HsaINT0125007 @ hg19
Intron Retention
Gene
ENSG00000139144 | PIK3C2G
Description
phosphoinositide-3-kinase, class 2, gamma polypeptide [Source:HGNC Symbol;Acc:8973]
Coordinates
chr12:18491360-18496294:+
Coord C1 exon
chr12:18491360-18491482
Coord A exon
chr12:18491483-18496260
Coord C2 exon
chr12:18496261-18496294
Length
4778 bp
Sequences
Splice sites
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
3' ss Seq
AATTTTACATTTTTTTTCAGAAT
3' ss Score
8.7
Exon sequences
Seq C1 exon
GAAAACGTGTATAATATTATTGAAGAAGTTAAAAAAATATGCAGTGTTCTAGGGTGTGTGGAAACCAAACAAATTACAGATGCAGTAAATGAACTAAGTCTAATTCTTCAGAGAAAAGGAGAG
Seq A exon
GTAAGTACATTCATTTATTACACAGTAGTTTTAAACCTGAGTTCAATACTTAATTAAGGAGAGTGAAAGACTTTTTACTAACAACTATATTTCCGTGTGTATGTTTGTGTGTATCTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGCATGCAGCCAAACAGTATATTTCAATTGTTTGGGGGTATTGGCAGCTTGAGTCTATTATGCCAAATAGATCTGATTAAACTATAAGAACACTGATTACACCTTTGAAGTTTGTAACCACCTTATAACTTCAGGTGATATTGTAATCAATCCTACAATCCTACCTAAATGAACGTAATTATATAATAATCACATGTAAGTGTTTGTATAGATTGTTAATGGTTCTCATGTATACGAGTGTATACAGGCATTAAGTGTCATGTTTGTATGGATAAGCATATTTATAAAAAAGAAAAAATCAATTTTTGTGGTATCTTTTGCGAATTTTGCAGTGCACACTGCCTCCATGATTTCTGTGTGACTTTCTATGGATCCCACATCATGATTTGGTGGGCTTAAAAAATGGGCATTATGTGATTTTCTTTTGAATTCTCAGAAATCTGATGTAGACCTGTAAGTGATTATTTTCCAAGAAAAATATTACGACATCTGGTTACAATAAATTCATTTATCTTATTATTAGTTTAGCAAATGATAAAGCAGAAAGATATGATGATAATAACTAGCATTTGCTAGTCCATTGTAATGTATAAAATAGTTTGACATATGCATTACCTCACTGAATTTAATTTTTATTTTATCTCAATAGATGCTCACAGCAATGTCATAAAGTTGGTATTTTAATGTTCATTTCACTATGAAAACTCAACACTTACAGTGTGTGTGTGTACAGAGAATTAATAAGTGGCAAAATACAGATTTGAACCTAGGCCTCTACACACATTACAGTGTATGTGAAACTTTCTAAGATAGAGTGAATACATACATTCTCTATCTGCATGGTAAAGAACAAGAGAAATTCTACTACTTTTGAATATGCCAATCTTGAAATTTTCAAAAGACTGATTTACAATGTAGATAATCATATTACCAAACAGAAATAGTCATGCTTACTGCTTATTGTTTCAAATAGATAAGTGGGTATGAAAATTCAGTAGTTTCTTAATGTTGGGCTTTCTAGATCTTATTTAATCCAAAGTTTTGTGTGATTAGACAGTAAAAAAATGAATATAGAAATTTAAATACGTTCTTTACATGAACAATGACAATGAAGATTTTGATGAGTCATGGAGGTATACCACAAAAATATTTTAAGGATAAACATTGCTGAAAAGCTAAAATGCAAAGCACTAAAGAAATCAAAATTTAAATAATGTAAACAATAAATCCAGAAATTAAATATCAAAGACAGATTTGTGTTTATTTCCCTAAATTTTTCTTAATAAGGAAACACCTTCTCTTTTACTTTCCAATTATAGAAGGAAATGGAATAACTATGTAGTCTCCAAAACTGTTTTTATATGTAGCTATTAAGACCTAGTGCCTTTACAAATAACAACAAGGTAAAACAATCTAATTTGATCATATATAATATAATCATATTTTTCTATTCTGCTTCAGAGTGAAAAAAATATACTACAGCAGGGTGTTCAATCTTTTGGCTTCCCTGGGCCATGTTGGAAGAATTGTCTTGGGCCACACATAAAATACACTAACGCTAACAATAGCTGATAGGCTAAAAAAAAAAAATCTCATAATGTTTTAAGGAAGTTTACATATTTGTGATATTTGTGTTGGGCCACATTCAATGTCATCCTCGGCCACATGTGGCCCACAGGCCGCAGGTTGGACAAGCTTGTATCAGAGTCTTAAAAAGCATTTCACCAGTATGTTTTGAAAACAACTATTTTGATGAGCTTATAAACTTGGCAATTATATGATGCTGAAAAAGGGCTTTCTAATTGGTGATGTTAAGTCAGTATAACAAGGTAGTGAGAATTAACTTTGAACAAGCAGTTATTACTCTTAAATTGTCACATTTTAGAAACATTACAAGCTCCAAGAGCTGATAAAATACATGAGATAAGATAATGCAGATACTAAGATCTACCAGTTTCTATCTAAACATCCTGTGGAAAACTAATTCACTTTTTGGAGTTTTAATTTTCCTCATGTTTAAAACAGAAAAATAAAATAATTTCCTGAGTTCTTGTGAGTATGGGAAACAATGTTAATAAAGGGCCCTGATGACAGTGTAGCTTAAATGAGATCATTGCTGTTAATGGAGGTATTAAGGATGGTGCTGGTGCTAGTTCTGGAGAATCTTTCCCACAACGCCAATATGAAGGCTTTAATTCACACAAGCACCAGGAAGGTTGGCCCTTGTCACCTCATGGCCATCGATTACAGCCAGCCTCCTGACAAATATGAACCACTGCCAGAGGAGGAAACCAGATGTGTGGATGTCGACACGTCTTCCCATCTGTTAAGACTATTTGGTTATTCTTCGACTTTTATGTCCAGTTCTTAACGAATTGGCAAACAACTGACCAAACAACGAGGAAAATATAATTTTAGGATGAAGTATTTCAAAGGATGTTAAAGTATTGCTGGTTATAAAAAGTTTTATCTTCAAAACACTCATTTTCTGAAACTCCTTAAGAGAATAAAAATGACAATTTTCAGAAATATCAAACTTACAATATTTGAAGCTAAAAGAATTCTTCACAAAGGAATTGGGTATTTCATAGGAAAGCCATAAACAATTATAATACTCAAGAAAAACTCATCTTCACATTTCACTTTCCTTATGTACTAGTATAAACACAAAATTTTGTGTGATATTTCTTTGAAACTTTTAAACTCGTAATGTCTAAATATTTATCCTATATTTTGATAAGACTAAAATGATTTTCATGCATAGAAATTAAAAAAGGAGTTGAAAATAAGGAGTTTATTTAATATATGTCAATAGACAAAATAGTTCAATATTCTGTAAAAACTGGGTCCCACTTATTTTGAGCAGACTGCTGAAAGCTCATTTATTCTACATCAGTTGCATTTATACTTTTGTTCATCTCTTTTTCCATCCCATTTTAAATGTGAGCCCACCTATGTAAGAGTACTGGCACACATAGTAAGTACATTTTACAGAATTTGTGCAGTAACCAGCTACAGTTAACAATGCCAAAGCAGTCTATCCACCCACCATGAACTTAAGATTGAAGAAATGACAAATACAGGTCTTCTGCCAACAAACTGTGAAATTTAAGAAGCTTTTCTTTTTCTTGGCTGCATTTTTGGTCAACATGCAAAGGACTATTTCCTGCCATACAGGGAAGTCCTTAGGTGTTTATTAAATGTAAGTTTTGGCAAGATGAAGAATTATATGACAAACATACTTGTACTCTATTTTATTCTCTGACCCAGCACTGGAAACAATTTGCATCCTTCAAATTATATTCCAGAACTCACATAATTTAATTTCCATTAAATGCTTACATAATAGGCGAACCACGAAGTGAAAATATGGTCTTGCACATCATGGTGTAGGTGGATGTCACGGTGATTTTCTAATACAAGTTTATATTTCTAAATAAATTGAATTTTAGTTAAATCAGTCTAACATTTTTAATAGTCTCACCCACATAGATAGAGTGGGGATCTTATATGTAGTTGTTAAGAGTAGCAACTGATACTATACTCTAATGAAATATTTTGCCTAATAGAAATGCTTCTGAAAAGGTTCATGCAAATGATGCTTTTAATTAAAAAGTTGCATATAAATGTAATGACATTTTAAACATGATCAAAATGTTCTCTCTCTAAAGGAATACTGTAACAATTTTTTTGTTACGGAAAAACAATTATTCTCTAATTTATTTGTTTGAGAAACCTGGCTTTTAACTAATTGTATTTCCTTAAATGCAAGACTTGAAATTTTATTTTTTTATTTTTACTTTTTTAAATTTTGAGTTTATAAATTTAAAAAATTTTAATGTTAATTAAAATGGATCTTATTAAAAATTGTATTTCCTTTTGGGCTGAAACCATTTTTTAGGATGTCTATAAATCACCTTATACAGTTTTCATGATAGTTTAGTTACAACCAGCAAATCCTAAGCCACCAAAGTAATTCTAGGCTTCTAACAAGGATAAAAATAAATAAATAAGGAAGGCCACCACACTAATGGACATGAATTTAAAGAATAATGAAAATGAAAACCAAAAAAATAGGATTTCAGATTGTATTTTTTATTTAAGATATGACTCAAGATATTTTATTTTTTCAAGTGTTAGACTATCAGATTTTTAAAAATTCCCTAAGAAGAAAAAAAGAAAGAAAACTATTTAGTGAATCTGTACTGATTTTGTCCACTTCAATTCAGTCTTGTTTTTGGTGCTGTCCAAAGCTTGCTGAATAACTGCTAGGAATAAGAGCTGGACACGGCATACAGAGAGAATTAGAAATGCACTTTTATCAAAAAATCAGTCACTGTTATGTAAGGAGGATTGAGCTTAGACAATCTGTTGTGGTAATTTCTTTTTAAAAAAATACATAACCTACATTGCTTATTACAATATTTAGAAAGTTTTTATTTCATCATACAATTTAAATTCATCCTGTTTAATAAGCAAATTGATATATGATGCCAAGAAATATTTTGTTGTTTTACCATGACAAAGAAATTATAATGTTTAGATTTTGGACATTACTATTTGACTATTTTGTGAATTTGTTGTGCGAATAACAAGTATAATTTTACATTTTTTTTCAG
Seq C2 exon
AATTTTTATCAAAGTTCAGAGACTTCAGCAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139144-PIK3C2G:NM_004570:9
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0027315=Serum_albumin=PD(0.1=0.0)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)