HsaINT0121856 @ hg38
Intron Retention
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165336123-165339358:-
Coord C1 exon
chr6:165339278-165339358
Coord A exon
chr6:165336212-165339277
Coord C2 exon
chr6:165336123-165336211
Length
3066 bp
Sequences
Splice sites
5' ss Seq
CAGGTATGA
5' ss Score
9.46
3' ss Seq
TGGTTTTTGCATGGAGGCAGCTT
3' ss Score
-1.57
Exon sequences
Seq C1 exon
GGTGATGAAATGAAGAAATTGGGAATACAGCCTATTCCTATGATGGACAGAGACAAGAAGGATGAAGTCCCCCAAGGCCAG
Seq A exon
GTATGAATTATTAAAGTAAATTGTAATTGCTAAAGCCAAATAGTTTAAGGTGGGCATAAAATCATACATAAATGGAAAGCATGTCATCATATATTATGTTAAGGGAATGGGTTATTCCAGGCAGATCTGGTGATTAATATAGAAACTTCAGAAATTTATCTTACAAGATTGAGAACTAGAAAAAGAAAAACTGTTTACCCTGAATAATCATCTACTCAAATGAGCCTTCACTTGCTAAGACACTCAGAAAAGTAGACTCTAAAAGAGTTTATACTCTTAATCTGAGTTTGACGGCCAACTCTAACCACTGATTTTGTTCCCAAGGCTAAAAGCCACAGTGAGGAATCCTGAGGGTCTGGCTGCCTTGTGGACTGGAGGGACTTAGTGCTCAGAGGACAGAAGCTAGAACCACTTGAAACCTTCTCCATTTAGATGGAGTAAGACCAAGGTTAGGAAATCTCTGTGGACTGAAAGAATTCATACTACCTTGGCCACGACTCCTTTCTACAGCTGCCGTTGCAGTAAATAGGCTTTCTTTTCTGACTTGAAATAGAGGGGGTGGATGAATTTGAATTGTTTTATTTTTAACAAGCAGAAAATATTTTGTCATTGGCTAAACAAAGATATTTTTGGAGAGTTACATTATAGATTTTAATTCAGGTTCATTTTTTTCTGACAAATAATGCTTAGTATTTTAGTACATTTTATGTTTTGTCTCAACATAAATTGACATTAATTATCCTCTTTTCAGGTCATACTACATAATTTATTTTGCTTTTGAATGTTTTGAGAGGTCTTGTGCCTCGCTAGTTTTGCACATGTGTATGTGTGGTGTCATATATTTCTGAGAGTATGGCTTTCGTTAACTGTCTCATCTTCTAATGGCATAACAAGGAAGTTAGTTGTGGGCAAATAAATAATTATGATACAGATAAGTTTAACAAATGTTTAAAAAAGTCCACAGGATGGTGGTTTTTGATAAGTTCTCAAATTTCCCTACTTTATTTAAAATTGATTTATACAAAATTTAGACAAGTCCACAGCTCACAGAGGGTACCAGCACAACAAAGAGGCTGAATGAATGGCCATTGCCTCCACTTATGTCCCTGGCTAGGTTTTCTGATGGCATGGTCACTTTTCCCTCTTGATTAGAAATGGATCCTGAATACCTATCGTGTTTACTGCAGGTGTATTTTGAAGTTTTTGTCGCATTTTACCACTGTTCATGGAATTTTCCCATATATGGAGTCACAGCTGTTAGTCATTCCTGTTCGGTGTCTGCTTTTCATATTGTATTTGAGAAGTTCTTTCCCATCTTGAGAGTAAATATATTTGCCTATATTTTCTTTAGTTTCTTCTTGATTACTTTCCATTTGATTTATTGACTTGTTTGGAATGTATCTTGTTATATTATTTAAGATAGGGATCTACAATTTCTTTCCTTCCCAGTAGTTAACAGTCATCCCAAGAATGCATGGTATAGCTGGAAATTTCTCATTGATGCTGTCAGCATATGGGTTTTGCTCTAGTGTTTTTAACTAAGATAATCGTTTGTTTTAGAATAGTTTGATTTTCATTTACAGCCTAATAAAGGTTTAAAGAAAAATTTCTATGATCAGTTCATATTTTACCAACCATATTGCTTCTAAATAGTTGATGACTGTGAAATTATTTGCCATAATAATGAAATACTCTAATTTCTAATATTAGTATCTTTTCTGGGATCTTGTGCCCCATGACATCTGTTAAATATTAGAATAAGAAAGTCTCTGCATGAGCCATAAAGTTAAAAATGGAAATAACACAGGCGCTATTCTAGTAAGAGTGCTATGACGATAGACTTTATAACAGGAGAAAGCAAAAAGGAATAAATTTGATCCTTCTGTATGCTTCGATGCATATCACTGAAGTTCAGTACTTTCGAGAAATTGGTAAGCTGTGATTTGGGGTCACCTCTTCTAGAGAGCTATTTGTCTCGTACATGATGCAGCCACTTGGCCAGTGACTTATGACTAGACAAGCTGTGTTATCTGGCTGATAGTCACATATCTTTTACATCTGGACTTCAGTAAGCCAGTCTTATTTGCACAGTGACCCAGAATTCCTAATAAAATATTATTTATGTATTATTTAAAATACTACAGATTTTTAAACTTTGAAATGTGATATATTGGAAAAACAGTAAATGGGAAGAGCTGTGATAAAACCAATGACATTTATTTTAGTTCAAATAAGAGGGCTGGGAGGATGAGTAAATATTGGGACACCACACAAGGCACCAAAGCCAAGAGTAACAGACAAGCAGAAAGCACTGCTGTAAACCTGAGCACGAGGGCGGAAAGAGCCATATGTATGAAAGAATAGCAGGCTTTACGTTGAAGTGTCTGCAAGAAAGCACTAAAGGTGACTGGAGATAACACAGGACTTGAATGATCAACTGACTGATCTATTAGCGAAATGTCATTTAATGTACTTGGGTCTTAGATTTCAGTAGGTATTTTTTTTTTTTTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCGCCCAGGCCGGACTGCGGACTGCAGTGGCGCAATCTCGGCTCACTGCAAGCTCCGCTTCCCGGGTTGACGCCATTGTCCTGCCTCAGCCTCCCGAGTAGCTGGGACTACAGGCGCCTGCCACCGCGCCCAGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCTTGTTAGCCAGGATGGTCTCGATCTCCTGACCTCGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACCGCGCCCGGCCAGATTTCAGTAGGTATTAACCTTTGTAATATGTTTTGAATCTTCATGTGTTTTATTTCTAGAATCCATTTTAATGCATTTTAAAATACAGTCTATAATAGTATTCATGGAACCCAGATATCACATACAGCAAAACTAGAACATGCAATTTTATAATTAGGCCTCAGAAACAGAACAGTCACTTAAGAAATATAAATATCACTGGAATTGCTAATGTGCACTTTTGTTTCTTGTCCGTGGTTTTTGCATGGAGGCAG
Seq C2 exon
CTTGGGTTCTACAATGCCGTGGCCATTCCCTGCTATACAACCCTTACCCAGATCCTCCCTCCCACGGAGCCTCTTCTGAAAGCATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541:ENST00000366882:21
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.333 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=FE(11.0=100)
A:
NA
C2:
PF0023314=PDEase_I=FE(12.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development