HsaINT0120871 @ hg19
Intron Retention
Gene
ENSG00000167081 | PBX3
Description
pre-B-cell leukemia homeobox 3 [Source:HGNC Symbol;Acc:8634]
Coordinates
chr9:128691934-128697886:+
Coord C1 exon
chr9:128691934-128692124
Coord A exon
chr9:128692125-128697750
Coord C2 exon
chr9:128697751-128697886
Length
5626 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGT
5' ss Score
9.8
3' ss Seq
TTCTTTCACTCTTGTCATAGACG
3' ss Score
7.57
Exon sequences
Seq C1 exon
GCATGTAATGAATTTACTACACATGTGATGAACCTTCTCCGAGAACAGAGTAGAACACGTCCCATTTCTCCAAAAGAGATTGAAAGAATGGTGGGCATCATCCATCGAAAATTTAGTTCCATTCAGATGCAGCTCAAACAAAGCACTTGTGAAGCAGTTATGATTTTAAGATCAAGGTTCCTTGATGCCAG
Seq A exon
GTATGTGAAGCCATAAATCTATTGCATGGCTTTCCCCCGTCTGTCACTCCTTGTGTATTATTTTCTGTAAAACTGACCAGTTGGTCTTAGATTCTTTTGGCCATATGAGTCTTTTGTACAATGGACAGGTAATTCAACTCATGGTTCCTGTGCTGTCAAGCTTTCCTGTCTGGGAATGGTAATGTGGGTTAGCTGCCAGTTTAGTGACTCAGGAAATGAATAGGATTAGTGTCTCTGCTAATGACTTTAGGAATATGTAGCCTTTCCATTCTGATGCTAAAAGGTATTTTTAAGGATAGTTTTCTGCATATAACTGTTTTAACAAGGGGTATTTTGTAAGAATTTCTTAATGTTACACGGGTTGTGCATAATATGGGAAAATACTTGGAGATACTGATACTCCTAAGAAGGAAGTGGCATTTCAGTTAATAGCAGTTACCACAAAACTCCAGAATCTGTATTTCCAAATCAAGAAAGAAAGCCTACCATTTTTCCTGTAAGGATGAAAATTTCCCTTTATCTGAAGCTTTCCCCAAGTTTCACAGGAGTTAGGTAATATATTGTATATGGTAATAAATTGTCTACAGTGACCTACTGAGTGACAGAACAGAAGAATTGTCAACGTCATAGTGTACGCTGCCCCTGTAGGGATGCCTCTCGGGGCATTGCTAAAGCTTATGATGAATCTGCAGCTTTGGAAAGAAGTTTCTATTTTGTTTTTCTTTCTTCTCCCATGGAATCTGACAGAGGTGATAATTATCATCCAAATCTCACAGTATTAAAGGAAATAACTAAGATAGCTTCTCAACTGGAAAACAAAGTGTGTGGAGCATTTTCAGTGTTTTTCATTTTAGCTCTTTATTTTCATCTCAGTTCCTGCCCATCCTTTTGTACATGGGCTAGCACAGTACCTACTAGTCTCCCTGTCTCCAGTCCTACTGCCCTCCAGCCCATCCTCCATATCCCTTGTCTGTTTCTATAACATCACCGTGCTACCATGATTGCTTTGCTTGAAAACCACAGTAGCTTTCCAATGCTCGATACATGCATACTTCACATATACACTCCTTAACCTGACATTTAAGGCCTGTTCCTGTCTGCATTACTTCTTTGTTGTTGTGAAGATTTTATTATTCTTTTTTCTATTTTAAAAATGCCAAGCTCACTATGGAAAGTTTGGAAAATATATGGAATAAAAGGATGAAGGATAAAAGTTAACCTCATTTTTATTACCTAAAGAAAAAATCACTATAAATGTTTTACAATATTCTCTCTCTTTTTGTTTGTTTGGGGGCTTTTTAAAAGAAATATTTCTGTGATGGGTCAATATGCATAATTTGGTCTGCTTTTTAAAAAATTTACCATGAATACATGAACATTTTCATGTAGTATAAGCTCTAATTATTAATAGCATTTTAACAATTGAAGTTACCAAATGGATATAAAATAAATAATGTCCTTAGCATTCCCTTATGCATTCCCTATGCACTCCACCCAGGCTGGAGTGCAGTAAATGATGCTATCATGGCTCACTGCAGCCTCGACATCCCATGCTCGAGTGATCTTCCTGCTTCTGCCTCCCGAGTAGCTGGGAGGCATTTGCCACCATGCTCGGATAATTTTTGTATTTTTTGTAGAGATGGTGTTTCACCATGTTGCCCAGCCTGGTCTTGAACTCCTGAACTCAAGCTATCCTGCCTCCCAAAGTGCTGGGATTATAGGCAGGAGCCACCATGCCCAGCCAACTATTAATTTTCATATAATTTCTTCCTTTCTTCCTTCCTTCCACAAATATTTATTGGTACTGAGGATATATTGGTAAACAAGACAGATTAATATACTTGCCCCAATTGAGCTTATATTCTACTTGAGGAAACAGACAGTAAACAGGTGAACAAATATACCATAACATTCTATTTAATAATGTAATTAAATGTAATAGGGTGATAAGTGGTATGCAGAAAAATAAAGCAAGTCAAGGGGAGAGAAAATGGAGAGGGTACTATTTTAGATAGATTTTTATTTAAACTAACATTTTAATGAAAATCTTCATTGATTGAACCTTTTTGGTCTTTAGGATTATTTCCTAAGGATCAATTCTTAGAAATGGAATTATTAGATCTGAGTTTGAACATTTTCAGTGTTCTTATTTATATATCACTAAATTGTTCTTTCCTGTGTTTCTTCCAAAATGAAATGCTTCATGGAATTATGTTTCTACTGCTTAGAATTCCTTCTTTTCCTAAGTCTAACCACTTACTTCCCTGGCTCCCACAACAAACTGTCTCTCTAAGCTGGTTACCAGTAATGAGTCATCATCTGTGAGGGTATCTGGAATGGAGCCCGGAATGGAACCAGTGCTTGTACTTGTTGGATCTAGTGAGATCTTGCTCATCGTTCCGGATCTGGTCTAAATGCTCGCTTTTCAGAAAATCCACCTTAATCACCCTGCTGGACTAGCCCTTCCTTCCCTTGAACACTTATACTATGTTTACGCAACTATTCAGACTGAAAGTCATGTAGGCTCCTTTTTCTTGTAGTTTTTCATGAACATTTCTTCTCTCCCTTAGTAAGCCACAGTGTCATTGAAAGCAACAGCCAAGACTTACACATTTGCATTCCCCACAATTCTAGCAAATGACTTACATGTTAGAGGCTACCAAAAATAATTTATTGACTGGCCAGATGAATGAATAATTCCACTTAATACTTTGTAACAGCTCAAATCAGGGTTAGAGAGGTAGCATCAGACGACAAAAAACATTTTAAAATTATTTGTCTAATTTGAGCATTTTAATAAAAAGCATTATGTAACAAAGATAGTAAAACATGTCTGATAGAAAGAAATATTTTCTAACATAATTGCTATCCTTATTTCTGCTGATACTTTCCCATTCTTGTCAACATGCATGCTTATTTTTTAAATAACTGCATTCATAATGTATACACCTAAATGATTTATTTTTCTTCCATGAAGAGAAAGTGTATTAACAGCCTAAAGTGAGCAGGGCCAGAATGAGAGAGTGGCAGAGCTTGGAGCAGAGTCTCTTCTCCCATAGAGATTGCTGTTAGTAATGTTGTGATGCTGATGGAACACAGGCCTGGACTGATGTGCCACTGCACACTGGCCTGAGGCATAGCCATTTAGAGTGTGGTGAACCCTGGGGGAGTGAAACTGAGGGGAAATGCTTAATGGGCATTTTCTACAGGATGCTTTCTAAAAAATAAATAACGTATAAGACCAAGTTCTCTCCTGTGCCTTCAAGTGAATGCAAATACTGAGCTTTGGTTCCATCTATTCTTGTAGTGCCTCCCAGCAAGCCCTCTGCACTGAGAAGGCAAGGGGCTCTGCTCTAGGCAAACATGCTCAGTCAGATATATGATTCCCTTGCTCACTCTGACTTCCCATGCTCATGTTTGCTTCATAATTGGACAAGACGAAGCATGCACCAATGCAAAACATTTAAGAATAAATTTGTGTAGGTCCGTCTCCTCTTCCAGTAGAAGTGCTGTAGTTTGGACACAGCCAGAATGTCCGGTGAGCTATTCCGTTTGTTCTCTGAGGTGTTTTGAAGTTTGTTAAAAACCACCCCTGGGCAAAAGTGATGTGAGCCAAACTTCTCTTTGCTTTTCTAGATATATTTCTTTTTGATCCTCCTTTCATACGTCGCTATTTCCCAAAGAAATGCACTTGTGTCATCTATTCCCATCTACCCTGGGCCTTGCTCCTGGGCACCAGGAGCTTGCTTACATATAGTGGAATTGAGTGGAGTGGCTGAAGCAGGGATACAGGGAGGGACAAGGAGGGTTGGAGCAGGCAGGTGCATATCTAAGGGGGCAGCTATCACTCAGCTTTAACCTAGAGCTGCCTTCTGAGAACATGGGCCCAGTACTGTTGGTATCCCAATTTTTCATAAGAAGTCAGAAACCTAGATTTTTATGAGCAGGTAATTACTGTGTGGTCTCAATAAATAATGTCTATGGGCCAGATAATGTCCATAAATTTGACATTTTCAGTATCTAGTCTAGACATTACCCATGCACCTACTCATCAGAGTGTACCTCTTCAATGTGCTCTCACCTCGGGACCTTGTCTTTCTTTTCAAGCAACACATGACTCCTGCAAAAATGCTAACTGTTCTTCTTTTTGGTGCATTTGTCTTCGTTCCGTTCCTTCCCTGTCTTCCCTTACCACCTCCCCATCCAGTTCATCATCAAATCCTGTTGATTTTAATCCCCAAATACATCTTGAATCTCATCTTCATCCTCTAGAAAACAATAGTTTAACCCTCCTAAAAATTATTGAAATTAAGACATTTCAGGACTAAAACCTGAGTTGTTTTGATCAGACCTAGATTTCTTGCTCCCTTGACTCTCCCTTAATGTTGAAATGTAGATCACATACTTAACCTGCCATATGAATGACACCATTTTGACTAGAAGAATCTCATAGAGTGCATACCTATACAACAGCCTACTGACTCTGTGTTTTCTGACTGTGGGATATCACAATTGAGAAGAATTAAGATTATTTGGAAGAAAGTATTAAGAAAATTATCTGGGGAAGGTATTTTCTAATTACTGGAGTACTTAATTGAAAGTGAATTCTGACAAATGATAATTTTCAGGCTGGAATTCTTTAAAATCTTAATAACAAAACCCAAATATAAATGACATTTTTGCTACTTGAAATATGTTGTTAATAAATGCTTGATCTTTTGAAAGTCTGTTACCCCCTTCCCAACAAAAACAAAAGATAACTTTTTGTTCTCTCCTCTTTGCTTAGTGAAGGAAATCATACCTCAGTCCAGGAAGTTGCTTAAGCAGAAAAACCTAGAAATCCTTCCCAATGCATTTTTTTTTTCCTAAACTTCCTTCTCTATCTCCCTCACTCACTCCTCCCATTCAATACATCATCAGGTCCTATTGCTTTTACCTTTCAAGTAGATCTTGAGTCTTGTTTTCATTGCTCTCACCTTGTGCCAAGTTACTATCATCTTCATTTTGACCAGTGCAATCATCTCCTAAAATGGGCTTTGCAGTTCCTTTCATGCGCTCCTCCACCTATTCTCAGCAGTCAGAATGATCTTTTAAAAACATAAAACTTAAAACCTTTAATAGTTTCCTATTGCACTCAGCATAAAATCCAAAACTTCTTGTAGCTCCACTGAGCTTCTGTAATCTGCCCCCTGCCCATCCTTCCAGACTCATCTCACACATTCCCTGTCTTTTACGGTGCCCCAACCTGCTCTAACCCTTTAGACAAGATATTTCTGTTTCAGAACTCTTCCTCTGCCCAGTCCTCTTCCCTGTAAGCTCTCTGATAGACCTTGTTTGTTCTCACTGGATCTTCATTGAATATCTAAAATATTAGGTCTTCAAAGAATGAAGCACAATAGTCTGCTTCATAGTCTGGTATTTTTCTCAGTGATCCTACATCTTAAAATGAGTTGGATAATGCCTTGGAGGATGTCTAGAACATAACGTATAATATCACAGAAATAAATTAGACCTTAAGGATGTTTAAAAAGAGAAATCTACTTTTTTGGTATCATCCTAATTAACCCATCCCTCTTAGGTTAATGCTGATTGTAACTGCAATTATTTTCTTTCACTCTTGTCATAG
Seq C2 exon
ACGGAAAAGGCGTAACTTCAGTAAACAGGCCACAGAAATCTTGAATGAATATTTTTACTCACACCTCAGCAACCCCTACCCCAGTGAAGAAGCCAAAGAGGAGCTGGCCAAGAAATGCAGCATCACAGTGTCACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167081-PBX3:NR_024123:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.204 A=NA C2=0.021
Domain overlap (PFAM):
C1:
PF037928=PBC=PD(48.4=95.3),PF040917=Sec15=PD(50.8=48.4),PF070286=DUF1319=PD(60.5=81.2),PF083976=IMD=FE(57.8=100),PF0004624=Homeobox=PU(0.1=0.0)
A:
NA
C2:
PF057036=Auxin_canalis=FE(26.3=100),PF0004624=Homeobox=PU(75.0=97.8)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)