGTTATGCATATCATTATTCATTCATAATGTTCTATACAAGAAGTTCTCAATTTCTTTTTCTTTTTCTTTCTTTTTCTTTTTTTTTTTTAGATGGAGTTTCGCTCTTTTGCCCAGGCTGGAGTGAAGTGGTGTGATCTCTGCTCACTGCAACCTCCACCCCCTGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCCAAGTCGTTGGGACTACAGGCTCCCATCACCACGCCCAGCTAATTTTTGTATTTTCAGTAGAGACAGGGTTTCACCATGTTGGCTAGGCTGGTCGCGAACTCCTGACCTCAGGTGATCCACCCATCTTGGCCTCCCAAAGTGCTAGGATTACAGGCATGAGCCACCGCTCTCGGTCAATTTTTTATTTATTTTATTATTATTTTTTAATTTTAGACGGAGTCTTGCTCTGTCACCCAGGCTGGAAAGCAGTGGTGTGATCTCAGTTCAATAAGCTTCTGCTTCTTGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCCAAAGTGCTTGGGATTACAAACATGAGCCACCATGCCCAACTAATTTTTGTACTTTTAGTAGAGACAGGGTTTTGCCATATTGAACAGGCTGGTCTCAAACTCCTCACCTCAAGTCATCCGCCTGCCTCAGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCACCCGGCAAGAAGTTCTAAATTTTTAATCAGAACCACCCTATGCTGTGTCAAATCCTTGAAAAATCTGATTTAATTAAGCATACCTTTTGGTGGATTTAAGTTTTCCTTCTTTATAAGAGCCTCTTCTTTTTAAAATTTTAGTTTTGAGATTTTTCTTTCTTTTTTTTTATTTTTTGAGACAGTCTCGCTGTGTCACACCCAGGCTGGAATGCAGTGGTGTGATCTCAGCTCACTGCAACCTCCACCTCCTGGGTTCAAGTGATTCTCTTGCCTCAGCCTCCCTAGTAGCAGTTTTGACATTTTTCTTGAAGAATTCTGCCACCCCCACCCCATTCCATAGATCCTTATCTCTTTCCATTCCAATGCATTTTAATCACTGTATTTCTTTTTCTAAGGGATCTTTTTGTCCTTGCAACTGTCTACCCCTAACTCTACATTAGCTCACTCTGTGGCATTATTTCTTAAAGTGTACTACATCAACTTATTTTATTTGATTTCAATTTTTGGAGATGGAGTCTCGCTCTGTCGCCCAGGCTGGAATGCAGTGGCCTGATCTCGGCTCACTGCCACCTCCGCCTCCAGGGTTCAAGCAATTCTCATGTCTCAGACTCCCAAGTAGCTGGGATTACAGGCACCCACCACCACGCCCGGCCAATTTTCTTTTTTTTTTTTTGAGAGGGAGTCTCGCTCTGTCCCCCAGGCTGGAGGGCAGTGGCACATTCTCGGCTCACTGCAACTTCCGCCTCCCGGGTTCGAGGGATTCTCCTGCCTCAGCCTCCCGAATAGTTGGGATTAGAGGCACCCGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGTGTTTCACCAAGTTGGCCAGGCTGGTTTTGAACTCCTGACCTCGGGTGATCCGCCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGTGCCGGGCCCATCAATTTAAATAGAGCCAATGGAGGTAGACTGGCTTGCAAGCCTTACGCAGATACTTCAGATTAGACAAAAATATGAGGAGTCCAAGAAGTCTATTTATATAAGAAGAAATGAGTTAATTTTAGCCGTCTAAAGGGACTCAGAATCCAGAGGCAGGCAGAAATAGTAGCATCTATAAGAAGACTATGATGTGAACTCTGATATTGTTACAGAAGCTACTGTATTATTTGGTCTTTCTGCAGTATGTCATTACATCAGGTATATGGTTTTAGGCATAGGGAGAGTTAAAAGGTGTGAGAGAGAGTCATTCAGAGGTACTTTGTTTCCTTGGAGGTGCGTAAATTAGTGCCCTATTGTCAGGATTAGAGAAAAACTTCCTCTAATAAACAGAGATCTCTCTAGCTTCTTGCTTGCACAATTTACTTAATCTCAACCACATAATTTATTTGAATAAAGAGCATATAATAATAGTTCACAGATACCTAAGCTTTTCCTTGATAGGTGGAACACTGAGACCCGGATAAAGTGAAATGATAATAAAAAGTAATTTTGTGTAAGGTTTTGCAGTTTGTAAATCCCTTCACTATTTAGAGGTCATTTACATTTTCAAAATTAGCAGAAATTTTTGAACAAAATAATTTTTAGCAAGTGTCAAACATTTTTAATCTCTTTAAAGTTGGAGCTTGCAAGGAAATGAATATACCACCTTCAAGAAGGCTTAAAGGGAGAAAGTTTATCTATTAAGGATAGGAATGTTTATAAAAGCGGACATAACCACGTACTAACCAATGGTTTATATCACAGGCAAGGCCAGAAGAGAATTTTGTCTTTATCAGTTGTATGGGATTAAATCTACATCAGGACCATTCAGAACTATCTCCCAGAGATGCCCTGGATGAACAACTAATAAAAAACAATAAGTGATATGTCTGATGCTGGCAGATATACCAAGTAACATGTTCCATTCCTTGACAGTGTCAGATAAAGGCTAATTAGTAGAGATAGCAAATAAAGTTTTGCCTTTCATCAAAGAGCATTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTAGAGTGCAGTGGTGCGATCTAGGCTCACTGCAACCTCCGCCTCCCGGAGTCAAGCAATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCGCCTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGTCAGGCTGGTCTCGAACCCCTGATCTCGTGATCCACCCACCTTGGCCTCCTAAAGTGCTAGGATTACAGGTGTGAGCCACCAGGCCCGGCCCACCAAAGAGCTTTGAGAAGTCTTTAAAAAGTAATACTAAAATACCACATACAGAAAAAAAAAAAAAGCCAAGTTTTTCCAGTTTGAGGCAAGTTTTATCTTTTTTACTAAAAAGTCTGTGGTCTTCAATGTATATATGAGGAGGGAGAGATGCTGAGAGGTTATTATATGTTTGCTTTAGGCCAACGAGCTAGTGAGATGCAGGGCCTTTGCAGGAATAGACTTCACATTTAGCAATGGAATTTGTGGTGATTCTCAAACTTTACTGTATGTAAATAGATTGTTAAAAGTGGCAGATTACAGATTTACCTCAAGATTCTGTATCAAAATGTCTCGAGAGCAGCACCGAGAAACACTTCCTCAAATGGTTTTAACTTAGAAGTTTGAAAGGTAGTATGTTATAGTGGTGAAACACCCAGACTCTAGAGTTACATTATCTAGGTCCAGATTCTTCTCTATTTGTCAAATGAAGAAAATGACTGGAACCTATCTCACAGAGATACTGTGAGGATTAAATGAGTTAATACCTGTACAGTACTTCCAACAGTTTCTGGCACATAGTGAGTGATATTTGTGTTTGTTAAATTATATAAAAAATAAACATAGTAAGTGATATTTGTATTGTTATATAATTTAACAAACACAAATATCACTTACTCTGTTTATTTTTGTGTACACACACACACACACACACAAAGAAATACAGTAAGTTTAAATACTACATTTTGTAATGTGTCCTTCTTACTTTGTCATAACTGGGAAAACTTGCCCAGACTGTCTTTTTAGTCCACAAAAAACTTATATACATCTAAATATATTTTTTGAGACAGAGTCTTCCTCTGTCATCCAGGTTAGAGTGCAGTGGCATGATCTCAGCTCACTGCAACCTCCACCTCCTAGGTTCAAGTGATCCTTCCACCTCAGTCTCCTAAGTAGCTGAGACTACAGGCGCACACCACCACACCCAGTGAATTTTTGTGTTTTTTGTAGAAATGGGGTTTCGCCATGTTGCACAGGCTGGTCTGGAACTCCTGGCCTCAAGCGATCCACCCACCTCAGCCTCCCAAAGTGGTGGGATTATAGGCATGAGCCACCACCCCCAGCCAAAAACGTACATATATTTATATTTACATAATATGATGGGGTTAGGCAAACTAAGAAGTAAGAAGCTTGCATTGACTGCTTTCAACTTGGTCTCTTTTTCTTTTCATAAGCATCAGTTTGGTGAAAAATCAACTTAGTGTTTTGTATGCTCTTTCTCATTCACTTTTTTCTGTTTTTCAGTCCCTCCTATTTTCTCCTCTCTGATAAAGCCTACTCTTATACATTTATTTAGTGGTTTTATGCCACAGTGAGAATGAAATTAAAATGCTGCCTTTCTCAAAGATTTTAATTTTTCACCTTTTGGTTGTAGTGTAGACCAGAGTACTTTGTTTCCCCTTAAGGAGATGGGAGAGATGATGATGATGATGGTGATGATAGTGATGATTTGAGGGTTCCTGAAAGCATCCATAAACATGTAGACATTGGTATATTTTGCCTATTGTCTAAGTCCTGTTTTTGGTTTGGTGGACTCCCTGTGAATTTTGCTACTGAAAATCTCCTTATTTTCTAAAATCTCGTTTAAATTGAGATCCTCGCTTTATATTAATATACTATTTTCCCTAGAACAACTCTGTACAAAAGAAATATAGTATGTGTTTTTTATATATATATATATATATATCATTAAAATTTCTAGTAACCACATAAAAATGAAAAAGAAGCAGATAAAATTAATTTTAGAAACACATTTTATTTAACCCAAGATATTTGAAATATTATTTCAATACTAATCAGTATAAAAATTTTTAATGGACTATTTTACATTCTTTTTCTTTTTCAAATTAAGTTTTCAAAATCTTTTGTGTGTTTTACACTTATAGTACATCTTAATGCAAACTAGCCGGGTGTGGTGGGTCATGCCTGTAACTCCAGCACTTTGGGAGGCTGAGGCAGGAGGATTGCTTGAGGCCAGGAGTTCAAGACCAGCCTGGACAACATAGCGAGACCCTGTTTCAATTAAAATAATTTGTTTTAAGAAATGCAAACTAGCTATATTTCTAGTACTCAAGAATCACATATGGCTACTGTATTAGACAACACATGTCTGAAAGCAAGACACATAGTATTTAAGCCTAGATTCATTATTCAAAGATATGAAATTTTAAAATGCATAGCATTACTTTTTAAAAATAGCAGAATGGCTATTAAATATCTGTTCTCCCAACCCTCACTTTCTTTATTTCCAACACAACTTTAAAAAATAGATCAGTTTCTAAAATTACATGCTAGCTTAACTTGCTTTTCATCAGGGGAAGTGAAAATGCTAAATGAGAAGTACATTTAGGTTGCTAAAATCAGTATGCTTTCTTTCTTTCTTTTTTTTCCCAAAAAATGAAGAAATAAGGACTCTGAGGCTATTTAGGTATTTGCAGAACCTGGGTAAAATTTTACTTAAGAAGTAGTGTGGGCAGGGCGCGGTGTCTCACGACTATAGTCCCACTACTTTGGGAGGCTTGGCCTACATGGTGAAACCCCATCTCTACTAAAAATACAAAAACAAAAACAAAAACAAAAATAAATAGTATGCACGTGAGAGAACTAAGGGGATCATTGATTTAAGAACTGCAGTACTGCTTTTACACAAACATAACTGACTGATGAGATATACTATCCTTCCCAG
Seq C2 exon
CTCCTTGTCCGCAAGACTGGATCTGGCATGGAGAAAACTGTTACCTATTTTCCTCGGGCTCATTTAACTGGGAAAAGAGCCAAGAGAAGTGCTTGTCTTTGGATGCCAAGTTGCTGAAAATTAATAGCACAGCTGATCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000173391:ENST00000309539:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.364 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF039389=OmpH=FE(56.2=100),PF101864=Atg14=FE(53.9=100),PF083915=Ly49=FE(70.1=100),PF145841=DUF4446=FE(75.9=100),PF148511=FAM176=PD(77.9=97.6),PF041117=APG6=FE(66.7=100)
A:
NA
C2:
PF043759=HemX=PD(8.6=27.7),PF083915=Ly49=PD(12.6=34.0),PF130941=CENP-Q=PD(30.9=80.9),PF054737=Herpes_UL45=FE(79.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development