HsaINT0125327 @ hg38
Intron Retention
Gene
ENSG00000186088 | GSAP
Description
gamma-secretase activating protein [Source:HGNC Symbol;Acc:HGNC:28042]
Coordinates
chr7:77311841-77312202:-
Coord C1 exon
chr7:77312101-77312202
Coord A exon
chr7:77311941-77312100
Coord C2 exon
chr7:77311841-77311940
Length
160 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGT
5' ss Score
10.67
3' ss Seq
AGAAGTGGTTTCCCTTTTAGCCT
3' ss Score
5.16
Exon sequences
Seq C1 exon
CTTATTGGGCAGAAGATTTGTAGACTTTGGGATCATCCTATGAGTTCTAACATCATTTCGCGGAACCACGTGACGCGACTGCTTCAGAACTATAAGAAACAG
Seq A exon
GTGAGTTTCTCTGAAAGCACAGCCAACTAAATGTTTTTAGGATCCTGTTTGCCCGTGACAACATATCTGTATGGACAGCAATTACAGTTCTTATCACTTTATTTTAAAATTGTGCTTATTGTGGAGAATCAGCTTACACCAGAAGTGGTTTCCCTTTTAG
Seq C2 exon
CCTCGGAATTCTATGATTAACAAGTCATCGTTCAGTGTAGAATTTCTGCCTCTGAACTACTTCATTGAAATTCTGACAGATATAGAGTCCTCCAATCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186088:ENST00000257626:29
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF056127=DUF781=FE(35.9=100)
A:
NA
C2:
PF056127=DUF781=PD(15.2=41.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTATTGGGCAGAAGATTTGTAGACT
R:
CTTGATTGGAGGACTCTATATCTGT
Band lengths:
202-362
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development