HsaINT0121956 @ hg19
Intron Retention
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A, cGMP-stimulated [Source:HGNC Symbol;Acc:8777]
Coordinates
chr11:72291930-72292523:-
Coord C1 exon
chr11:72292401-72292523
Coord A exon
chr11:72292018-72292400
Coord C2 exon
chr11:72291930-72292017
Length
383 bp
Sequences
Splice sites
5' ss Seq
CGAGTGAGT
5' ss Score
8.49
3' ss Seq
CCTTTCTGCCTCTCAACCAGGGA
3' ss Score
8.52
Exon sequences
Seq C1 exon
GTTCTGTTTGATGGTGAAGAAGGGCTACCGGGATCCCCCCTACCACAACTGGATGCACGCCTTTTCTGTCTCCCACTTCTGCTACCTGCTCTACAAGAACCTGGAGCTCACCAACTACCTCGA
Seq A exon
GTGAGTGGCTGCATCTCCCCCACATCTGGCAGCCACTGGGGTCCCCTCCCTGGGACAGGGAAGCACCCCCTGTGTGTCAGGCACTTTACACGCACTGCCTCATGGGATCTTCTTAGCCCCAGGGGACTAGAGGGGAAGGCTGTGAGCCCCATCTTCCAGGAGGGGCTTGCTCACAGCCAAGCAGCTAGTGAAGACTGAGCCTGATTTAAACCCGGGTCTGCTGGGCTCCAAACCAGTGCTTCTTTCCAGGAAGGGAACCCAGGTGTTCCAACCTCCTGTCCCAGTGGCTCCTGGGCATGTCATCTCCTGTCTGTCCTCTTGGGGATTTAGGGAGGGAACTGTGGGCTGACCTCTTTTTTTTCTCCTTTCTGCCTCTCAACCAG
Seq C2 exon
GGACATCGAGATCTTTGCCTTGTTTATTTCCTGCATGTGTCATGACCTGGACCACAGAGGCACAAACAACTCTTTCCAGGTGGCCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642-PDE2A:NM_001146209:24
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(11.3=64.3)
A:
NA
C2:
PF0023314=PDEase_I=FE(12.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTTGATGGTGAAGAAGGGCT
R:
GAGGCCACCTGGAAAGAGTTG
Band lengths:
206-589
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)