HsaINT0124938 @ hg38
Intron Retention
Gene
ENSG00000011405 | PIK3C2A
Description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha [Source:HGNC Symbol;Acc:HGNC:8971]
Coordinates
chr11:17147517-17148787:-
Coord C1 exon
chr11:17148667-17148787
Coord A exon
chr11:17147629-17148666
Coord C2 exon
chr11:17147517-17147628
Length
1038 bp
Sequences
Splice sites
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
3' ss Seq
TAATTAATATATCTTAACAGTAA
3' ss Score
5.58
Exon sequences
Seq C1 exon
TGAGTTCTACTGTAGAAATCATTATAATGCAAGCCCTTTGCTGGGTACATGATGACTTGAATCAAGTAGATGTTGGCAGCTATGTTCTAAAAGTTTGTGGTCAAGAGGAAGTGCTGCAGAA
Seq A exon
GTAAGTTTATTTAACTACTGAGCAACATCCTTGGAAATTTCATTTTTAATGGTTTAATCTAGAAAAATTTCAAGTTAAATTTATAATGCAGAAATACATTGGATCCTATTGAATTGATTTATTGAATCAATAAACTTTTATTGAAATATATAATGTCTAAGATGTCATGTCTAAGACAGTGGTGGGGTTTCAGAGATAAGTGAGACATTGTATTCCCTTAAGGAGCTTGTAGTCTTTACAGGAAGAGTTTCAGGCAGTTGGTTAATAAGTGATATAATGGGTCTTTCTTACTGTAAAGAGTCAATAGTCACATCATTATAGACTATATTCCTCTTGCAACATGCACTGTTACTTTATGCACAGTAGTCAGCTGTGATTTCCTTTTAGTTGCCTGAAATAATCATTATATGAATCTTTTTCTTACCCAGGTATTTATTATATCTTTTTTTTTTTTTTTTTGAGACGGAGTTTCACTCGTTACCCAGGCTGGAGTGCAGTGGCACAGTCTTGGCTCACCACAACCTCCACCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGCACCACCACGCCTGGCTAATTTTGTATTTTTACACAATACAGCCTGTTGGTCAGGCTGGTCTCGAACTCTCGACCTCAGGTGATCCACCCGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTCAGCCACTGTGCCCAGCCTTGTAATTCATTATATCTAGCATTTAGTCCAGTTGTTTTACAGATTTTATTCTCCTAGGCTGCTAGAAATGCCCTGTCCCGATTTTTCTTATTTCCTTCTTCATCTTTGTCTTCATCTTCTTTCTTTTTTACATTGACTCTTCTCGTACAGAATAATTTCTCTGTTTAAATGCTCAGACTTGATTTTAAAACTGTCTCTGTTTCACCATTCTCTTCAATTTCTGATGCAGGTGCAATTTAAATTTTACCCTCACCTTTATAATTTCTAATTTGAATAGAATAGTGAATAATTAATATATCTTAACAG
Seq C2 exon
TAATCATTGCCTTGGAAGTCATGAGCATATTCAAAACTGTCGAAAATGGGACACAGAAATTAGACTACAACTCTTGACCTTCAGTGCAATGTGTCAAAATCTGGCCCGAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405:ENST00000265970:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0079413=PI3K_rbd=FE(38.5=100)
A:
NA
C2:
PF0079413=PI3K_rbd=PD(27.9=76.3)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTAGAAATCATTATAATGCAAGCCC
R:
TGTTCGGGCCAGATTTTGACA
Band lengths:
223-1261
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development