HsaINT0124914 @ hg38
Intron Retention
Gene
ENSG00000011405 | PIK3C2A
Description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8971]
Coordinates
chr11:17131916-17135029:-
Coord C1 exon
chr11:17134819-17135029
Coord A exon
chr11:17132039-17134818
Coord C2 exon
chr11:17131916-17132038
Length
2780 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
3' ss Seq
GTTAAACTTTCTTTTCTCAGTTA
3' ss Score
6.53
Exon sequences
Seq C1 exon
GCTCACTTAATCCTGAAAATCCTGTTCAAGTAAGCATAAACCAATTAACTGCAGCAATTTATGATCTTCTCAGACTCCATGCAAATTCTGGTAGGAGTCCTACAGACTGTGCCCAAAGTAGCAAGAGTGTCAAGGAAGCATGGACTACAACAGAGCAGCTCCAGTTTACTATTTTTGCTGCTCATGGAATTTCAAGTAATTGGGTATCAAA
Seq A exon
GTAAGTAACTGTTTAAGCAGCCAGGCATGGTGGCTTGCACCTGTAATCCCAAGGCTTTGTGAGGCCACAGTGGGAGGATTGCTTGACCCCAGGAGTTGGAGACCAGCCTTGGCAATGAGACCTCATCTCTACTAAAAAGAATTTTAAAAAAATTAGCCAGTCAGGCACGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCTGAAGCGGGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGACAAACATGGAGAGAACCTGTCTCTACTAAAAATACAAAATTAGCTGGGTGTGGTGGCACATGCCTGTAATCCCAGCTATTTGGGAGGCTGAGGCAGGAGAATCACTTGGACCCAGGAGGTGGAGGTTGCGGTGAGCCAAGATTGCACCATTGCACTCCAGCCTTGTCAACAAGAGCTAAACTCCATTAAAAAAAAAAAAATAGCCAGTGGTGGTGTGCACCTGTAGTCCCAGCTACTCAGAAGGCTGAGGCAGGAGTATTGCTCGAGCCAGGAAATGAAGACTGCAGTGAGCTATATCATGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCTGTCTCAAAAAAATAAAAAGAAAATATGTGCAGCTTTATCTAGCAACTATTCTGATCTTGTAAAATGTCAGCAACCAGTTATCTTGGTGTTTAAATGACTAACCAGCAGATACCTTTGTTATTTTCTTAAAAATTACAGAGGTATTTGAAGCACTTCCAGTAAAAAAAATGTAACTCTTTACATGCCAAAAGCAGGAAAATATAGCAGGAAAACAGAGCAAATATAGCAGGAAAACAGAGCAAATGTCAGTTAATTAGGCAATTTAAGACTGGTGTTCGTTCATTATTATTATTTTTTTTTTTGAGATGGAGTCTTGCATTGTTGCCCATGGTAGAGTGCAGTGGCGTGATCTCGGCTCACTGCAACCTCTGATTCCAGGGTTCAAGCAATTCTTGTGCCTCAGCCTCCCCAGTAGCTAGGATTACAGGTGTGCACCACCATGCCTAGCTAATTTTTGTATTTTTAGTAGAGACGAGATTTCACCTTGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTGCCCACCTCGGTCTCCCAAAGTTCTGGGATTACAGGCATGAGTCACCACACCCAGCCGCCAGTTTTACTTTATTTGAAAATCAATGTATGAACTGAAAAGTCAGAAATATTTTTAGTGAAATAGTTTTATAGTAGCTTAATGCTATAAAAAAGTCTACTGAAGAAATATCAAACCTAAGTTTTGCTTAAATTGGGCTTTAGATTAAAATATAATAATTTAGTGACTTAAAAGTGATGTTTTAATTTATTCAATAAATATTTATTGAGCACCATCTGTGGGCAGTATTCTTAGTACCGGGGATTCAGTAGTACAAGGCGGCAAAAAACCTGTACTCTTCTGGAACTTGGATTTAAATGGATATTGATGGTATCTGAAGGTATTTCATTACAGGGATAATAATCTTCACATTCTCCATAGGCACACACACACACACACACGTTTGTACATAGACACACACAAATATACATAGGGACACTAATGAGGTGAACAAATACCCAGTAGAAGACAATACAGAAAACGGTGATAAAAATAGAAAGTAAGTGAATAAAATGCTGACATAAATAGGAGTAAATGGAATAAAGTTGAGAAAAATAACCAAATAGTTTGCTTAGGGGTATTGTGTGAACCAACGAAATTTGATTTGAATTAAATTTAGAATGATAAATAAATTGTATATATGAACAGAGTGGTTAACATGTAAGGCTAGCAGTAAGTTAGATTAAGTAGAATACAATTTTATTGAATCTAAGACTCCTGCTTTACAAGATTACCTGACTGTATCCAACCAGCTGTGTACTTGGCAATTAGTGGCTGAGTCACTGCAATCTAATGAGAGAATTCAATAGCATCTGTCCCCATAAATGGAAGACTCCCAATAGACTAGGAAGATTGGCTTGATGCAAGTCAGGCACATGCTTAGCTGACTCTATTTCAGTAGCTTAGCAAAGGAAAATGCACCTAGGGAAGGTAATGTTTGTACTCTTTCTACCTAGAAATGAATAAATACATTATTCAGTGTTGTTCAACTAAAATCTGAAGCTAATAACTAACTGAGCACAAAATTAAAGTAAATTGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCAAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAATACAAAAAATTAGCCGGGCGCGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCAGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCCGCAGTCCGTCCTGGGCGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAATTAAAGTTAATTATTCAGCTGGTGTTATTATGACCATGCTTTAAACTGGGACCTAGGAACTTACATTCCCCTTTTTATCCCCTTTACCAAACCTCTTTTCTATTTTCATAGAATTTGCAGTGGTTAAATTTCAGATGGACTTCTAAAAACTCAAATGAAAGGTGACCAGATTATTTCAGATATTAGTCTCTTTGGAGGAAGAACTGCTAATGTATTTGTATTAGTTAACTAATTTGTATTATCATGATAGAAATCAAGTTAAACTTTCTTTTCTCAG
Seq C2 exon
TTATGAAAAATACTACTTGATATGTTCACTGTCTCACAATGGAAAGGATCTTTTTAAACCTATTCAATCAAAGAAGGTTGGCACTTACAAGAATTTCTTCTATCTTATTAAATGGGATGAACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405:ENST00000265970:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.149 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=PU(0.1=0.0)
A:
NA
C2:
PF0079219=PI3K_C2=PU(29.1=97.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development