HsaINT0123718 @ hg19
Intron Retention
Gene
ENSG00000087157 | PGS1
Description
phosphatidylglycerophosphate synthase 1 [Source:HGNC Symbol;Acc:30029]
Coordinates
chr17:76410960-76415756:+
Coord C1 exon
chr17:76410960-76411108
Coord A exon
chr17:76411109-76415626
Coord C2 exon
chr17:76415627-76415756
Length
4518 bp
Sequences
Splice sites
5' ss Seq
CAGGTTGGT
5' ss Score
8.08
3' ss Seq
TGTCTGTTCCTCTTCCTCAGGAG
3' ss Score
10.65
Exon sequences
Seq C1 exon
GCCTCTGGCTGTACCTGGCAGGGAGCAGCCTGCCCTGTCTCACGCTGATTGGCTCTCCTAATTTTGGGTACAGGTCAGTTCACCGGGACCTGGAGGCCCAGATTGCGATCGTGACGGAGAACCAGGCCCTGCAGCAGCAGCTTCACCAG
Seq A exon
GTTGGTCGCAGCAAGTGGGATTTCCCAGGGCGCTGAGGGTGTGGCTGGGGGCCCAGGCTCACCCGTGCTGTGGGGCTGCCCTGAGAGCTGTTTCCTGAGGCAACGAGTGAGACTCAGAGCAGAGCAAGAAAGACTCTGGGTCTCCAAGAGTGCAGTGATGGGTGGCTGAGCCTTGGAAGATCATGCCTGTGACTTCCCAGACGCGTTGCACCCCACGTCCTGGGGACTTTTTCTTTCTCTGCACTAGGGGAGACCACCATTTTCTCCCTGGGACCTTTTCCTTTTAAGACAAAGGGTCAACTGTTAAAGGTTCGGCATTGGGGCTGGGTGTGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGTCGAGGCAGGTGGGTCGCCTGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACCCCACCTTTACTAAAAATGCAAGAAAGTAGCCGGGCATGGTGGCGGGTGCCTGTAATCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCTAGGAAGCAGAGGTTGCAGTGAGCCAAGATCGTGCCATTGCACTCCAGCCTGGGCAACAAGAGCGAAACTCTGTCTCAAAAAATAAAAGGGTTCAACAGTGGTTTCGGCCCTCGTTTGATAATAGTAGCCCATTTTCTCTTTGAGGGAGATAAAAGAAGGTTACCAGGAGTTGGTGAATGCTTCGGGATGACCCTCTATTTGATGACCTGTGACAGTGTGGTTAGACTTTTGAAATGGGAGCGTGTTACCCTTTTGTCTGAGACCTCGATGGTGCCTTGGGCTCATGAATTCGTGACCTTTGCAATAACACTTTTCCATGGAAGGCACCAACTTCCCTTTTCCATTCCTGGAGATGCAGATAACACTGCCGCAGGCCAGAGCCCAGAGGCATCGGACGGTAACTTTGTGAAGCTTTTATGCTCCAGGGTTTGGGAATAACTGTTGCAAAATTGTCAGAGCCTTTGTTGATGGACGAGGAAATGGTCACTGATGTGTTCCCTGGGATCTGTCCTCCTGCAGCCTGGGAATCTTGTCAGTGACTGATTGATTGGGGCCTTGGTGCCAGGAAAGGCTTCACGACCACGACAGGCGCAAGAGGAAGTGAAGCGGTCATCCTCTGGGTGGGCCAGTGGGGTAATGGGTTTGCTCAGGTTTCTTCCTACAGTGAGGTTTACAGCAAATGACTGAGGAAGCCCCCACAAGCTGAGAGATTCCAGTAATAGGGTGACAAGCTGGCCTTGGAGCCAGGCTAGTGGGAAAGACCTGAGCCTGCAGCTTTCAACAGCGGGCTTTCCTGGACTTCTACTTCAATTGCAGAGAGCCGTTCGCAGAGACTTCCACTGTAGCTCTGTGCCAGGGCGGTAGAGAGTCCTTGGTGACTTTGGCCAGGGGCCAGGATGGGTTCTGCGTGGATCTGAGTTGCTTGGGGGAGCAAGTCCTCCAGGCCTGTGCCTGGGGTCCTGGTACTGACCGTCCTCCCCCACTGCCCTAGTAAGGGCACTGAACCCACATCCTGGATCTTGAGAAAAGCTGGGGCCGCCTGTGGTTAGCAGCTGCTTTCTCAAATGACATATTTGGGATATTTTCTTTTTCTTCCCAAACCTGAATCTCAGGGGCTTTTGCCTGTGGGAGGGTGGAGGGTGGTAGGTCTGCTACTGTAGCTCTTCCATTCTTTAGGGATAGACTGATTTCTCTGCCTGTGAAACGCAGAAATATGTTTCCAGATAATTCCACCTATGCTTATATACTGGGACGGCAGCTGCTCTCCTGAGCCCTACAGTGCCCGGTCCCTAGAGGCCAAATCCTGCTGGGACTGCCCAGCCTCTAGCCTCCCCACAACCCAGAAAGTCCCTAAAGCCCCAGCCACCGTGGGCTCCCTGCTCTCTGAAGCTGTCTCTGGAGATCTGCTTGGGAATTCAGGGAGGGGCCCTCCTATTCATGTCACATTGGGCACTGGGAATGGGGAGATATTTTTATCAGAATCTGAAGCCCCTCCCTCCACTTAGTACATACAATAAACACTGAAAGCTTCCTGGTTTTGTTCAGGGAACACAGTTTACCACTTGTGACCCAAGAAAGACTCCCTCGAACAGCGTCGTAACCTCGTCAGCTGACTTCCTTCTCCATCCCTGTTGTGGAGTCTGTGAGGAAACCTAAGTGTTTCTGGTAATTTAGTTGCAATCTTGGCCGGGTATTCATTTGAAGACACAAAGCTGGAGCCAGGTCTGTGGAGACTCCTGCAAACCAGCCCCCTGAGACCAGAGCTGGCTCTTCCATCAGGCACGTCCAGCCAGGGATTGGGACCTCAGCAGCAATTAGGAGGCCCCATGTCTGTGACACGCGGGGCTGCGGGGCTGCTCAGTTGGGAGTGTGGCATGGACCCACGATGGGGCCCACTGAGCATGGGACGGGGGCAGGGGGTAATGAAGTCGGGGCCTGGCTTTCCCCAGCTCTTGATGGGAAAAGCCAAGGCCACATTCTGTAGGGTTCTGGAGTGTGGGGTGACCCCTTCCTGACCCCCCGGGGCAGAGGAGTTGCCAGGGCTGTGTCCTCCCTCCCGGCCTCCTGAGCAGGGAGTGTGCCACTTTGAGTGGCACAGGCCACCGCTGCTGCTGTCCTGCGGTTGGCACTGTGCTTCTGTGGTCATCACCTGTGGTCCTCACGGCGGTGTGGATGTAGGTATGGCCCGGACATTACGGTGGAGAGCGCTGGAGACTCAGTGGAGGAGAGAGGGCTAGAGTCGCGGTGCAACTGTGTGAGCGCTGCCAGGCGCCCCACTGAGGACACTGAGGAGAGAGCACTTGGAGGGCAGACTCTTACAAGAGAAGCTTTTCAAAGATCCCAAACACCATTTCGGACAAAGCATATATAAATTTTTTTTTTTTTTTTTTTTTAATGGAGTCTTGTTCTGTCGCCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGTAACCTCTGCCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTATGGGTGCATGCCATCACGCCCGGCTAATGTTTGTATTTTTGGTAGAGATGGGGTTTAATCACGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAAGTGATCCTCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCGCCCGGCCGCATATATAAATGTTTTTAAACCTGTTTTTAAATATGAAATTAACATGTGTTCACTATAAAAATTAAGAAAAACGGAAAGAAACTAACCCTTTCTGTAGGGAAAACCACTGAAGCCATTGTGATGATTGGCCGCCTGCCTTCTGTGTACAGCGCACGGAGGCACAGCTTTAAGCATCAGATGACGATTCTGTCGTGTGTGTGTATTTCGTGTCCAGCTTCCTTTGCCTGCCGATTTCTGGGCACTTTCCCATATGATTAGGTCAACACTCTTCTCATGGCGAAAACTGGTTTGTCATATGAGTTGTTAATAAGTTCGTGGTGAATGCTGGTTTGTCATATGAGTTGTTAATAAGTTGACTGTTGGACATTTAGGTGGTTTCCAGTTTTTCCTTGTTATAAATATTGTGATAAATATCTGTATATAAAAATCTTAGCGCATAGTGATTTTCTTGGGGTAAGCTCTTGCAAAGGGAGCTTTATAAGGTTCTTGATACCTGTTGCCAGAGCTCACTCTAGAGGATGACTTGTCCCCCTTGCCCTCAGCACTAAGCGTTCATCAGTGTGGGGGATAATGACATCACAGATGTCATTGGCACAAATTGGCTTTGTGCCAATTTGATAGAAGAAAAACTGTGTCTCATTTAAAAAATACCTCATTTTAATATGCATTACCTCGTTTAGTGAGGGTGAACATTTAAAATATTTTTTCCACCAGTTATATTTCTTCAACTCTAAATTGAAGAAATTTAGAGTCCTTTACATGTCTTGGTCTTAAAAGCCTTTTGGGTTTTTTTTTTGAGACAAGGTCTCACTTTGCCACCCAGGCTGGATTGCAGTGGCAGCATCACAGCTCATGCAGCTTTGACCTCCCGGGCTGAAACCCTTGCCTACCTCAGCCTCCCAAGTTGCTGGGGCTACAGGCACACACCACCATACCCGGCTAATTTTTAGAATTTTTTCATAGAGATGATGTCTTCCCTGTGTTGCCCAGGGTGGCCTCAGACTCCTGAGCTCAAGCGATCCTCCTGTCTCAGCCTCCAAAAGTGTTGGGATTATAGGCTTTAGCCACTGTGCCCAGCCCTTAAAAGTCTTTAGGAACACGGCTTCTTAGCTTTTCTAAGGAATGTTTGACAGTGGCAACTTGTAGGGCCTGGCCTTGCCTGCCACCAGAGCACCCTGGGAATCTCTGGGCCAGGTAGACATGGGAAGTCAGGGTTTTCTGGGCTGGCCTGAGGGGCTGGGCTGGGGCCAGCCGGCCATGTGGTGTGGTGCTGGAGGGGACTCCTCACTATTCCTGTCTGTTCCTCTTCCTCAG
Seq C2 exon
GAGCAAGAGCAGCTCTACCTGAGGTCAGGTGTGGTGTCCTCTGCCACCTTCGAGCAGCCGAGTCGCCAGGTGAAGCTGTGGGTGAAGATGGTGACTCCACTGATCAAGAACTTCTTCTGAGGACAGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000087157-PGS1:NM_024419:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.101
Domain overlap (PFAM):
C1:
PF130911=PLDc_2=FE(28.8=100)
A:
NO
C2:
PF130911=PLDc_2=PD(2.9=12.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)